Publications by authors named "Fangle Liu"

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A mouse model of sepsis-associated DIC induced by Kappa-carrageenan and Lipopolysaccharides: Establishment and characteristics.
Ping Tang, Boning Huang, Qianqing Ou, Fangle Liu, Liuqing Lin

J Adv Res· January 2026

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LianZhiXiaoYan formula alleviates LPS-induced chronic pneumonia via regulating metabolic reprogramming through SIRT3-SDH-SUCNR1 signaling pathway.
Siyuan Liu, Jincheng Lv, Peng Peng, Xianshu Song, Pengyu Dai, Fangle Liu

J Ethnopharmacol· January 2026

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Xiebai San mediates the NCOA2-ESR1/2 signaling pathway to intervene in interstitial pneumonia.
Yufeng Yao, Lijun Shao, Ziqi Li, Jiahao Liang, Chenchen Zhu, Fangle Liu

Phytomedicine· December 2025

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Zhilining formula suppresses ferroptosis in colonic epithelial cells by inhibiting ALOX15/15(S)-HPETE to repress colorectal tumorigenesis and progression.
Rui Zhou, Pengyu Dai, Jiaxin Li, Chengxi Guo, Meiqi Wang, Fangle Liu

Phytomedicine· December 2025

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Brunodelphinine A alleviates non-alcoholic fatty liver disease by inhibiting oxidative stress and regulating lipid metabolism via NOX4/SIRT1/PPARs axis.
Meiqi Wang, Beixuan Yang, Xin Li, Huanhuan Ma, Xia Ou, Fangle Liu

Phytomedicine· November 2025

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Two new alkaloids identified from herb French, a famous Tibetan drug "Gebu Dilu".
Siyuan Liu, Yuansheng Zou, Zeren Dawa, Fangle Liu, Meiqi Wang

Nat Prod Res· October 2025

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Brunodelphinone and Brunodelphinine a, two novel C-diterpenoid alkaloids isolated from Delphinium brunonianum Royle.
Yuan-Sheng Zou, Ze-Ren Dawa, Fang-le Liu, Mei-Qi Wang, Chen-Chen Zhu

Fitoterapia· June 2025

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Reaction-Based Fluorescence Assays for the Determination of Food Trimethylamine Oxide.
Danfeng Peng, Xinxin Huang, Qiling Wang, Liying Huang, Fang Liu, Fangle Liu

Luminescence· December 2024

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Xuefu Zhuyu decoction alleviates deep vein thrombosis through inhibiting the activation of platelets and neutrophils via sirtuin 1/nuclear factor kappa-B pathway.
Boning Huang, Ping Tang, Youchen Liu, Fangle Liu, Yuying Zheng, Liuqing Lin

J Ethnopharmacol· October 2024

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Trichodelphinine A alleviates pulmonary fibrosis by inhibiting collagen synthesis via NOX4-ARG1/TGF-β signaling pathway.
Fangle Liu, Yufeng Yao, Chengxi Guo, Pengyu Dai, Jinhao Huang

Phytomedicine· September 2024

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Zhilining Formula alleviates DSS-induced colitis through suppressing inflammation and gut barrier dysfunction via the AHR/NF-κBp65 axis.
Rui Zhou, Kaiwen Huang, Simin Chen, Meiqi Wang, Fang Liu, Fangle Liu

Phytomedicine· July 2024

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Betulinic acid induces apoptosis of HeLa cells via ROS-dependent ER stress and autophagy in vitro and in vivo.
Ping Chen, Xueer Zhang, Qiaomiao Fang, Zhongxiang Zhao, Chaozhan Lin, Fangle Liu

J Nat Med· June 2024

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Integrating plasma metabolomics and gut microbiome to reveal the mechanisms of Huangqi Guizhi Wuwu Decoction intervene diabetic peripheral neuropathy.
Kaihui Zhang, Peng Peng, Jinhao Huang, Ming Chen, Fangle Liu

