Publications by authors named "Fabio Spada"

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5-Ethynyluridine: A Bio-orthogonal Uridine Variant for mRNA-Based Therapies and Vaccines.
Sjors Maassen, Britt Coenen, Sara Dulk, Martijn van der Werff, Harry Warner, Fabio Spada

Chembiochem· March 2023

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Divergent Synthesis of Ultrabright and Dendritic Xanthenes for Enhanced Click-Chemistry-Based Bioimaging.
Luis Montiel, Fabio Spada, Antony Crisp, Sascha Serdjukow, Thomas Carell

Chemistry· January 2023

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AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins.
Tobias Becker, Cedric Cappel, Francesco Di Matteo, Giovanna Sonsalla, Ewelina Kaminska, Fabio Spada

iScience· December 2021

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Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.
Franziska R Traube, Dilara Özdemir, Hanife Sahin, Constanze Scheel, Andrea F Glück, Fabio Spada

Nat Commun· July 2021

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Active turnover of genomic methylcytosine in pluripotent cells.
Fabio Spada, Sarah Schiffers, Angie Kirchner, Yingqian Zhang, Gautier Arista

Nat Chem Biol· December 2020

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Isotope-dilution mass spectrometry for exact quantification of noncanonical DNA nucleosides.
Franziska R Traube, Sarah Schiffers, Katharina Iwan, Stefanie Kellner, Fabio Spada

Nat Protoc· January 2019

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Non-canonical Bases in the Genome: The Regulatory Information Layer in DNA.
Thomas Carell, Matthias Q Kurz, Markus Müller, Martin Rossa, Fabio Spada

Angew Chem Int Ed Engl· April 2018

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5-Formylcytosine to cytosine conversion by C-C bond cleavage in vivo.
Katharina Iwan, René Rahimoff, Angie Kirchner, Fabio Spada, Arne S Schröder

Nat Chem Biol· January 2018

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Quantitative LC-MS Provides No Evidence for m dA or m dC in the Genome of Mouse Embryonic Stem Cells and Tissues.
Sarah Schiffers, Charlotte Ebert, René Rahimoff, Olesea Kosmatchev, Jessica Steinbacher, Fabio Spada

Angew Chem Int Ed Engl· September 2017

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5-Formyl- and 5-Carboxydeoxycytidines Do Not Cause Accumulation of Harmful Repair Intermediates in Stem Cells.
René Rahimoff, Olesea Kosmatchev, Angie Kirchner, Toni Pfaffeneder, Fabio Spada

J Am Chem Soc· August 2017

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Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release.
Stefan Datz, Christian Argyo, Michael Gattner, Veronika Weiss, Korbinian Brunner, Fabio Spada

Nanoscale· April 2016

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DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination.
Weihua Qin, Patricia Wolf, Nan Liu, Stephanie Link, Martha Smets, Fabio Spada

Cell Res· August 2015

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Cell-penetrating and neurotargeting dendritic siRNA nanostructures.
Korbinian Brunner, Johannes Harder, Tobias Halbach, Julian Willibald, Fabio Spada

Angew Chem Int Ed Engl· February 2015

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Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Toni Pfaffeneder, Fabio Spada, Mirko Wagner, Caterina Brandmayr, Silvia K Laube

Nat Chem Biol· July 2014

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Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions.
Mike De Vos, Rosy El Ramy, Delphine Quénet, Patricia Wolf, Fabio Spada

J Biol Chem· June 2014

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Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules.
Nan Liu, Mengxi Wang, Wen Deng, Christine S Schmidt, Weihua Qin, Fabio Spada

PLoS One· December 2013

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Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state.
Christine S Schmidt, Sebastian Bultmann, Daniela Meilinger, Benedikt Zacher, Achim Tresch, Fabio Spada

PLoS One· June 2013

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Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers.
Sebastian Bultmann, Robert Morbitzer, Christine S Schmidt, Katharina Thanisch, Fabio Spada

Nucleic Acids Res· July 2012

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Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5-hydroxymethylcytosine.
Aleksandra Szwagierczak, Andreas Brachmann, Christine S Schmidt, Sebastian Bultmann, Heinrich Leonhardt, Fabio Spada

Nucleic Acids Res· July 2011

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Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1.
Weihua Qin, Heinrich Leonhardt, Fabio Spada

J Cell Biochem· February 2011

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Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.
Carina Frauer, Andrea Rottach, Daniela Meilinger, Sebastian Bultmann, Karin Fellinger, Fabio Spada

PLoS One· February 2011

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Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA.
Aleksandra Szwagierczak, Sebastian Bultmann, Christine S Schmidt, Fabio Spada, Heinrich Leonhardt

Nucleic Acids Res· October 2010

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The multi-domain protein Np95 connects DNA methylation and histone modification.
Andrea Rottach, Carina Frauer, Garwin Pichler, Ian Marc Bonapace, Fabio Spada

Nucleic Acids Res· April 2010

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Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.
Daniela Meilinger, Karin Fellinger, Sebastian Bultmann, Ulrich Rothbauer, Ian Marc Bonapace, Fabio Spada

EMBO Rep· November 2009

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DNA methylation-mediated epigenetic control.
Andrea Rottach, Heinrich Leonhardt, Fabio Spada

J Cell Biochem· September 2009

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