Publications by authors named "Fatima Bosch"

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Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.
Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A Blasco

August 2012

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Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism.
Jérémy Dufau, Emeline Recazens, Laura Bottin, Camille Bergoglio, Aline Mairal, Fatima Bosch

Cell Metab· November 2025

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Rat models of musculoskeletal lysosomal storage disorders and their role in pre-clinical evaluation of gene therapy approaches.
Sara Marcó, Sergio Muñoz, Fatima Bosch, Veronica Jimenez

Mamm Genome· June 2025

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Reversion of metabolic dysfunction-associated steatohepatitis by skeletal muscle-directed FGF21 gene therapy.
Veronica Jimenez, Victor Sacristan, Claudia Jambrina, Maria Luisa Jaen, Estefania Casana, Fatima Bosch

Mol Ther· December 2024

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Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy.
Sergio Muñoz, Joan Bertolin, Veronica Jimenez, Maria Luisa Jaén, Miquel Garcia, Fatima Bosch

Mol Metab· March 2024

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Arginine reprograms metabolism in liver cancer via RBM39.
Dirk Mossmann, Christoph Müller, Sujin Park, Brendan Ryback, Marco Colombi, Fatima Bosch

Cell· November 2023

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Integrated gene expression profiles reveal a transcriptomic network underlying the thermogenic response in adipose tissue.
Jordi Rodó, Miquel Garcia, Estefania Casana, Sergio Muñoz, Claudia Jambrina, Fatima Bosch

Sci Rep· May 2023

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Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse.
Inka Rapöhn, Ivet Elias, Juliane Weiner, Anna Pujol, Stephanie Kehr, Fatima Bosch

Front Endocrinol (Lausanne)· May 2023

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CDK4 is an essential insulin effector in adipocytes.
Sylviane Lagarrigue, Isabel C Lopez-Mejia, Pierre-Damien Denechaud, Xavier Escoté, Judit Castillo-Armengol, Fatima Bosch

J Clin Invest· March 2023

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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Justine M Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Fatima Bosch

BMC Biol· February 2023

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Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes.
Kendall Higgins, Bret A Moore, Zorana Berberovic, Hibret A Adissu, Mohammad Eskandarian, Fatima Bosch

Sci Rep· December 2022

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Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
Francois Moreau, Nicholas S Kirk, Fa Zhang, Vasily Gelfanov, Edward O List, Fatima Bosch

Nat Commun· November 2022

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CDK4 is an essential insulin effector in adipocytes.
Sylviane Lagarrigue, Isabel C Lopez-Mejia, Pierre-Damien Denechaud, Xavier Escoté, Judit Castillo-Armengol, Fatima Bosch

J Clin Invest· July 2022

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AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity.
Estefania Casana, Veronica Jimenez, Claudia Jambrina, Victor Sacristan, Sergio Muñoz, Fatima Bosch

Mol Ther Methods Clin Dev· June 2022

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Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa.
Alonso Sánchez-Cruz, Alberto Hernández-Pinto, Concepción Lillo, Carolina Isiegas, Miguel Marchena, Fátima Bosch

Cell Death Dis· April 2022

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Seven-year follow-up of durability and safety of AAV CNS gene therapy for a lysosomal storage disorder in a large animal.
Sara Marcó, Virginia Haurigot, Maria Luisa Jaén, Albert Ribera, Víctor Sánchez, Fatima Bosch

Mol Ther Methods Clin Dev· December 2021

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Treatment of skeletal and non-skeletal alterations of Mucopolysaccharidosis type IVA by AAV-mediated gene therapy.
Joan Bertolin, Víctor Sánchez, Albert Ribera, Maria Luisa Jaén, Miquel Garcia, Fatima Bosch

Nat Commun· September 2021

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Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.
Roxana Khatib Shahidi, Jenny M Hoffmann, Shahram Hedjazifar, Laurianne Bonnet, Ritesh K Baboota, Fatima Bosch

PLoS One· August 2021

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Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function.
Miriam Ejarque, Joan Sabadell-Basallote, Daniel Beiroa, Enrique Calvo, Noelia Keiran, Fatima Bosch

Br J Pharmacol· May 2021

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BMP7 overexpression in adipose tissue induces white adipogenesis and improves insulin sensitivity in ob/ob mice.
Estefania Casana, Veronica Jimenez, Victor Sacristan, Sergio Muñoz, Claudia Jambrina, Fatima Bosch

Int J Obes (Lond)· February 2021

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Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging.
Sergio Piñeiro-Hermida, Chiara Autilio, Paula Martínez, Fátima Bosch, Jesús Pérez-Gil

J Cell Biol· October 2020

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Vitamin D Receptor Overexpression in β-Cells Ameliorates Diabetes in Mice.
Meritxell Morró, Laia Vilà, Sylvie Franckhauser, Cristina Mallol, Gemma Elias, Fàtima Bosch

Diabetes· May 2020

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The Deep Genome Project.
K C Kent Lloyd, David J Adams, Gareth Baynam, Arthur L Beaudet, Fatima Bosch

Genome Biol· February 2020

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BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice.
Jenny M Hoffmann, John R Grünberg, Ann Hammarstedt, Tobias Kroon, Thomas U Greiner, Fatima Bosch

Mol Metab· February 2020

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Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
Marita Westhrin, Toril Holien, Muhammad Zahoor, Siv Helen Moen, Glenn Buene, Fatima Bosch

JBMR Plus· January 2020

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Breaking the Barriers of Genetic and Metabolic Disorders.
Hildegard Büning, Fatima Bosch, Federico Mingozzi

Hum Gene Ther· October 2019

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