Publications by authors named "Fadumo A Isse"

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The clinical implication of inflammation-driven regulation of drug-metabolizing enzymes.
Sara R El-Mahrouk, Samar H Gerges, Sara A Helal, Fadumo A Isse, Ahmad H Alammari

Expert Opin Drug Metab Toxicol· November 2025

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Unraveling enantioselective metabolism: Human cytochrome P450s in arachidonic acid biotransformation.
Fadumo Ahmed Isse, Ahmed A El-Sherbeni, Ayman O S El-Kadi

Drug Metab Dispos· November 2025

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Effect of Cannabistilbene I in Attenuating Angiotensin II-Induced Cardiac Hypertrophy: Insights into Cytochrome P450s and Arachidonic Acid Metabolites Modulation.
Ahmad H Alammari, Fadumo Ahmed Isse, Conor O'Croinin, Neal M Davies, Ayman O S El-Kadi

Cannabis Cannabinoid Res· April 2025

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Alteration of Hepatic Cytochrome P450 Expression and Arachidonic Acid Metabolism by Arsenic Trioxide (ATO) in C57BL/6 Mice.
Mahmoud A El-Ghiaty, Mohammed A Alqahtani, Sara R El-Mahrouk, Fadumo A Isse, Ahmad H Alammari

Biol Trace Elem Res· February 2025

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Quantification of Epoxyeicosatrienoic acids Enantiomers: The development of reliable and practical liquid chromatography mass Spectrometry assay.
Fadumo A Isse, Sara Helal, Ahmed A El-Sherbeni, Dion R Brocks, Ayman O S El-Kadi

J Chromatogr B Analyt Technol Biomed Life Sci· October 2024

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Cytochrome P450 1B1 is critical in the development of TNF-α, IL-6, and LPS-induced cellular hypertrophy.
Mohammed A W ElKhatib, Samar H Gerges, Fadumo A Isse, Ayman O S El-Kadi

Can J Physiol Pharmacol· July 2024

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Modulation of Angiotensin II-Induced Cellular Hypertrophy by Cannflavin-C: Unveiling the Impact on Cytochrome P450 1B1 and Arachidonic Acid Metabolites.
Ahmad H Alammari, Fadumo Ahmed Isse, Conor O'Croinin, Neal M Davies, Ayman O S El-Kadi

Drug Metab Dispos· July 2024

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16R-HETE and 16S-HETE alter human cytochrome P450 1B1 enzyme activity probably through an allosteric mechanism.
Rahmat Hidayat, Sherif M Shoieb, Farag E S Mosa, Khaled Barakat, Dion R Brocks, Fadumo A Isse

Mol Cell Biochem· June 2024

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Nimodipine systemic exposure and outcomes following aneurysmal subarachnoid hemorrhage: a pilot prospective observational study (ASH-1 study).
Sherif Hanafy Mahmoud, Fatma Hefny, Fadumo Ahmed Isse, Shahmeer Farooq, Spencer Ling

Front Neurol· January 2024

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17-(R/S)-hydroxyeicosatetraenoic acid (HETE) induces cardiac hypertrophy through the CYP1B1 in enantioselective manners.
Fadumo Ahmed Isse, Ahmad H Alammari, Ahmed A El-Sherbeni, Ayman O S El-Kadi

Prostaglandins Other Lipid Mediat· October 2023

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Sex- and enantiospecific differences in the formation rate of hydroxyeicosatetraenoic acids in rat organs.
Samar H Gerges, Ahmad H Alammari, Mahmoud A El-Ghiaty, Fadumo A Isse, Ayman O S El-Kadi

Can J Physiol Pharmacol· August 2023

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Physiological and pathophysiological roles of hepoxilins and their analogs.
Sara A Helal, Fadumo Ahmed Isse, Samar H Gerges, Ayman O S El-Kadi

Drug Metab Rev· August 2023

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6-Formylindolo[3,2-b]carbazole Protects Against Angiotensin II-Induced Cellular Hypertrophy through the Induction of Cytochrome P450 1A1 and Its Associated 19(S)-HETE Metabolite In Vitro.
Ahmad H Alammari, Samar H Gerges, Fadumo Ahmed Isse, Ayman O S El-Kadi

Drug Metab Dispos· July 2023

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The enantioselective separation and quantitation of the hydroxy-metabolites of arachidonic acid by liquid chromatography - tandem mass spectrometry.
Fadumo Ahmed Isse, Ahmad H Alammari, Ahmed A El-Sherbeni, Dion R Brocks, Ayman O S El-Kadi

Prostaglandins Other Lipid Mediat· April 2023

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Effect of inflammation on cytochrome P450-mediated arachidonic acid metabolism and the consequences on cardiac hypertrophy.
Mohammed A W ElKhatib, Fadumo Ahmed Isse, Ayman O S El-Kadi

Drug Metab Rev· April 2023

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The multifaceted role of cytochrome P450-Derived arachidonic acid metabolites in diabetes and diabetic cardiomyopathy.
Fadumo Ahmed Isse, Ahmed A El-Sherbeni, Ayman O S El-Kadi

Drug Metab Rev· May 2022

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Identifying simultaneous matrix metalloproteinases/soluble epoxide hydrolase inhibitors.
Ahmed A El-Sherbeni, Rabia Bhatti, Fadumo A Isse, Ayman O S El-Kadi

Mol Cell Biochem· March 2022

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The Impact of Nimodipine Administration through Feeding Tube on Outcomes in Patients with Aneurysmal Subarachnoid Hemorrhage.
Fadumo Ahmed Isse, Yasmeen El Hajj Abdallah, Sherif Hanafy Mahmoud

J Pharm Pharm Sci· April 2021

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Enantioselective assay of nimodipine in human plasma using liquid chromatography-tandem mass spectrometry.
Fadumo Ahmed Isse, Tyson Le, Sherif Hanafy Mahmoud

Biomed Chromatogr· February 2021

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Nimodipine Pharmacokinetic Variability in Various Patient Populations.
Sherif Hanafy Mahmoud, Xinqi Ji, Fadumo Ahmed Isse

Drugs R D· December 2020

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