Publications by authors named "Fernando P Varotti"

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Novel 1,3-Diazepines as Nontoxic Corrosion Inhibitors.
Ana J F Souza, Priscila M Souza, Gabriel R Antunes, Maxwel E Bille, Odeydes J R P Carvalho, Fernando P Varotti

ACS Omega· November 2025

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Novel Heterocyclic Compounds Exhibit Potent Antileukemic Activity through Selective Induction of Apoptosis and HDAC8 Interaction in AML Cells.
Túlio R Freitas, Fernanda de F S de Oliveira, Caique Lopes Duarte, Larissa R S P Baliza, Edward K S Gonçalves, Fernando de P Varotti

Anticancer Agents Med Chem· June 2025

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Trihydroxyflavanone isolated from Dipteryx lacunifera Ducke (Fabaceae) as a potential antimalarial drug: An in silico and in vitro approach.
Fernanda A Oliveira, Cleberson Lira, Caíque L Duarte, Karla S Guedes, Amanda Luisa DA Fonseca, Fernando P Varotti

An Acad Bras Cienc· April 2025

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Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals.
Larissa R S P Baliza, Túlio R Freitas, Edward K S Gonçalves, Gabriel R Antunes, Ana J F Souza, Fernando P Varotti

Chem Biol Drug Des· July 2024

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Toxicological effects of hydroxychloroquine sulfate and chloroquine diphosphate substances on the early-life stages of fish in the COVID-19 pandemic context.
Isabella Ferreira Silva, Keiza Priscila Enes, Gustavo Machado Rocha, Fernando Pilla Varotti, Leandro Augusto Barbosa

J Environ Sci Health A Tox Hazard Subst Environ Eng· August 2023

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Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives.
Fernanda A Oliveira, Ana Claudia S Pinto, Caique L Duarte, Alex G Taranto, Eder Lorenzato Junior, Fernando P Varotti

BMC Chem· July 2022

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21-Benzylidene digoxin decreases proliferation by inhibiting the EGFR/ERK signaling pathway and induces apoptosis in HeLa cells.
Marco Túlio C Pessôa, Jéssica M M Valadares, Sayonarah C Rocha, Simone C Silva, Jeff P McDermott, Fernando P Varotti

Steroids· March 2020

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New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.
Israel José Pereira Garcia, Gisele Capanema de Oliveira, Jéssica Martins de Moura Valadares, Felipe Finger Banfi, Silmara Nunes Andrade, Fernando P Varotti

Steroids· December 2019

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Novel Symmetrical 1,4-Disubstituted-bis-1,2,3-Triazoles: Synthesis by Double CuAAC and Cytotoxicity Evaluation.
Wallace J Reis, Paulo O L Moreira, Rosemeire B Alves, Heloísa H M Oliveira, Luciana M Silva, Fernando P Varotti

Curr Top Med Chem· January 2019

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Larvicidal activity of vegetable oils and esterified compounds against Culex quinquefasciatus (Diptera: Culicidae).
José A Ribeiro-Neto, Maria Eduarda A Pinto, Vanessa V Ferreira, Jacqueline D Tibúrcio, Fernando P Varotti

Ecotoxicol Environ Saf· September 2017

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Revealing the Binding Process of New 3-Alkylpyridine Marine Alkaloid Analogue Antimalarials and the Heme Group: An Experimental and Theoretical Investigation.
Renato M Ribeiro-Viana, Anna P Butera, Eliziane S Santos, César A Tischer, Rosemeire B Alves, Fernando P Varotti

J Chem Inf Model· March 2016

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Hypervalent organotellurium compounds as inhibitors of P. falciparum calcium-dependent cysteine proteases.
Sarah El Chamy Maluf, Pollyana M S Melo, Fernando P Varotti, Marcos L Gazarini, Rodrigo L O R Cunha

Parasitol Int· February 2016

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γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect.
Silmara L G Alves, Natasha Paixão, Letícia G R Ferreira, Felipe R S Santos, Luiza D R Neves, Fernando P Varotti

Bioorg Med Chem· August 2015

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21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions.
Sayonarah C Rocha, Marco T C Pessoa, Luiza D R Neves, Silmara L G Alves, Luciana M Silva, Fernando P Varotti

PLoS One· June 2015

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Synthesis, cytotoxicity and antiplasmodial activity of novel ent-kaurane derivatives.
Ronan Batista, Pablo A García, María Angeles Castro, José M Miguel Del Corral, Nivaldo L Speziali, Fernando de P Varotti

Eur J Med Chem· April 2013

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Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells.
Graziele D da Silva, Marina G da Silva, Estrela M P V E Souza, Andersson Barison, Sarah C Simões, Fernando P Varotti

Molecules· August 2012

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Plant-derived antimalarial agents: new leads and efficient phythomedicines. Part I. Alkaloids.
Alaíde B Oliveira, Maria Fâni Dolabela, Fernão C Braga, Rose L R P Jácome, Fernando P Varotti

An Acad Bras Cienc· December 2009

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Synthesis, antimalarial evaluation and molecular modeling studies of hydroxyethylpiperazines, potential aspartyl protease inhibitors, part 2.
Wilson Cunico, Claudia R B Gomes, Victor Facchinetti, Marcele Moreth, Carmen Penido, Fernando P Varotti

Eur J Med Chem· September 2009

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Synthesis and antimalarial activity of hydroxyethylpiperazine derivatives.
Wilson Cunico, Claudia R B Gomes, Marcele Moreth, Diogo P Manhanini, Isabela H Figueiredo, Fernando P Varotti

Eur J Med Chem· March 2009

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Validation of a Plasmodium falciparum parasite transformed with green fluorescent protein for antimalarial drug screening.
Bruno A M Sanchez, Fernando P Varotti, Flávia G Rodrigues, Luzia H Carvalho

J Microbiol Methods· June 2007

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Plasmodium falciparum malaria parasites display a THG-sensitive Ca2+ pool.
Fernando P Varotti, Flávio H Beraldo, Marcos L Gazarini, Célia R S Garcia

Cell Calcium· February 2003

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