Publications by authors named "Fernand-Pierre Gendron"

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Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors.
Marie-Edith Nepveu-Traversy, Malihe Hassanzadeh, Laurent Bruneau-Cossette, Élie Besserer-Offroy, Rebecca Brouillette, Fernand-Pierre Gendron

Nat Commun· December 2025

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Ligand-dependent intracellular trafficking of the G protein-coupled P2Y receptor.
Mélissa Girard, Steve Dagenais Bellefeuille, Émilie Eiselt, Guillaume Arguin, Jean-Michel Longpré, Fernand-Pierre Gendron

Biochim Biophys Acta Mol Cell Res· June 2023

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The expression of P2Y receptor promotes the quality of mucus in colitic mice.
Morgane Placet, Caroline M Molle, Guillaume Arguin, Sameh Geha, Fernand-Pierre Gendron

FEBS J· September 2021

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A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.
Muhammad Sohail, Lulzim Shkreta, Johanne Toutant, Safwat Rabea, Jean-Philippe Babeu, Fernand-Pierre Gendron

NAR Cancer· June 2021

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Expression and function of the P2X7 receptor in human osteoblasts: The role of NFATc1 transcription factor.
Leticia Scussel Bergamin, Letizia Penolazzi, Elisabetta Lambertini, Simonetta Falzoni, Alba Clara Sarti, Fernand-Pierre Gendron

J Cell Physiol· January 2021

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The P2Y receptor signals through Gα /Ca /PKCα and Gα /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
Mélissa Girard, Steve Dagenais Bellefeuille, Émilie Eiselt, Rebecca Brouillette, Morgane Placet, Fernand-Pierre Gendron

J Cell Physiol· December 2020

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The expression of the P2Y receptor is regulated at the transcriptional level by p53.
Caroline M Molle, Guillaume Arguin, Charlotte Jemfer, Morgane Placet, Steve Dagenais Bellefeuille, Fernand-Pierre Gendron

Biochem Biophys Res Commun· April 2020

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Reviewing the role of P2Y receptors in specific gastrointestinal cancers.
Steve Dagenais Bellefeuille, Caroline M Molle, Fernand-Pierre Gendron

Purinergic Signal· December 2019

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Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.
Molhm Nassir, Julie Pelletier, Uri Arad, Guillaume Arguin, Netaly Khazanov, Fernand-Pierre Gendron

Eur J Med Chem· December 2019

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P2Y Receptor Functions in Cancer: A Perspective in the Context of Colorectal Cancer.
Fernand-Pierre Gendron, Morgane Placet, Guillaume Arguin

Adv Exp Med Biol· June 2018

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The G protein-coupled P2Y₆ receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis.
Morgane Placet, Guillaume Arguin, Caroline M Molle, Jean-Philippe Babeu, Christine Jones, Fernand-Pierre Gendron

Biochim Biophys Acta Mol Basis Dis· May 2018

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Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-P-Dithiophosphate Analogues.
Vadim Zelikman, Julie Pelletier, Luba Simhaev, Aviad Sela, Fernand-Pierre Gendron

J Med Chem· May 2018

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The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis.
Guillaume Arguin, Jean-François Bourzac, Morgane Placet, Caroline M Molle, Michel Paquette, Fernand-Pierre Gendron

Sci Rep· October 2017

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Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.
David Lepage, Élise Bélanger, Christine Jones, Sarah Tremblay, Joannie M Allaire, Fernand-Pierre Gendron

Sci Rep· November 2016

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Multidrug Resistance-Associated Protein 2 Expression Is Upregulated by Adenosine 5'-Triphosphate in Colorectal Cancer Cells and Enhances Their Survival to Chemotherapeutic Drugs.
Valérie Vinette, Morgane Placet, Guillaume Arguin, Fernand-Pierre Gendron

PLoS One· May 2016

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Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists.
Diana Meltzer, Ophir Ethan, Guillaume Arguin, Yael Nadel, Ortal Danino, Fernand-Pierre Gendron

Bioorg Med Chem· September 2015

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C/EBPβ regulates P2X7 receptor expression in response to glucose challenge in intestinal epithelial cells.
Maude S Bilodeau, Guillaume Arguin, Fernand-Pierre Gendron

Biochem Cell Biol· February 2015

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The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction.
Ashleigh Hansen, Laurie Alston, Sarah E Tulk, L Patrick Schenck, Michael E Grassie, Fernand-Pierre Gendron

PLoS One· January 2015

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Shuttling of information between the mucosal and luminal environment drives intestinal homeostasis.
Claude Asselin, Fernand-Pierre Gendron

FEBS Lett· November 2014

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The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.
Naomie Turgeon, Julie Moore Gagné, Mylène Blais, Fernand-Pierre Gendron, François Boudreau

Am J Physiol Gastrointest Liver Physiol· April 2014

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P2Y2 receptor promotes intestinal microtubule stabilization and mucosal re-epithelization in experimental colitis.
Emilie Degagné, Jade Degrandmaison, Djordje M Grbic, Valérie Vinette, Guillaume Arguin, Fernand-Pierre Gendron

J Cell Physiol· January 2013

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Glucose transporter 2 expression is down regulated following P2X7 activation in enterocytes.
Jean-François Bourzac, Karine L'Ériger, Jean-François Larrivée, Guillaume Arguin, Maude S Bilodeau, Fernand-Pierre Gendron

J Cell Physiol· January 2013

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UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety.
Tamar Ginsburg-Shmuel, Michael Haas, Djordje Grbic, Guillaume Arguin, Yael Nadel, Fernand-Pierre Gendron

Bioorg Med Chem· September 2012

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P2Y6 receptor contributes to neutrophil recruitment to inflamed intestinal mucosa by increasing CXC chemokine ligand 8 expression in an AP-1-dependent manner in epithelial cells.
Djordje M Grbic, Émilie Degagné, Jean-François Larrivée, Maude S Bilodeau, Valérie Vinette, Fernand-Pierre Gendron

Inflamm Bowel Dis· August 2012

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P2Y(2) receptor expression is regulated by C/EBPβ during inflammation in intestinal epithelial cells.
Emilie Degagné, Naomie Turgeon, Julie Moore-Gagné, Claude Asselin, Fernand-Pierre Gendron

FEBS J· August 2012

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