Publications by authors named "Federico Perche"

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Evaluation of synthetic mRNA with selected UTR sequences and alternative poly(A) tail, and .
Ayoub Medjmedj, Hugo Genon, Dounia Hezili, Albert Ngalle Loth, Rudy Clemençon, Federico Perche

Mol Ther Nucleic Acids· September 2025

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Structural and functional characterization of a histidylated liposome for mRNA delivery.
Albert Ngalle Loth, Manon Maroquenne, Ayoub Medjmedj, Franck Coste, Thomas Bizien, Federico Perche

J Control Release· March 2025

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Messenger RNA Lipid-Based Nanoparticles: Optimization of Formulations in the Lab.
Christophe Delehedde, Ivan Ciganek, Nabila Laroui, Nathalie Rameix, Federico Perche

Methods Mol Biol· May 2024

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DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer.
Geoffrey Casas, Federico Perche, Patrick Midoux, Chantal Pichon, Jean-Marc Malinge

Mol Ther Nucleic Acids· September 2022

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In Cellulo and In Vivo Comparison of Cholesterol, Beta-Sitosterol and Dioleylphosphatidylethanolamine for Lipid Nanoparticle Formulation of mRNA.
Ayoub Medjmedj, Albert Ngalle-Loth, Rudy Clemençon, Josef Hamacek, Chantal Pichon, Federico Perche

Nanomaterials (Basel)· July 2022

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In Vivo bone tissue induction by freeze-dried collagen-nanohydroxyapatite matrix loaded with BMP2/NS1 mRNAs lipopolyplexes.
Pinpin Wang, Federico Perche, Patrick Midoux, Cátia S D Cabral, Virginie Malard

J Control Release· June 2021

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Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles.
Christophe Delehedde, Luc Even, Patrick Midoux, Chantal Pichon, Federico Perche

Pharmaceutics· June 2021

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Nanomedicine-Based Approaches for mRNA Delivery.
Satoshi Uchida, Federico Perche, Chantal Pichon, Horacio Cabral

Mol Pharm· October 2020

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Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation.
Pinpin Wang, Delphine Logeart-Avramoglou, Hervé Petite, Cristine Goncalves, Patrick Midoux, Federico Perche

Acta Biomater· May 2020

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Deciphering the Biological Activities of sp. Aqueous Extract from Stressed Conditions on Breast Cancer: from in Vitro to in Vivo Investigations.
Fatma Elleuch, Patrick Baril, Mohamed Barkallah, Federico Perche, Slim Abdelkafi

Int J Mol Sci· March 2020

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RNA-based therapy for osteogenesis.
Pinpin Wang, Federico Perche, Delphine Logeart-Avramoglou, Chantal Pichon

Int J Pharm· October 2019

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Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine.
Federico Perche, Rudy Clemençon, Kai Schulze, Thomas Ebensen, Carlos A Guzmán

Mol Ther Nucleic Acids· September 2019

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Cardiolipin-Based Lipopolyplex Platform for the Delivery of Diverse Nucleic Acids into Gram-Negative Bacteria.
Federico Perche, Tony Le Gall, Tristan Montier, Chantal Pichon, Jean-Marc Malinge

Pharmaceuticals (Basel)· May 2019

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Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.
Yu Yi, Hyun Jin Kim, Meng Zheng, Peng Mi, Mitsuru Naito, Federico Perche

J Control Release· February 2019

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Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.
Kevin Van der Jeught, Stefaan De Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, Federico Perche

ACS Nano· October 2018

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Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer.
Federico Perche, Satoshi Uchida, Hiroki Akiba, Chin-Yu Lin, Masaru Ikegami

Curr Alzheimer Res· October 2017

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Hypoxia-Responsive Copolymer for siRNA Delivery.
Federico Perche, Swati Biswas, Niravkumar R Patel, Vladimir P Torchilin

Methods Mol Biol· August 2016

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Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles.
Chin-Yu Lin, Federico Perche, Masaru Ikegami, Satoshi Uchida, Kazunori Kataoka

J Control Release· August 2016

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Novel nanostructured lipid carrier co-loaded with doxorubicin and docosahexaenoic acid demonstrates enhanced in vitro activity and overcomes drug resistance in MCF-7/Adr cells.
Samuel V Mussi, Rupa Sawant, Federico Perche, Mônica C Oliveira, Ricardo B Azevedo

Pharm Res· August 2014

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Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs.
Lin Zhu, Federico Perche, Tao Wang, Vladimir P Torchilin

Biomaterials· April 2014

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Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety.
Lin Zhu, Tao Wang, Federico Perche, Anton Taigind, Vladimir P Torchilin

Proc Natl Acad Sci U S A· October 2013

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Octa-arginine-modified pegylated liposomal doxorubicin: an effective treatment strategy for non-small cell lung cancer.
Swati Biswas, Pranali P Deshpande, Federico Perche, Namita S Dodwadkar, Shailendra D Sane

Cancer Lett· July 2013

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Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting.
Federico Perche, Vladimir P Torchilin

J Drug Deliv· March 2013

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Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG-PE micelles in ovarian cancer cell spheroid model.
Federico Perche, Niravkumar R Patel, Vladimir P Torchilin

J Control Release· November 2012

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Cancer cell spheroids as a model to evaluate chemotherapy protocols.
Federico Perche, Vladimir P Torchilin

Cancer Biol Ther· October 2012

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