Publications by authors named "Felix Scheuplein"

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Evaluation of STK17B as a cancer immunotherapy target utilizing highly potent and selective small molecule inhibitors.
Felix Scheuplein, Florian Renner, John E Campbell, Robert Campbell, Chris De Savi

Front Immunol· November 2024

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Cancer Immunotherapeutic Potential of NKTT320, a Novel, Invariant, Natural Killer T Cell-Activating, Humanized Monoclonal Antibody.
Nishant P Patel, Peng Guan, Devika Bahal, Tanwir Hashem, Felix Scheuplein

Int J Mol Sci· June 2020

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The role of iNKT cells on the phenotypes of allergic airways in a mouse model.
Lennart K A Lundblad, Nazey Gülec, Matthew E Poynter, Victoria L DeVault, Oliver Dienz, Felix Scheuplein

Pulm Pharmacol Ther· August 2017

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Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo.
Felix Scheuplein, Deanna J Lamont, Matthew E Poynter, Jonathan E Boyson, David Serreze

PLoS One· June 2016

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A humanized monoclonal antibody specific for invariant Natural Killer T (iNKT) cells for in vivo depletion.
Felix Scheuplein, Abraham Thariath, Susan Macdonald, Alemseged Truneh, Robert Mashal

PLoS One· June 2014

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Transgenic overexpression of toxin-related ecto-ADP-ribosyltransferase ART2.2 sensitizes T cells but not B cells to NAD-induced cell death.
Peter Bannas, Felix Scheuplein, Lennart Well, Irm Hermans-Borgmeyer, Friedrich Haag

Mol Immunol· September 2011

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Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice.
Yi-Guang Chen, Felix Scheuplein, John P Driver, Amanda A Hewes, Peter C Reifsnyder

J Immunol· April 2011

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A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes.
Felix Scheuplein, Björn Rissiek, John P Driver, Yi-Guang Chen, Friedrich Koch-Nolte

J Autoimmun· March 2010

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Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette.
John P Driver, Felix Scheuplein, Yi-Guang Chen, Alexandra E Grier, S Brian Wilson

Diabetes· February 2010

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Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.
Janusz Wesolowski, Vanina Alzogaray, Jan Reyelt, Mandy Unger, Karla Juarez, Felix Scheuplein

Med Microbiol Immunol· August 2009

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Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7.
Sahil Adriouch, Felix Scheuplein, Robert Bähring, Michel Seman, Olivier Boyer

Purinergic Signal· June 2009

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NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells.
Felix Scheuplein, Nicole Schwarz, Sahil Adriouch, Christian Krebs, Peter Bannas

J Immunol· March 2009

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Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.
Yi-Guang Chen, Felix Scheuplein, Melissa A Osborne, Shirng-Wern Tsaih, Harold D Chapman

Diabetes· December 2008

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Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo.
Friedrich Koch-Nolte, Jan Reyelt, Britta Schössow, Nicole Schwarz, Felix Scheuplein

FASEB J· November 2007

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Extracellular NAD and ATP: Partners in immune cell modulation.
Friedrich Haag, Sahil Adriouch, Anette Braß, Caroline Jung, Sina Möller, Felix Scheuplein

Purinergic Signal· March 2007

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ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells.
Friedrich Koch-Nolte, Sahil Adriouch, Peter Bannas, Christian Krebs, Felix Scheuplein

Ann Med· June 2006

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Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.
Jing Chen, Yi-Guang Chen, Peter C Reifsnyder, William H Schott, Chul-Ho Lee, Felix Scheuplein

J Immunol· April 2006

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"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells.
Jing Chen, Peter C Reifsnyder, Felix Scheuplein, William H Schott, Maria Mileikovsky

Mamm Genome· October 2005

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Triggering of T-cell apoptosis by toxin-related ecto-ADP-ribosyltransferase ART2.
Felix Scheuplein, Sahahil Adriouch, Gustavo Glowacki, Friedrich Haag, Michel Seman

Ann N Y Acad Sci· December 2003

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NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.
Michel Seman, Sahil Adriouch, Felix Scheuplein, Christian Krebs, Dunja Freese

Immunity· October 2003

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