Publications by authors named "Fengxin Zhu"

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Gene signature-guided drug screening identified narciclasine as a potential therapeutic for interstitial fibrosis of the kidney.
An Xiao, Xiaoer Chen, Jingyi Ma, Xiaomei Chen, Tantan Long, Fengxin Zhu

Kidney Int· July 2025

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Renal tubular GSDME protects cisplatin nephrotoxicity by impeding OGT-STAT3-S100A7A axis in male mice.
Qingzhou Chen, Pengxiao Sun, Jiaxin Zhou, Tantan Long, An Xiao, Zhuoliang Liu, Fengxin Zhu

Nat Commun· July 2025

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Condensation of cellular prion protein promotes renal fibrosis through the TBK1-IRF3 signaling axis.
Tantan Long, Yumei Lu, Yuanyuan Ma, Yandong Song, Xiaoping Yi, Zhuoliang Liu, Fengxin Zhu

Sci Transl Med· April 2025

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Renal tubular S100A7a impairs fatty acid oxidation and exacerbates renal fibrosis via both intracellular and extracellular pathway.
Pengxiao Sun, Qingzhou Chen, Xiaomei Chen, Jiaxin Zhou, Tantan Long, Fengxin Zhu

Biochim Biophys Acta Mol Basis Dis· March 2025

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Retraction: QiShenYiQi Attenuates Renal Interstitial Fibrosis by Blocking the Activation of β-Catenin.
Zhanmei Zhou, Zheng Hu, Mei Li, Fengxin Zhu, Hao Zhang

PLoS One· January 2024

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Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells.
Zhiyuan Su, Zhuoliang Liu, Wenjing Lei, Kai Xia, An Xiao, Fengxin Zhu

Cell Biol Toxicol· December 2023

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Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis.
Wenjing Lei, Zhuoliang Liu, Zhiyuan Su, Panpan Meng, Chun Zhou, Fengxin Zhu

J Hematol Oncol· July 2023

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Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
Shihui Xu, Xiaobing Yang, Qingzhou Chen, Zhuoliang Liu, Ying Chen, Fengxin Zhu

EBioMedicine· December 2022

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Dietary choline, gut microbe- generated trimethylamine-N- oxide, aggravates chronic kidney disease-induced cardiac dysfunction by inhibiting hypoxia-induced factor 1α.
Feifei Xie, Xin Zhen, Zhuoliang Liu, Xiaomei Chen, Zhuanhua Liu, Fengxin Zhu

Front Physiol· November 2022

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Targeted inhibition of ZAK ameliorates renal interstitial fibrosis.
Shuangshuang Shu, Han Liu, Jianzhang Yang, Haie Tang, Hao Li, Zhuoliang Liu, Fengxin Zhu

Transl Res· August 2022

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NUMB facilitates autophagy initiation through targeting SCF complex.
Hao Li, Shuangshuang Shu, Miaomiao Zhou, Ying Chen, An Xiao, Fengxin Zhu

Cell Death Differ· July 2022

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Gut microbial metabolite TMAO increases peritoneal inflammation and peritonitis risk in peritoneal dialysis patients.
Lei Zhang, Feifei Xie, Haie Tang, Xinrong Zhang, Jianxia Hu, Fengxin Zhu

Transl Res· February 2022

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Trimethylamine-N-Oxide Aggravates Kidney Injury via Activation of p38/MAPK Signaling and Upregulation of HuR.
Yunshi Lai, Haie Tang, Xinrong Zhang, Zhanmei Zhou, Miaomiao Zhou, Fengxin Zhu

Kidney Blood Press Res· February 2022

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Tubular Numb promotes renal interstitial fibrosis via modulating HIF-1α protein stability.
Fengxin Zhu, Hao Li, Tantan Long, Miaomiao Zhou, Jiao Wan

Biochim Biophys Acta Mol Basis Dis· May 2021

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Nicotinamide Supplementation Attenuates Renal Interstitial Fibrosis via Boosting the Activity of Sirtuins.
Xin Zhen, Shaowu Zhang, Feifei Xie, Miaomiao Zhou, Zheng Hu, Fengxin Zhu

Kidney Dis (Basel)· May 2021

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A U-shaped association between serum betaine and incident risk of first ischemic stroke in hypertensive patients.
Liling Xie, Bo-Xin Zhao, Jiajun Luo, Youbao Li, Fengxin Zhu

Clin Nutr· August 2020

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Withdrawal: A novel interaction between the SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1 engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility.
Guo Zhang, Xia Chen, Fanghua Qiu, Fengxin Zhu, Wenjing Lei

J Biol Chem· December 2019

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Numb Depletion Promotes Drp1-Mediated Mitochondrial Fission and Exacerbates Mitochondrial Fragmentation and Dysfunction in Acute Kidney Injury.
Ze Liu, Hao Li, Jianqun Su, Shihui Xu, Fengxin Zhu

Antioxid Redox Signal· May 2019

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Hyperhomocysteinemia Accelerates Acute Kidney Injury to Chronic Kidney Disease Progression by Downregulating Heme Oxygenase-1 Expression.
Shuang Li, Bingbing Qiu, Hong Lu, Yunshi Lai, Jixing Liu, Fengxin Zhu

Antioxid Redox Signal· May 2019

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Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.
Jing Nie, Liling Xie, Bo-Xin Zhao, Youbao Li, Bingbing Qiu, Fengxin Zhu

Stroke· September 2018

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Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury.
Yanjun Long, Xin Zhen, Fengxin Zhu, Zheng Hu, Wenjing Lei

Int J Biol Sci· November 2017

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The antihelmenthic phosphate niclosamide impedes renal fibrosis by inhibiting homeodomain-interacting protein kinase 2 expression.
Xiaoyan Chang, Xin Zhen, Jixing Liu, Xiaomei Ren, Zheng Hu, Fengxin Zhu

Kidney Int· September 2017

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QiShenYiQi Attenuates Renal Interstitial Fibrosis by Blocking the Activation of β-Catenin.
Zhanmei Zhou, Zheng Hu, Mei Li, Fengxin Zhu, Hao Zhang

PLoS One· August 2017

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Hepatitis B virus X protein promotes renal epithelial-mesenchymal transition in human renal proximal tubule epithelial cells through the activation of NF-κB.
Mei Li, Liping Hu, Fengxin Zhu, Zhangmei Zhou, Jianwei Tian

Int J Mol Med· August 2016

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Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M.
Fengxin Zhu, Wei Liu, Tang Li, Jiao Wan, Jianwei Tian

Oncotarget· May 2016

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