Publications by authors named "Fabien Garcon"

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Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
Brajesh P Kaistha, Gozde Kar, Andreas Dannhorn, Amanda Watkins, Grace Opoku-Ansah, Fabien Garcon

Cancer Biol Ther· December 2024

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A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells.
Kristoffer H Johansen, Dominic P Golec, Bonnie Huang, Chung Park, Julie H Thomsen

Sci Signal· July 2022

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Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model.
Doreen Lau, Fabien Garçon, Anita Chandra, Laura M Lechermann, Luigi Aloj

Front Immunol· April 2021

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Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment.
Susannah L Hewitt, Dyane Bailey, John Zielinski, Ameya Apte, Faith Musenge, Fabien Garcon

Clin Cancer Res· December 2020

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Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.
Robert A Benson, Fabien Garcon, Asha Recino, John R Ferdinand, Menna R Clatworthy

Front Immunol· July 2019

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PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.
Fabien Garçon, Klaus Okkenhaug

Immunol Cell Biol· May 2016

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Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage.
Ivan Angulo, Oscar Vadas, Fabien Garçon, Edward Banham-Hall, Vincent Plagnol

Science· November 2013

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Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma.
Dalya R Soond, Fabien Garçon, Daniel T Patton, Julia Rolf, Martin Turner

J Immunol· June 2012

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The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
Faruk Ramadani, Daniel J Bolland, Fabien Garcon, Juliet L Emery, Bart Vanhaesebroeck

Sci Signal· August 2010

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p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease.
Aurore Saudemont, Fabien Garçon, Hakim Yadi, Marta Roche-Molina, Nayoung Kim

Proc Natl Acad Sci U S A· April 2009

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CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.
Fabien Garçon, Daniel T Patton, Juliet L Emery, Emilio Hirsch, Robert Rottapel

Blood· February 2008

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Travel informations on the Tec kinases during lymphocyte activation.
Fabien Garçon, Jacques A Nunès

Adv Exp Med Biol· October 2006

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The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells.
Klaus Okkenhaug, Daniel T Patton, Antonio Bilancio, Fabien Garçon, Wendy C Rowan

J Immunol· October 2006

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The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.
Thijs J Hagenbeek, Marianne Naspetti, Fabrice Malergue, Fabien Garçon, Jacques A Nunès

J Exp Med· October 2004

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The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.
Fabien Garçon, Marguerite Ghiotto, Audrey Gérard, Wen-Chin Yang, Daniel Olive

Eur J Immunol· July 2004

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Tec kinase migrates to the T cell-APC interface independently of its pleckstrin homology domain.
Fabien Garçon, Georges Bismuth, Daniel Isnardon, Daniel Olive, Jacques A Nunès

J Immunol· July 2004

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Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase.
Audrey Gérard, Cédric Favre, Fabien Garçon, Jean-Guy Némorin, Pascale Duplay

Oncogene· February 2004

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