Publications by authors named "Federico Corelli"

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Reducing effects of isoliquiritigenin, a naturally occurring GABA receptor agonist, on alcohol-motivated behaviors in alcohol-preferring rats.
Paola Maccioni, Laura Regonini Somenzi, Mauro A M Carai, Federico Corelli, Gian Luigi Gessa

Psychopharmacology (Berl)· September 2025

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Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor.
Federica Poggialini, Paolo Governa, Chiara Vagaggini, Samuele Maramai, Stefania Lamponi, Federico Corelli

Eur J Pharm Sci· June 2025

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Indole-2-Carboxamide as an Effective Scaffold for the Design of New TRPV1 Agonists.
Samuele Maramai, Claudia Mugnaini, Marco Paolino, Aniello Schiano Moriello, Luciano De Petrocellis, Federico Corelli

Molecules· February 2025

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Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.
Claudia Mugnaini, Antonella Brizzi, Marco Paolino, Enrico Scarselli, Riccardo Castelli, Federico Corelli

ACS Chem Neurosci· March 2024

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Reducing effect of intragastrically administered saikosaponin A on alcohol and sucrose self-administration in rats.
Paola Maccioni, Young-Won Chin, Federico Corelli, Hak Cheol Kwon, Giancarlo Colombo

Nat Prod Res· December 2023

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Anorectic effect of COR659 in a rat model of overeating.
Paola Maccioni, Claudia Mugnaini, Mauro A M Carai, Gian Luigi Gessa, Federico Corelli

Behav Pharmacol· October 2023

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Investigation on Novel 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity.
Marco Paolino, Modesto de Candia, Rosa Purgatorio, Marco Catto, Mario Saletti, Federico Corelli

Molecules· August 2023

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Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Claudia Mugnaini, Magdalena Kostrzewa, Marta Casini, Poulami Kumar, Valeria Catallo, Federico Corelli

Molecules· June 2023

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-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists.
Isabella Romeo, Antonella Brizzi, Federica Pessina, Francesca Alessandra Ambrosio, Francesca Aiello, Federico Corelli

J Med Chem· May 2023

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The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition.
Vittoria Borgonetti, Claudia Mugnaini, Federico Corelli, Nicoletta Galeotti

Biomedicines· May 2023

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Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant .
Filomena Sannio, Antonella Brizzi, Rosita Del Prete, Marialuce Avigliano, Tiziana Simone, Federico Corelli

Antibiotics (Basel)· December 2022

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Development of tolerance upon repeated administration with the GABA receptor positive allosteric modulator, COR659, on alcohol drinking in rodents.
Irene Lorrai, Chase Shankula, Jorge Marquez Gaytan, Riccardo Maccioni, Carla Lobina, Federico Corelli

Am J Drug Alcohol Abuse· November 2022

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Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress.
Antonella Brizzi, Samuele Maramai, Francesca Aiello, Maria Camilla Baratto, Federico Corelli

Int J Mol Sci· November 2022

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Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors.
Marco Paolino, Mariagrazia Rullo, Samuele Maramai, Modesto de Candia, Leonardo Pisani, Federico Corelli

RSC Med Chem· July 2022

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In Silico Multi-Target Approach Revealed Potential Lead Compounds as Scaffold for the Synthesis of Chemical Analogues Targeting SARS-CoV-2.
Alfonso Trezza, Claudia Mugnaini, Federico Corelli, Annalisa Santucci, Ottavia Spiga

Biology (Basel)· March 2022

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Reducing effect of the novel positive allosteric modulator of the GABA receptor, COR659, on binge-like alcohol drinking in male mice and rats.
Irene Lorrai, Chase Shankula, Jorge Marquez Gaytan, Tomoya Kawamura, Paola Maccioni, Federico Corelli

Psychopharmacology (Berl)· January 2022

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Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors.
Diego Fiorucci, Eva Milletti, Francesco Orofino, Antonella Brizzi, Claudia Mugnaini, Federico Corelli

J Biomol Struct Dyn· October 2021

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Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target.
Nastasja Palombi, Annalaura Brai, Martina Gerace, Salvatore Di Maria, Francesco Orofino, Federico Corelli

Curr Med Chem· October 2021

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Has a "Chemical Magic" Opened up New Prospects for Glaucoma?
Federico Corelli

J Med Chem· June 2021

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COR758, a negative allosteric modulator of GABA receptors.
Alessandra Porcu, Rafaela Mostallino, Valeria Serra, Miriam Melis, Valeria Sogos, Federico Corelli

Neuropharmacology· May 2021

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Suppressing effect of the novel positive allosteric modulator of the GABA receptor, COR659, on locomotor hyperactivity induced by different drugs of abuse.
Carla Lobina, Paola Maccioni, Irene Lorrai, Alessandro Zaru, Maria Collu, Federico Corelli

Behav Brain Res· February 2021

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The GABA receptor positive allosteric modulator COR659: In vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives.
Francesca Ferlenghi, Paola Maccioni, Claudia Mugnaini, Antonella Brizzi, Federica Fara, Federico Corelli

Eur J Pharm Sci· December 2020

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Correction to Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo.
Claudia Mugnaini, Magdalena Kostrzewa, Marta Bryk, Ali Mokhtar Mahmoud, Antonella Brizzi, Federico Corelli

J Med Chem· October 2020

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Structure optimization of positive allosteric modulators of GABA receptors led to the unexpected discovery of antagonists/potential negative allosteric modulators.
Claudia Mugnaini, Antonella Brizzi, Rafaela Mostallino, Maria Paola Castelli, Federico Corelli

Bioorg Med Chem Lett· September 2020

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Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo.
Claudia Mugnaini, Magdalena Kostrzewa, Marta Bryk, Ali Mokhtar Mahmoud, Antonella Brizzi, Federico Corelli

J Med Chem· July 2020

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