Publications by authors named "Feipu Yang"

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Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties.
Jiefang Zheng, Yaxin Tian, Jiaxin Cheng, Zhengtao Hu, Junchi Zhang, Feipu Yang, Yang He

Eur J Med Chem· January 2026

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Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates.
Li Xiang, Jishan Qin, Temur Kushatov, Firdavsi Tursunov, Ozod Farmonov, Feipu Yang

J Nat Prod· December 2025

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Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CL inhibitors against SARS-CoV -2.
Samuel Desta Guma, Zhaoyin Zhou, Kang Song, Feipu Yang, Jin Suo

Eur J Med Chem· January 2025

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Structural Similarity in Natural Products Leading to Sample Misidentification: A Case Study of the Bisbenzylisoquinoline Alkaloids Oxyacanthine and Berbamine.
Yan Cheng, Davlat Akramov, Lola Yakhshilikova, Chengwei Zhu, Jie Lu, Feipu Yang

J Nat Prod· January 2025

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Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity.
Jie Lu, Yan Cheng, Yumin Zhang, Yi Wang, Bingqing Xia, Yang He, Feipu Yang

Bioorg Med Chem Lett· November 2024

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Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile.
Jiefang Zheng, Liping Zhou, Xudong Gong, Feipu Yang, Jiaxin Cheng, Yang He

Eur J Med Chem· September 2024

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An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization.
Abdullajon Odilov, Xudong Gong, Hongjian Qin, Emmanuel Mintah Bonku, Fuqiang Zhu, Feipu Yang

J Org Chem· May 2024

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Impurity study of tecovirimat.
Emmanuel Mintah Bonku, Hongjian Qin, Abdullajon Odilov, Safomuddin Abduahadi, Samuel Desta Guma, Feipu Yang

Heliyon· May 2024

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Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from -bromoarylamine and nitriles.
Emmanuel Mintah Bonku, Hongjian Qin, Abdullajon Odilov, Safomuddin Abduahadi, Samuel Desta Guma, Feipu Yang

RSC Adv· February 2024

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Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
Chengcheng Zhao, Xiangrui Jiang, Liyuan Peng, Yan Zhang, Huihui Li, Feipu Yang

J Mol Cell Cardiol· December 2023

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Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir.
Xiangrui Jiang, Haixia Su, Weijuan Shang, Feng Zhou, Yan Zhang, Feipu Yang

Nat Commun· October 2023

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Pharmacokinetics, mass balance, and metabolism of [C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension.
Yi-Fei He, Yin Liu, Jing-Hua Yu, Huan Cheng, Abdullajon Odilov, Fei-Pu Yang

Acta Pharmacol Sin· January 2023

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SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target.
Bingqing Xia, Xurui Shen, Yang He, Xiaoyan Pan, Feng-Liang Liu, Feipu Yang

Cell Res· August 2021

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TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia.
Yu Wang, Yang He, Feipu Yang, Melkamu Alemu Abame, Chunhui Wu

J Pharmacol Exp Ther· July 2021

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Automated design and optimization of multitarget schizophrenia drug candidates by deep learning.
Xiaoqin Tan, Xiangrui Jiang, Yang He, Feisheng Zhong, Xutong Li, Feipu Yang

Eur J Med Chem· October 2020

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Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics.
Wenqiang Shi, Yu Wang, Chunhui Wu, Feipu Yang, Wei Zheng, Yang He

Bioorg Med Chem Lett· April 2020

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Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile.
Chunhui Wu, Yu Wang, Feipu Yang, Wenqiang Shi, Zhen Wang, Yang He

ChemMedChem· December 2019

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Oxidative Aromatization of 3,4-Dihydroquinolin-2(1 H)-ones to Quinolin-2(1 H)-ones Using Transition-Metal-Activated Persulfate Salts.
Weiming Chen, Changliang Sun, Yan Zhang, Tianwen Hu, Fuqiang Zhu, Feipu Yang

J Org Chem· July 2019

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Continuation of structure-activity relationship study of novel benzamide derivatives as potential antipsychotics.
Mingshuo Xu, Shuang Guo, Feipu Yang, Yu Wang, Chunhui Wu, Yang He

Arch Pharm (Weinheim)· April 2019

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Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect.
Mingshuo Xu, Yu Wang, Feipu Yang, Chunhui Wu, Zhen Wang, Yang He

Eur J Med Chem· February 2018

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Synthesis and biological evaluation of a series of novel pyridinecarboxamides as potential multi-receptor antipsychotic drugs.
Mingshuo Xu, Yu Wang, Feipu Yang, Chunhui Wu, Zhen Wang, Yang He

Bioorg Med Chem Lett· February 2018

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Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics.
Hainimu Xiamuxi, Zhen Wang, Jianfeng Li, Yu Wang, Chunhui Wu, Feipu Yang, Yang He

Bioorg Med Chem· September 2017

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[Research progress of antipsychotics].
Fei-pu Yang, Yang He, Zhen Wang, Yu Wang, Xiang-rui Jiang

Yao Xue Xue Bao· December 2016

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Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics.
Feipu Yang, Xiangrui Jiang, Jianfeng Li, Yu Wang, Yongjian Liu, Yang He

Bioorg Med Chem Lett· July 2016

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