Publications by authors named "Felice Elefant"

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Modulating Cognition-Linked Histone Acetyltransferases (HATs) as a Therapeutic Strategy for Neurodegenerative Diseases: Recent Advances and Future Trends.
Huong Anh Mai, Christina M Thomas, Gu Gu Nge, Felice Elefant

Cells· June 2025

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Tip60 HAT activators as therapeutic modulators for Alzheimer's disease.
Akanksha Bhatnagar, Christina M Thomas, Gu Gu Nge, Aprem Zaya, Rohan Dasari, Felice Elefant

Nat Commun· April 2025

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Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control.
Ellen M Armour, Christina M Thomas, Gabrielle Greco, Akanksha Bhatnagar, Felice Elefant

Mol Cell Neurosci· December 2023

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Novel EAAT2 activators improve motor and cognitive impairment in a transgenic model of Huntington's disease.
Akanksha Bhatnagar, Visha Parmar, Nicholas Barbieri, Frank Bearoff, Felice Elefant

Front Behav Neurosci· June 2023

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Tip60's Novel RNA-Binding Function Modulates Alternative Splicing of Pre-mRNA Targets Implicated in Alzheimer's Disease.
Akanksha Bhatnagar, Keegan Krick, Bhanu Chandra Karisetty, Ellen M Armour, Elizabeth A Heller, Felice Elefant

J Neurosci· March 2023

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Cellular response to β-amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics.
Haolin Zhang, Xianghua Li, Xiaoli Wang, Jiayu Xu, Felice Elefant

Animal Model Exp Med· February 2023

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Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain.
Mariah Beaver, Bhanu Chandra Karisetty, Haolin Zhang, Akanksha Bhatnagar, Ellen Armour, Felice Elefant

Epigenetics· July 2022

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Exploring the Alzheimer's disease neuroepigenome: recent advances and future trends.
Haolin Zhang, Felice Elefant

Neural Regen Res· February 2022

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Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration.
Haolin Zhang, Bhanu Chandra Karisetty, Akanksha Bhatnagar, Ellen M Armour, Mariah Beaver, Felice Elefant

Mol Cell Neurosci· December 2020

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Amyloid-β Peptide Impact on Synaptic Function and Neuroepigenetic Gene Control Reveal New Therapeutic Strategies for Alzheimer's Disease.
Bhanu Chandra Karisetty, Akanksha Bhatnagar, Ellen M Armour, Mariah Beaver, Haolin Zhang, Felice Elefant

Front Mol Neurosci· November 2020

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Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases.
Mariah Beaver, Akanksha Bhatnagar, Priyalakshmi Panikker, Haolin Zhang, Renee Snook, Felice Elefant

Sci Rep· October 2020

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Deletion of Glycogen Synthase Kinase-3β in D Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity.
Yan-Chun Li, Priyalakshmi Panikker, Bo Xing, Sha-Sha Yang, Cassandra Alexandropoulos, Felice Elefant

Biol Psychiatry· April 2020

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Hippocampal stimulation promotes intracellular Tip60 dynamics with concomitant genome reorganization and synaptic gene activation.
Ashley Karnay, Bhanu Chandra Karisetty, Mariah Beaver, Felice Elefant

Mol Cell Neurosci· December 2019

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Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration.
Haolin Zhang, Meng Jia, Xue-Wei Wang, Can Ye, Yijing Li, Felice Elefant

Sci Rep· February 2019

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Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition.
Priyalakshmi Panikker, Song-Jun Xu, Haolin Zhang, Jessica Sarthi, Mariah Beaver, Felice Elefant

J Neurosci· May 2018

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Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia.
Yelena Gulchina, Song-Jun Xu, Melissa A Snyder, Felice Elefant, Wen-Jun Gao

J Neurochem· November 2017

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Tip60 HAT Action Mediates Environmental Enrichment Induced Cognitive Restoration.
Songjun Xu, Priyalakshmi Panikker, Sahira Iqbal, Felice Elefant

PLoS One· July 2017

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Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60.
Songjun Xu, Felice Elefant

Fly (Austin)· June 2016

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Epigenetic control of learning and memory in Drosophila by Tip60 HAT action.
Songjun Xu, Rona Wilf, Trisha Menon, Priyalakshmi Panikker, Jessica Sarthi, Felice Elefant

Genetics· December 2014

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A HAT for sleep?: epigenetic regulation of sleep by Tip60 in Drosophila.
Sheila K Pirooznia, Felice Elefant

Fly (Austin)· January 2014

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Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer's disease model.
Sheila K Pirooznia, Jessica Sarthi, Ashley A Johnson, Meridith S Toth, Kellie Chiu, Felice Elefant

PLoS One· April 2013

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Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities.
Sheila K Pirooznia, Felice Elefant

Front Cell Neurosci· April 2013

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Increasing Tip60 HAT levels rescues axonal transport defects and associated behavioral phenotypes in a Drosophila Alzheimer's disease model.
Ashley A Johnson, Jessica Sarthi, Sheila K Pirooznia, William Reube, Felice Elefant

J Neurosci· April 2013

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Epigenetic regulation of axonal growth of Drosophila pacemaker cells by histone acetyltransferase tip60 controls sleep.
Sheila K Pirooznia, Kellie Chiu, May T Chan, John E Zimmerman, Felice Elefant

Genetics· December 2012

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dTip60 HAT activity controls synaptic bouton expansion at the Drosophila neuromuscular junction.
Jessica Sarthi, Felice Elefant

PLoS One· March 2012

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