J Ethnopharmacol· January 2024

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Wedelolactone alleviates cholestatic liver injury by regulating FXR-bile acid-NF-κB/NRF2 axis to reduce bile acid accumulation and its subsequent inflammation and oxidative stress.
Mei-Qi Wang, Kai-Hui Zhang, Fang-Le Liu, Rui Zhou, Yun Zeng

Phytomedicine· January 2024

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Pen Yan Jing Tablets Alleviates Pelvic Inflammatory Disease by Inhibiting Akt/NF-κB Pathway.
Ping Tang, Qi Ding, Juan Lin, Xinrong Yang, Yiting Wang, Fangle Liu, Liuqing Lin

Int J Med Sci· November 2023

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β-Carboline alkaloids from Picrasma quassioides and their 3D-QSAR study on anti-inflammation in LPS-induced RAW 264.7 cells.
Pengyu Dai, Simin Chen, Meiqi Wang, Huanhuan Ma, Fangle Liu

Fitoterapia· April 2023

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Corrigendum to "Network pharmacology-based mechanism prediction and pharmacological validation of Xiaoyan Lidan formula on attenuating alpha-naphthylisothiocyanate induced cholestatic hepatic injury in rats" [J. Ethnopharmacol. 270 (2021) 113816].
Meiqi Wang, Fangle Liu, Yufeng Yao, Qiuyu Zhang, Zenghui Lu, Changhui Liu

J Ethnopharmacol· March 2023

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Nigakinone alleviates DSS-induced experimental colitis via regulating bile acid profile and FXR/NLRP3 signaling pathways.
Fangle Liu, Yufeng Yao, Qian Wang, Fengxue Zhang, Meiqi Wang

Phytother Res· January 2023

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A comparative study of Liandan Xiaoyan Formula metabolic profiles in control and colitis rats by UPLC-Q-TOF-MS combined with chemometrics.
Qian Wang, Meiqi Wang, Ningyu Li, Simin Chen, Huanhuan Ma, Fangle Liu

J Pharm Biomed Anal· January 2023

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Integrating metabolomics and network pharmacology to reveal the mechanisms of Delphinium brunonianum extract against nonalcoholic steatohepatitis.
Kaihui Zhang, Yue Yuan, Zeren Dawa, Fangle Liu, Yufeng Yao

J Ethnopharmacol· July 2022

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Pharmacokinetic Study of Four Major Bioactive Components of Liandan Xiaoyan Formula in Ulcerative Colitis and Control Rats Using UPLC-MS/MS.
Kaihui Zhang, Zenghui Lu, Qian Wang, Fangle Liu, Meiqi Wang

Front Pharmacol· July 2022

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Comparative Pharmacokinetics of Three Bioactive Diterpenoids of Extract in Normal and Con A-Induced Liver Injury Rats Using UPLC-MS/MS.
Fangle Liu, Yun Zeng, Pengyu Dai, Kaiwen Huang, Kaihui Zhang

Front Pharmacol· July 2022

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Authentication and Quality Assessment of Plumeriae Rubrae Flos by UHPLC-QTOF-MS/MS and UHPLC-DAD Combined With Chemometrics.
Yufeng Yao, Yuanyuan Xie, Pengyu Dai, Yunxia Ma, Chenchen Zhu, Fangle Liu

J AOAC Int· June 2022

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Diterpenoid alkaloids isolated from Delphinium trichophorum alleviate pulmonary fibrosis via the TGF-β/Smad pathway in 3T6 and HFL-1 cells.
Yufeng Yao, Yuanyuan Chen, Dawa Zeren, Yunxia Ma, Yuanyuan Xie, Fangle Liu

Biomed Pharmacother· May 2022

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Diterpenoid Alkaloids Isolated from and Their Inhibitory Effects on Hepatocytes Lipid Accumulation.
Huanhuan Ma, Yunxia Ma, Zeren Dawa, Yufeng Yao, Meiqi Wang, Fangle Liu

Molecules· March 2022

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