Publications by authors named "Fabiola Moretti"

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Targeting the MDM2-MDM4 interaction interface reveals an otherwise therapeutically active wild-type p53 in colorectal cancer.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Fabiola Moretti

Mol Oncol· August 2025

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Estrogen rescues muscle regeneration impaired by DUX4 in a humanized xenograft mouse model.
Silvia Maiullari, Giada Mele, Patrizia Calandra, Giorgia di Blasio, Sonia Valentini, Fabiola Moretti

Cell Death Dis· July 2025

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Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment.
Francesca Sardina, Federica Polverino, Sonia Valentini, Claudia Carsetti, Elisabetta Falvo, Fabiola Moretti

Cell Death Discov· February 2025

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Rational design, synthesis, and biophysical characterization of a peptidic MDM2-MDM4 interaction inhibitor.
Marco Ballarotto, Elisa Bianconi, Sonia Valentini, Andrea Temperini, Fabiola Moretti

Bioorg Med Chem· November 2024

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HIPK2 Cooperates with KRAS Signaling and Associates with Colorectal Cancer Progression.
Micol Di Segni, Ilaria Virdia, Alessandra Verdina, Carla Azzurra Amoreo, Silvia Baldari, Fabiola Moretti

Mol Cancer Res· May 2022

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Early Social Enrichment Modulates Tumor Progression and p53 Expression in Adult Mice.
Silvia Middei, Ludovica Giorgini, Valentina Vacca, Francesca Storri, Sabrina Putti, Fabiola Moretti

Biomolecules· March 2022

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p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity.
Andrea Arena, Antonio Stigliano, Eugenia Belcastro, Ezio Giorda, Maria Manuela Rosado, Fabiola Moretti

Front Immunol· December 2021

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Role of Sex in the Therapeutic Targeting of p53 Circuitry.
Francesca Mancini, Ludovica Giorgini, Emanuela Teveroni, Alfredo Pontecorvi, Fabiola Moretti

Front Oncol· July 2021

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Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties.
Rossella Lucà, Maria Rita Assenza, Fabio Maiullari, Luisa Pieroni, Silvia Maiullari, Fabiola Moretti

Cell Death Dis· May 2021

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organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles.
Fabio Maiullari, Maila Chirivì, Marco Costantini, Anna Maria Ferretti, Sandro Recchia, Fabiola Moretti

Biofabrication· April 2021

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Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells.
Cinzia Caggiano, Eugenia Guida, Federica Todaro, Pamela Bielli, Mattia Mori, Fabiola Moretti

Cell Death Discov· October 2020

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Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients.
Marsha Pellegrino, Gianandrea Traversi, Andrea Arena, Marco Cappa, M Manuela Rosado, Fabiola Moretti

PLoS One· April 2020

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Concentration of Metals and Trace Elements in the Normal Human and Rat Thyroid: Comparison with Muscle and Adipose Tissue and Volcanic Versus Control Areas.
Pasqualino Malandrino, Marco Russo, Anna Ronchi, Fabiola Moretti, Fiorenza Gianì

Thyroid· February 2020

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Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4.
Rossella Lucà, Giorgia di Blasio, Daniela Gallo, Valentina Monteleone, Isabella Manni, Fabiola Moretti

Cancers (Basel)· September 2019

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Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation.
Emilia Luca, Laura Fici, Anna Ronchi, Ferdinando Marandino, Esther Diana Rossi, Fabiola Moretti

J Exp Clin Cancer Res· June 2017

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Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity.
Emanuela Teveroni, Marsha Pellegrino, Sabrina Sacconi, Patrizia Calandra, Isabella Cascino, Fabiola Moretti

J Clin Invest· April 2017

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MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability.
Francesca Mancini, Emanuela Teveroni, Giusy Di Conza, Valentina Monteleone, Ivan Arisi, Fabiola Moretti

Mol Cancer· March 2017

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MDM2-MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance.
Ilaria Moscetti, Emanuela Teveroni, Fabiola Moretti, Anna Rita Bizzarri, Salvatore Cannistraro

Int J Nanomedicine· February 2017

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The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.
Giusy Di Conza, Sarah Trusso Cafarello, Stefan Loroch, Daniela Mennerich, Sofie Deschoemaeker, Fabiola Moretti

Cell Rep· February 2017

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Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.
Nadia Canu, Ilaria Pagano, Luca Rosario La Rosa, Marsha Pellegrino, Maria Teresa Ciotti, Fabiola Moretti

Front Mol Neurosci· January 2017

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Peptides and peptidomimetics in the p53/MDM2/MDM4 circuitry - a patent review.
Emanuela Teveroni, Rossella Lucà, Marsha Pellegrino, Germana Ciolli, Alfredo Pontecorvi, Fabiola Moretti

Expert Opin Ther Pat· December 2016

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Allele-specific DNA hypomethylation characterises FSHD1 and FSHD2.
Patrizia Calandra, Isabella Cascino, Richard J L F Lemmers, Giuliana Galluzzi, Emanuela Teveroni, Fabiola Moretti

J Med Genet· May 2016

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Novel insights about the MDM2/MDM4 heterodimer.
Fabiola Moretti

Mol Cell Oncol· March 2016

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Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.
Marsha Pellegrino, Francesca Mancini, Rossella Lucà, Alice Coletti, Nicola Giacchè, Fabiola Moretti

Cancer Res· November 2015

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The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells.
Alessia Garufi, Valentina Ubertini, Francesca Mancini, Valerio D'Orazi, Silvia Baldari, Fabiola Moretti

J Exp Clin Cancer Res· August 2015

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