Publications by authors named "Fernando Muzzio"

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Current state of machine learning implementation in pharmaceutical process modeling for oral solid dosage forms.
Maryam Rezaeizadeh, Sonia M Razavi, Fernando J Muzzio

Int J Pharm· December 2025

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High-dose modified-release formulation of a poorly soluble drug via twin-screw melt coating and granulation.
Shashwat Gupta, Thamer Omar, Qiushi Zhou, James Scicolone, Gerardo Callegari, Fernando Muzzio

Int J Pharm· February 2025

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Real-time monitoring of small changes in powder blends and ejected tablets in a low-dose formulation with 1 %w/w of active pharmaceutical ingredient using Raman and near-infrared spatially resolved spectroscopy within a tablet press.
Carlos A Ortega-Zúñiga, Andrés D Román-Ospino, Shashwat Gupta, Thamer Omar, Yukteshwar Baranwal, Fernando J Muzzio

Int J Pharm· February 2025

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Statistical data treatment for residence time distribution studies in pharmaceutical manufacturing.
Pooja Bhalode, Sonia M Razavi, Huayu Tian, Andres Roman-Ospino, James Scicolone, Fernando J Muzzio

Int J Pharm· May 2024

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Accelerating Process Development and Product Formulation.
Mauricio Futran, Fernando Muzzio, Bikash Chatterjee

Pharm Res· May 2024

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Optimal quantification of residence time distribution profiles from a quality assurance perspective.
Pooja Bhalode, Sonia M Razavi, Andrés Roman-Ospino, James Scicolone, Gerardo Callegari, Fernando J Muzzio

Int J Pharm· March 2023

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Characterization and propagation of RTD uncertainty for continuous powder blending processes.
Huayu Tian, Pooja Bhalode, Sonia M Razavi, Abdollah Koolivand, Fernando J Muzzio

Int J Pharm· November 2022

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NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination.
Sameer Talwar, Pallavi Pawar, Huiquan Wu, Koushik Sowrirajan, Suyang Wu, Fernando J Muzzio

AAPS J· September 2022

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Multi-layer Raman chemical mapping to investigate the effect of API particle size and blending shear rate on API domain sizes in pharmaceutical tablets.
Shashwat Gupta, Benoît Igne, Thamer Omar, Andrés D Román-Ospino, Douglas Hausner, Fernando Muzzio

Int J Pharm· August 2022

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Prediction of entire tablet formulations from pure powder components' spectra via a two-step non-linear optimization methodology.
Yukteshwar Baranwal, Andrés D Román-Ospino, Jingzhe Li, Sonia M Razavi, Fernando J Muzzio

Int J Pharm· March 2022

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Residence time distribution as a traceability method for lot changes in a pharmaceutical continuous manufacturing system.
Adriluz Sánchez-Paternina, Pedro Martínez-Cartagena, Jingzhe Li, James Scicolone, Ravendra Singh, Fernando J Muzzio

Int J Pharm· January 2022

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SEM/EDX and Raman chemical imaging of pharmaceutical tablets: A comparison of tablet surface preparation and analysis methods.
Shashwat Gupta, Thamer Omar, Fernando J Muzzio

Int J Pharm· January 2022

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Using residence time distribution in pharmaceutical solid dose manufacturing - A critical review.
Pooja Bhalode, Huayu Tian, Shashwat Gupta, Sonia M Razavi, Andres Roman-Ospino, Fernando J Muzzio

Int J Pharm· December 2021

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Dissolution Study on Grape Polyphenol Hard Gelatin Capsule Dietary Supplements.
Weiting Lyu, Thamer Omar, Harna Patel, David Rodriguez, Mario G Ferruzzi, Fernando J Muzzio

Front Nutr· November 2021

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Performance assessment of linear iterative optimization technology (IOT) for Raman chemical mapping of pharmaceutical tablets.
Shashwat Gupta, Andrés D Román-Ospino, Yukteshwar Baranwal, Douglas Hausner, Rohit Ramachandran, Fernando J Muzzio

J Pharm Biomed Anal· October 2021

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Integrating sensors for monitoring blend content in a pharmaceutical continuous manufacturing plant.
Savitha Panikar, Jingzhe Li, Varsha Rane, Sean Gillam, Gerardo Callegari, Fernando Muzzio

Int J Pharm· September 2021

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Binder-free twin-screw melt granulation: An effective approach to manufacture high-dose API formulations.
Ivana Cotabarren, Thamer A Omar, Fernando J Muzzio

Int J Pharm· September 2021

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Sampling optimization for blend monitoring of a low dose formulation in a tablet press feed frame using spatially resolved near-infrared spectroscopy.
Andrés D Román-Ospino, Yukteshwar Baranwal, Jingzhe Li, Jenny Vargas, Benoît Igne, Fernando J Muzzio

Int J Pharm· June 2021

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Prediction of tablet weight variability in continuous manufacturing.
Sonia M Razavi, James Scicolone, Ronald D Snee, Ashish Kumar, Johny Bertels, Fernando Muzzio

Int J Pharm· February 2020

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Method transfer of a near-infrared spectroscopic method for blend uniformity in a poorly flowing and hygroscopic blend.
Bárbara B Alvarado-Hernández, James V Scicolone, Carlos Ortega-Zuniga, Andrés D Román-Ospino, Yleana M Colón-Lugo, Fernando J Muzzio

J Pharm Biomed Anal· February 2020

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Characterization of NIR interfaces for the feeding and in-line monitoring of a continuous granulation process.
Andrés D Román-Ospino, Ashutosh Tamrakar, Benoît Igne, Elyse Towns Dimaso, Christian Airiau, Fernando J Muzzio

Int J Pharm· January 2020

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Mixing Cell: a Device to Mimic Extent of Lubrication and Shear in Continuous Tubular Blenders.
Sara Moghtadernejad, M Sebastian Escotet-Espinoza, Zhanjie Liu, Elisabeth Schäfer, Fernando Muzzio

AAPS PharmSciTech· July 2019

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Prediction of dissolution profiles by non-destructive NIR spectroscopy in bilayer tablets.
Yukteshwar Baranwal, Andrés D Román-Ospino, Golshid Keyvan, Jung Myung Ha, Eon Pyo Hong, Fernando J Muzzio

Int J Pharm· June 2019

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Assessment of blend uniformity in a continuous tablet manufacturing process.
Nobel O Sierra-Vega, Andrés Román-Ospino, James Scicolone, Fernando J Muzzio, Rodolfo J Romañach

Int J Pharm· April 2019

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A comprehensive analysis and optimization of continuous twin-screw granulation processes via sequential experimentation strategy.
Wei Meng, Kallakuri Suparna Rao, Ronald D Snee, Rohit Ramachandran, Fernando J Muzzio

Int J Pharm· February 2019

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