Publications by authors named "Fernando Goldbaum"

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Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA YOLK) administered by parenteral or mucosal routes against Brucella ovis in rams.
María Celeste Moran, Agostina Tammone Santos, Paula Dominguez, Lucila Moriones, María Victoria Nieto Farias, Fernando Alberto Goldbaum

Vet Immunol Immunopathol· September 2025

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Monitoring Dynamic Conformations of a Single Fluorescent Molecule Inside a Protein Cavity.
Santiago Sosa, Alan M Szalai, Lucía F Lopez, Juan Manuel Prieto, Cecilia Zaza, Fernando A Goldbaum

Small Methods· August 2025

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Open-label, controlled, phase 2 clinical trial assessing the safety, efficacy, and pharmacokinetics of INM004 in pediatric patients with Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome.
Alicia Fayad, Iliana Principi, Alejandro Balestracci, Laura Alconcher, Paula Coccia, Fernando Goldbaum

Pediatr Nephrol· June 2025

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Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome.
Alejandro Ezequiel Cristófalo, Arvind Sharma, María Laura Cerutti, Kedar Sharma, Roberto Melero, Fernando Alberto Goldbaum

Protein Sci· June 2025

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INM004: Polyclonal Neutralizing Antibodies Against Shiga Toxin as a Treatment for Hemolytic Uremic Syndrome.
Marta Rivas, Mariana Pichel, Vanesa Zylberman, Mariana Colonna, Marina Valerio, Fernando Alberto Goldbaum

Toxins (Basel)· June 2025

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A phase I study to evaluate the safety, tolerance and pharmacokinetics of anti-Shiga toxin hyperimmune equine F (ab') fragments in healthy volunteers.
Yanina Hiriart, Paula Scibona, Augusto Ferraris, Waldo H Belloso, Valeria Beruto, Fernando Goldbaum

Br J Clin Pharmacol· April 2024

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Surveillance of Shiga toxin-producing Escherichia coli associated bloody diarrhea in Argentina.
Marta Rivas, Mariana Pichel, Mariana Colonna, Adrián López Casanello, Laura F Alconcher, Fernando Goldbaum

Rev Argent Microbiol· December 2023

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Improvement of Cellulomonas fimi endoglucanase CenA by multienzymatic display on a decameric structural scaffold.
Matías R Iglesias Rando, Natalia Gorojovsky, Vanesa Zylberman, Fernando A Goldbaum, Patricio O Craig

Appl Microbiol Biotechnol· July 2023

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A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers.
Gabriela Llauger, Roberto Melero, Demián Monti, Gabriela Sycz, Cristián Huck-Iriart, Fernando A Goldbaum

mBio· April 2023

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Safety and effectiveness of RBD-specific polyclonal equine F(ab´)2 fragments for the treatment of hospitalized patients with severe Covid-19 disease: A retrospective cohort study.
Diego H Farizano Salazar, Fernando Achinelli, Mariana Colonna, Lucía Pérez, Analía A Giménez, Fernando A Goldbaum

PLoS One· September 2022

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Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA) administered by parenteral or mucosal routes against Brucella ovis in BALB/c mice.
María Celeste Moran, María Paula Dominguez, Angel Ricardo Bence, Marcelo Gastón Rodriguez, Fernando Alberto Goldbaum

Res Vet Sci· July 2022

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Development of high-affinity nanobodies specific for Na1.4 and Na1.5 voltage-gated sodium channel isoforms.
Lakshmi Srinivasan, Vanina Alzogaray, Dakshnamurthy Selvakumar, Sara Nathan, Jesse B Yoder, Fernando A Goldbaum

J Biol Chem· April 2022

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Non-clinical safety assessment and in vivo biodistribution of CoviFab, an RBD-specific F(ab')2 fragment derived from equine polyclonal antibodies.
Facundo Salinas, Belkis E Marelli, Santiago Sanguineti, Fernando Goldbaum, Luciana Muñoz

Toxicol Appl Pharmacol· January 2022

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Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.
Lisandro H Otero, Sabrina Foscaldi, Giuliano T Antelo, Germán L Rosano, Serena Sirigu, Fernando A Goldbaum

Sci Adv· November 2021

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Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms.
Valeria Conforte, Lisandro Horacio Otero, Laila Toum, Serena Sirigu, Giuliano Tomás Antelo, Fernando Alberto Goldbaum

FEBS J· October 2021

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RBD-specific polyclonal F(ab´) fragments of equine antibodies in patients with moderate to severe COVID-19 disease: A randomized, multicenter, double-blind, placebo-controlled, adaptive phase 2/3 clinical trial.
Gustavo Lopardo, Waldo H Belloso, Esteban Nannini, Mariana Colonna, Santiago Sanguineti, Fernando Goldbaum

EClinicalMedicine· April 2021

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Dimer Asymmetry and Light Activation Mechanism in Blue-Light Sensor Histidine Kinase.
Jimena Rinaldi, Ignacio Fernández, Heewhan Shin, Gabriela Sycz, Semini Gunawardana, Fernando A Goldbaum

mBio· April 2021

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Polymeric antigen BLSOmp31 formulated with class B CpG-ODN in a nanostructure (BLSOmp31/CpG-ODN/Coa-ASC16) administered by parenteral or mucosal routes confers protection against Brucella ovis in Balb/c mice.
María Celeste Moran, Angel Ricardo Bence, María Fernanda Sánchez Vallecillo, Claudia María Lützelschwab, Marcelo Gastón Rodriguez, Fernando Alberto Goldbaum

Res Vet Sci· March 2021

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A Spectroscopy-based Methodology for Rapid Screening and Characterization of Phytochrome Photochemistry in Search of Pfr-favored Variants.
Giuliano Tomás Antelo, Maximiliano Sánchez-Lamas, Fernando Alberto Goldbaum, Lisandro Horacio Otero, Hernán Ruy Bonomi

Photochem Photobiol· November 2020

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Crystal structures of peanut lectin in the presence of synthetic β-N- and β-S-galactosides disclose evidence for the recognition of different glycomimetic ligands.
Alejandro J Cagnoni, Emiliano D Primo, Sebastián Klinke, María E Cano, Walter Giordano, Fernando A Goldbaum

Acta Crystallogr D Struct Biol· November 2020

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Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59.
Leonardo Pellizza, José L López, Susana Vázquez, Gabriela Sycz, Beatriz G Guimarães, Fernando A Goldbaum

J Struct Biol· October 2020

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Development of a hyperimmune equine serum therapy for COVID-19 in Argentina.
Vanesa Zylberman, Santiago Sanguineti, Andrea V Pontoriero, Sandra V Higa, María L Cerutti, Fernando A Goldbaum

Medicina (B Aires)· August 2020

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Effect of UVB solar irradiation on Laccase enzyme: evaluation of the photooxidation process and its impact over the enzymatic activity for pollutants bioremediation.
R Daniel Cacciari, Agustina Reynoso, Santiago Sosa, Facundo Parodi, Fernando A Goldbaum

Amino Acids· July 2020

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Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein.
Nicolas Torres, María Victoria Regge, Florencia Secchiari, Adrián David Friedrich, Raúl Germán Spallanzani, Fernando Alberto Goldbaum

J Immunother Cancer· June 2020

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Development and Evaluation of a Novel VHH-Based Immunocapture Assay for High-Sensitivity Detection of Shiga Toxin Type 2 (Stx2) in Stool Samples.
Luciano J Melli, Vanesa Zylberman, Yanina Hiriart, Constanza E Lauche, Ariela Baschkier, Fernando A Goldbaum

J Clin Microbiol· February 2020

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