Publications by authors named "Fengyuan Che"

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Targeting the FBXO5-DOK6 axis to overcome temozolomide resistance in glioblastoma via proteasome-cytomechanics regulation.
Chao Wang, Mengqi Wang, Zhenye Zhu, Huang Tan, Danchen Su, Fengyuan Che

Cancer Lett· December 2025

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Glucagon-like peptide-1 receptor agonist in large vessel occlusion treated by reperfusion therapy-a phase 2 randomized trial.
Hao Wang, Ho Ko, Thomas W Leung, Junzhe Huang, Junjie Sai, Tom Cheung, Fengyuan Che

Nat Commun· December 2025

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Deleterious, protein-altering variants in GSPT2 are putatively associated with an X-linked neurodevelopmental disorder with intellectual disability, language impairment, autism and epilepsy.
Yuda Wei, Kai Liu, Changrui Mi, Jing Yu, Ruopeng Sun, Chen Zhao, Chengcheng Gai, Fengyuan Che

Genet Med· December 2025

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Renal dysfunction and outcomes for thrombolysis-treated stroke beyond 4.5 hours: Trace-Ⅲ post hoc analysis.
Lixia Zong, Liyuan Wang, Aoming Jin, Yujie Ma, Xueyan Feng, Fengyuan Che

J Stroke Cerebrovasc Dis· October 2025

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Pilot research on predicting the sub-volume with high risk of tumor recurrence inside peritumoral edema using the ratio-maxiADC/meanADC from the advanced MRI.
Jinling Zhang, Haobin Liu, Yuxiao Wu, Jian Zhu, Yuting Wang, Fengyuan Che

Discov Oncol· September 2025

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Qinglongyi nanoparticles alleviate neuroinflammation and promote neuronal survival by inhibiting neuronal ferroptosis in intracerebral hemorrhage.
Tao Yan, Guiqiong Kang, Yun Meng, Liping Zhang, Qing Jiang, Fengyuan Che

Int Immunopharmacol· June 2025

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The soluble epoxide hydrolase inhibitor TPPU alleviates Aβ-mediated neuroinflammatory responses in Drosophila melanogaster and cellular models of alzheimer's disease.
Xiaowen Sun, Hongxiang Liu, Wei Li, Lin Li, Qian Tian, Fengyuan Che

J Inflamm (Lond)· June 2025

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Tenecteplase compared to alteplase before mechanical thrombectomy enhances 1-h recanalization and reduces disability in large-vessel occlusion.
Lu Wang, Jialu Li, Xiao Wu, Lulan Li, Xueqiao Jiao, Fengyuan Che

J Neurol· April 2025

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Repurposing of epalrestat for neuroprotection in parkinson's disease via activation of the KEAP1/Nrf2 pathway.
Huafang Jia, Mengru Liu, Hong Jiang, Zhen Qiao, Kaiyue Ren, Xi Chen, Fengyuan Che

J Neuroinflammation· April 2025

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Exploring TβRI inhibitors from Arenaria kansuensis based on 3D-QSAR, molecular docking and molecular dynamics simulation methods and its anti-pulmonary fibrosis molecular mechanism validation.
Na Shen, Ziyao Shao, Huawei Xin, Fengyuan Che, Yulei Cui

J Ethnopharmacol· January 2025

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The role of lipid metabolism in cognitive impairment.
Meifang Xu, Liyuan Wang, Yun Meng, Guiqiong Kang, Qing Jiang, Fengyuan Che

Arq Neuropsiquiatr· January 2025

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Abnormal H3K4 enzyme catalytic activity and neuronal morphology caused by ASH1L mutations in individuals with Tourette syndrome.
Cheng Zhang, Wenmiao Liu, Lulu Xu, Shiguo Liu, Fengyuan Che

Eur Child Adolesc Psychiatry· November 2024

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Tenecteplase vs Alteplase for Patients With Acute Ischemic Stroke: The ORIGINAL Randomized Clinical Trial.
Xia Meng, Shuya Li, Hongguo Dai, Guozhi Lu, Weiwei Wang, Fengyuan Che

JAMA· November 2024

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Traditional Chinese medicine FYTF-919 (Zhongfeng Xingnao oral prescription) for the treatment of acute intracerebral haemorrhage: a multicentre, randomised, placebo-controlled, double-blind, clinical trial.
Jianwen Guo, Xiaoying Chen, Manli Wu, Dou Wang, Yang Zhao, Fengyuan Che, Yajie Chen

Lancet· November 2024

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Clinical and genetic analysis of 23 Chinese children with epilepsy associated with KCNQ2 gene mutations.
Xixi Yu, Fengyuan Che, Xin Zhang, Li Yang, Liping Zhu

Epilepsia Open· October 2024

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Efficacy and Safety of Chinese Herbal Medicine in Patients with Acute Intracerebral Hemorrhage: Protocol for a Randomized Placebo-Controlled Double-Blinded Multicenter Trial.
Yang Zhao, Wanzhen Cui, Tingting Xie, Kai Zhao, Yunke Li, Chen Xiaoying, Yanjia Chen, Yue Chen, Fengyuan Che

Cerebrovasc Dis· September 2024

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Association of inflammation/nutrition-based indicators with Parkinson's disease and mortality.
Huafang Jia, Kaixiang Yin, Jihu Zhao, Fengyuan Che

Front Nutr· September 2024

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Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy.
Yunyun Xiong, Bruce C V Campbell, Lee H Schwamm, Xia Meng, Aoming Jin, Fengyuan Che

N Engl J Med· July 2024

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Reteplase versus Alteplase for Acute Ischemic Stroke.
Shuya Li, Hong-Qiu Gu, Hao Li, Xuechun Wang, Aoming Jin, Fengyuan Che

N Engl J Med· June 2024

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Epigenetic alterations and advancement of lymphoma treatment.
Shuhui Zhuang, Zhaobo Yang, Zhuangzhuang Cui, Yuanyuan Zhang, Fengyuan Che

Ann Hematol· May 2024

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Surfeit Locus Protein 4 as a Novel Target for Therapeutic Intervention in Cerebral Ischemia-Reperfusion Injury.
Wenjie Hu, Xiangyi Kong, Yu Cui, Hui Wang, Jingchen Gao, Shujun Chen, Fengyuan Che

Mol Neurobiol· April 2024

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Cathodal bilateral transcranial direct-current stimulation regulates selenium to confer neuroprotection after rat cerebral ischaemia-reperfusion injury.
Hui Wang, Wenlong Ma, Wenjie Hu, Xiaohua Li, Na Shen, Jingchen Gao, Fengyuan Che, Juan Chen

J Physiol· March 2024

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Upregulation of mitochondrial PGK1 by ROS-TBC1D15 pathway promotes neuronal death after oxygen-glucose deprivation/reoxygenation injury.
Songfeng Chen, Hui Wang, Juan Chen, Jing Cheng, Jingchen Gao, Shujun Chen, Fengyuan Che

Brain Res· February 2024

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Exploring the anti-glioma mechanism of the active components of Cortex Periplocae based on network pharmacology and iTRAQ proteomics in vitro.
Jing Huan, Cui-Ping You, Yu-Cheng Lu, Feng-Yuan Che

Adv Clin Exp Med· November 2023

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FLAIR-hyperintense lesions in anti-MOG-associated encephalitis with seizures overlaying anti-N-methyl-D-aspartate receptor encephalitis: A case report.
Qingxi Fu, Guangying Wang, Fengyuan Che, Dong Li, Shougang Wang

Medicine (Baltimore)· November 2023

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