Publications by authors named "Fatema Al-Rashed"

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Gut microbiota: a promising new target in immune tolerance.
Nourah Almansour, Fatema Al-Rashed, Khubaib Choudhry, Hend Alqaderi, Sardar Sindhu

Front Immunol· October 2025

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Verapamil Restores β-Cell Mass and Function in Diabetogenic Stress Models via Proliferation and Mitochondrial Respiration.
Hossein Arefanian, Fatema Al-Rashed, Fawaz Alzaid, Fatemah Bahman, Nermeen Abukhalaf

Cells· October 2025

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Immune cell-adipose tissue crosstalk in metabolic diseases with a focus on type 1 diabetes.
Fawaz Alzaid, Guy Fagherazzi, Jean-Pierre Riveline, Fatemah Bahman, Fatema Al-Rashed

Diabetologia· August 2025

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Sex-Specific Differences in Adipose IRF5 Expression and Its Association with Inflammation and Insulin Resistance in Obesity.
Shihab Kochumon, Noelle Benobaid, Ashraf Al Madhoun, Shaima Albeloushi, Nourah Almansour, Fatema Al-Rashed

Int J Mol Sci· August 2025

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Eicosapentaenoic Acid (EPA) Alleviates LPS-Induced Oxidative Stress via the PPARα-NF-κB Axis.
Haya AlAbduljader, Halemah AlSaeed, Amenah Alrabeea, Ameenah Sulaiman, Mohammed J A Haider, Fatema Al-Rashed

Oxid Med Cell Longev· June 2025

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Impact of sleep deprivation on monocyte subclasses and function.
Fatema Al-Rashed, Halemah Alsaeed, Nadeem Akhter, Haya Alabduljader, Fahd Al-Mulla

J Immunol· March 2025

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Comparative efficacy, toxicity, and insulin-suppressive effects of simvastatin and pravastatin in fatty acid-challenged mouse insulinoma MIN6 β-cell model.
Hossein Arefanian, Sardar Sindhu, Fatema Al-Rashed, Fawaz Alzaid, Ashraf Al Madhoun

Front Endocrinol (Lausanne)· November 2024

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IL-6R (trans-signaling) is a key regulator of reverse cholesterol transport in lipid-laden macrophages.
Fatema Al-Rashed, Halemah AlSaeed, Nourah Almansour, Fahd Al-Mulla, Yusuf A Hannun

Clin Immunol· October 2024

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Soybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice.
Texy Jacob, Sardar Sindhu, Amal Hasan, Md Zubbair Malik, Hossein Arefanian, Fatema Al-Rashed

Front Microbiol· August 2024

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Aryl hydrocarbon receptor: current perspectives on key signaling partners and immunoregulatory role in inflammatory diseases.
Fatemah Bahman, Khubaib Choudhry, Fatema Al-Rashed, Fahd Al-Mulla, Sardar Sindhu

Front Immunol· August 2024

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PPARdelta: A key modulator in the pathogenesis of diabetes mellitus and co-morbidity.
Halemah AlSaeed, Mohammed J A Haider, Fawaz Alzaid, Fahd Al-Mulla, Rasheed Ahmad, Fatema Al-Rashed

iScience· July 2024

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TNF-α/Stearate Induced H3K9/18 Histone Acetylation Amplifies IL-6 Expression in 3T3-L1 Mouse Adipocytes.
Fatemah Bahman, Areej Al-Roub, Nadeem Akhter, Ashraf Al Madhoun, Ajit Wilson, Fatema Al-Rashed

Int J Mol Sci· June 2024

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Gut Dysbiosis Shaped by Cocoa Butter-Based Sucrose-Free HFD Leads to Steatohepatitis, and Insulin Resistance in Mice.
Shihab Kochumon, Md Zubbair Malik, Sardar Sindhu, Hossein Arefanian, Texy Jacob, Fatema Al-Rashed

Nutrients· June 2024

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Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models.
Hossein Arefanian, Ashraf Al Madhoun, Fatema Al-Rashed, Fawaz Alzaid, Fatemah Bahman

Cells· May 2024

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Investigating the Role of FABP4 in Diabetes and Obesity and the Influence of Age and Ethnicity: A Comprehensive Analysis of a Cohort from the KEDP-Study.
Mohammed A Abdalla, Jehad Abubaker, Mohamed Abu-Farha, Irina Al-Khairi, Preethi Cherian, Fatema Al-Rashed

Int J Mol Sci· April 2024

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Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation.
Fatema Al-Rashed, Hossein Arefanian, Ashraf Al Madhoun, Fatemah Bahman, Sardar Sindhu

Cells· March 2024

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Differential effects of fish-oil and cocoa-butter based high-fat/high-sucrose diets on endocrine pancreas morphology and function in mice.
Shaima Albeloushi, Amal Hasan, Hossein Arefanian, Sardar Sindhu, Fatema Al-Rashed

Front Endocrinol (Lausanne)· February 2024

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Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways.
Nadeem Akhter, Ajit Wilson, Hossein Arefanian, Reeby Thomas, Shihab Kochumon, Fatema Al-Rashed

Int J Mol Sci· October 2023

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TNFα induces matrix metalloproteinase-9 expression in monocytic cells through ACSL1/JNK/ERK/NF-kB signaling pathways.
Areej Al-Roub, Nadeem Akhter, Fatema Al-Rashed, Ajit Wilson, Fawaz Alzaid

Sci Rep· September 2023

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The role of TLR2 in exercise-induced immunomodulation in normal weight individuals.
Fatemah Bahman, Halemah AlSaeed, Shaima Albeloushi, Fahd Al-Mulla, Rasheed Ahmad, Fatema Al-Rashed

Sci Rep· July 2023

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ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding.
Fatema Al-Rashed, Dania Haddad, Ashraf Al Madhoun, Sardar Sindhu, Texy Jacob

iScience· July 2023

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Metabolomics: a promising tool for deciphering metabolic impairment in heavy metal toxicities.
Muhammad Sajid Hamid Akash, Azka Yaqoob, Kanwal Rehman, Muhammad Imran, Mohammed A Assiri, Fatema Al-Rashed

Front Mol Biosci· July 2023

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Macrophages and the development and progression of non-alcoholic fatty liver disease.
Bader Alabdulaali, Fatema Al-Rashed, Mohammed Al-Onaizi, Anwar Kandari, Joanna Razafiarison

Front Immunol· June 2023

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Cysteine dioxygenase type 1: A new player in adipose physiology and metabolic health.
Sardar Sindhu, Fatema Al-Rashed, Rasheed Ahmad

EBioMedicine· December 2022

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Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity.
Shihab Kochumon, Hossein Arefanian, Sardar Sindhu, Reeby Thomas, Texy Jacob, Fatema Al-Rashed

Cells· December 2022

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