Publications by authors named "Felix Clanchy"

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IRAK3 is upregulated in rheumatoid arthritis synovium and delays the onset of experimental arthritis.
Federica Borghese, Richard O Williams, Felix I L Clanchy

Front Immunol· May 2025

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Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance.
Felix Il Clanchy, Federica Borghese, Jonas Bystrom, Attila Balog, Henry Penn

J Autoimmun· September 2024

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TNFR2 signalling in inflammatory diseases.
Richard O Williams, Felix Il Clanchy, Yi-Shu Huang, Wen-Yi Tseng, Trevor W Stone

Best Pract Res Clin Rheumatol· May 2024

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Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS).
Joy Ogbechi, Yi-Shu Huang, Felix I L Clanchy, Eirini Pantazi, Louise M Topping

Front Immunol· November 2022

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An integrated cytokine and kynurenine network as the basis of neuroimmune communication.
Trevor W Stone, Felix I L Clanchy, Yi-Shu Huang, Nien-Yi Chiang, L Gail Darlington

Front Neurosci· November 2022

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Standardization of Antigen-Emulsion Preparations for the Induction of Autoimmune Disease Models.
Louise M Topping, Laura Romero-Castillo, Vilma Urbonaviciute, Hans Bolinsson, Felix I Clanchy

Front Immunol· July 2022

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Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression.
Felix I L Clanchy, Federica Borghese, Jonas Bystrom, Attila Balog, Henry Penn

J Autoimmun· April 2022

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Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?
Felix I L Clanchy, Yi-Shu Huang, Joy Ogbechi, L Gail Darlington, Richard O Williams

Front Immunol· April 2022

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Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis.
Yi-Shu Huang, Wen-Yi Tseng, Felix I L Clanchy, Louise M Topping, Joy Ogbechi

Proc Natl Acad Sci U S A· May 2021

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IDO and Kynurenine Metabolites in Peripheral and CNS Disorders.
Yi-Shu Huang, Joy Ogbechi, Felix I Clanchy, Richard O Williams, Trevor W Stone

Front Immunol· March 2021

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TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis.
Felix I L Clanchy, Federica Borghese, Jonas Bystrom, Attila Balog, Henry Penn

J Autoimmun· March 2021

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TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20.
Mohammed Al-Bogami, Jonas Bystrom, Felix Clanchy, Taher E Taher, Pamela Mangat

Rheumatology (Oxford)· February 2021

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Rationale for Early Detection of Translocation-Associated Sarcoma Biomarkers in Liquid Biopsy.
Felix I L Clanchy

Cancers (Basel)· February 2021

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Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo .
Susan Aungier, Alison J Cartwright, Anja Schwenzer, Jennifer Marshall, Mike R Dyson, Felix Il Clanchy

Ann Rheum Dis· April 2020

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IDO activation, inflammation and musculoskeletal disease.
Joy Ogbechi, Felix I Clanchy, Yi-Shu Huang, Louise M Topping, Trevor W Stone

Exp Gerontol· March 2020

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TNF receptor 2 signaling prevents DNA methylation at the promoter and prevents pathogenic conversion of regulatory T cells.
Wen-Yi Tseng, Yi-Shu Huang, Felix Clanchy, Kay McNamee, Dany Perocheau

Proc Natl Acad Sci U S A· October 2019

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Ibudilast Inhibits Chemokine Expression in Rheumatoid Arthritis Synovial Fibroblasts and Exhibits Immunomodulatory Activity in Experimental Arthritis.
Felix I L Clanchy, Richard O Williams

Arthritis Rheumatol· May 2019

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Targeting early changes in the synovial microenvironment: a new class of immunomodulatory therapy?
Susan R Aungier, Alison J Cartwright, Anja Schwenzer, Jennifer L Marshall, Michael R Dyson, Felix Il Clanchy

Ann Rheum Dis· February 2019

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Functional and phenotypic heterogeneity of Th17 cells in health and disease.
Jonas Bystrom, Felix I L Clanchy, Taher E Taher, Mohammed Al-Bogami, Voon H Ong

Eur J Clin Invest· January 2019

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T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis.
Maria Arshad, Attya Bhatti, Peter John, Fazal Jalil, Federica Borghese, Felix I L Clanchy

Cytokine· April 2018

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TNFR signalling and its clinical implications.
Wen-Yi Tseng, Yi-Shu Huang, Hsi-Hsien Lin, Shue-Fen Luo, Fiona McCann, Felix Clanchy

Cytokine· January 2018

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Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF T Lymphocytes.
Jonas Bystrom, Felix I Clanchy, Taher E Taher, Mohammed M Al-Bogami, Hawzheen A Muhammad

Clin Rev Allergy Immunol· October 2017

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Harnessing the Therapeutic Potential of Th17 Cells.
Jonas Bystrom, Taher E Taher, M Sherwan Muhyaddin, Felix I Clanchy, Pamela Mangat

Mediators Inflamm· June 2016

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High-Affinity Fc Receptor Expression Indicates Relative Immaturity in Human Monocytes.
Felix I L Clanchy

J Interferon Cytokine Res· May 2016

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The development of macrophages from human CD34+ haematopoietic stem cells in serum-free cultures is optimized by IL-3 and SCF.
Felix I L Clanchy, John A Hamilton

Cytokine· January 2013

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