Publications by authors named "Fikret Turkan"

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3-Substituted Triazolone-Benzoate Hybrids: Synthesis, Enzyme Inhibition, Anticancer Activity and ADMET Evaluation by Molecular Docking and Dynamics Studies.
Murat Beytur, Elif Tarmaşır, Ercan Oguz, Alpaslan Bayrakdar, İlhan Sabancılar

Drug Dev Res· February 2026

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Pyrimidine Based Inhibitors Targeting Glutathione S-Transferase in Phase II Detoxification: Antioxidant, ADMET, Docking, and Molecular Dynamics Evaluation.
Fikret Türkan, Adnan Cetin, Meryem Ayan Ustun

J Biochem Mol Toxicol· December 2025

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Design, Synthesis, and Characterization of Novel Substituted 1,2,4-Triazines: Cytotoxic Activity on HepG2 and HT-29 Cell Lines, Enzyme Inhibition, and Molecular Docking Studies.
Adnan Cetin, Ercan Oguz, Ewa Wolińska, Przemysław Rozbicki, Danuta Branowska

J Biochem Mol Toxicol· November 2025

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Dual Inhibition of AChE and GST by 1,2,4-Triazine-3-Amine: Integrated Biochemical, Computational, and Hepatotoxicity Insights.
Ercan Oguz, Gizem Sertkaya Tulek, Elsevar Asadove, Adnan Cetin, Fikret Türkan

Biotechnol Appl Biochem· November 2025

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New methyl/benzyl-1,2,4-triazole-3-one Derivatives: Synthesis, Characterization (IR, NMR), Antidiabetic, Anti-Alzheimer, and Molecular Docking Study.
Fatih Çelik, Yasemin Ünver, Halil İbrahim Güler, Ercan Oğuz, Fikret Türkan

J Biochem Mol Toxicol· September 2025

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The Cytotoxic Effect on HepG2 Cell Line and In Vitro, In Silico Evaluation of 1,2,4-Triazine Compounds as Inhibitors of Acetylcholinesterase and Glutathione S-Transferase.
Fikret Türkan, Adnan Cetin, Semanur Kalkan, Ercan Oguz

J Biochem Mol Toxicol· August 2025

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Synthesis and characterization of novel bis(thiosemicarbazone) complexes and investigation of their acetylcholinesterase and glutathione S-transferase activities with in silico and in vitro studies.
Melike Donmez, Memet Sekerci, Ragip Adiguzel, Ercan Oğuz, Fikret Türkan

Mol Divers· April 2025

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Synthesis and examination of 1,2,4-triazine-sulfonamide hybrids as potential inhibitory drugs: Inhibition effects on AChE and GST enzymes in silico and in vitro conditions.
Przemysław Rozbicki, Ercan Oğuz, Ewa Wolińska, Fikret Türkan, Adnan Cetin

Arch Pharm (Weinheim)· September 2024

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Effects of fluoride on oxidative DNA damage, nitric oxide level, lipid peroxidation and cholinesterase enzyme activity in a rotenone-induced experimental Parkinson's model.
Yilmaz Kocak, Gokhan Oto, Zubeyir Huyut, Hamit Hakan Alp, Fikret Turkan

Neurol Res· November 2023

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Corrigendum to "In vivo biochemical evaluations of some β-lactam group antibiotics on glutathione reductase and glutathione S-transferase enzyme activities" [Life Sci., volume 231 (2019) 116572].
Fikret Türkan, Zübeyir Huyut, Mehmet Tahir Huyut, Mehmet Harbi Calimli

Life Sci· November 2023

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Synthesis and acetylcholinesterase enzyme inhibitory effects of some novel 4,5-Dihydro-1-1,2,4-triazol-5-one derivatives; an and study.
Hilal Medetalibeyoğlu, Fikret Türkan, Sevda Manap, Ercan Bursal, Murat Beytur

J Biomol Struct Dyn· July 2023

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Piperazine derivatives with potent drug moiety as efficient acetylcholinesterase, butyrylcholinesterase, and glutathione S-transferase inhibitors.
Mahmut Onur Karaytuğ, Neslihan Balcı, Fikret Türkan, Mahmut Gürbüz, Mehmet Emin Demirkol

J Biochem Mol Toxicol· February 2023

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and enzyme inhibition effects of some metal ions and compounds on glutathione S-transferase enzyme purified from L.
Neslihan Balcı, Halis Şakiroğlu, Fikret Türkan, Ercan Bursal

J Biomol Struct Dyn· December 2022

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New chalcone derivative, ethyl 2-(4-(3-(benzo[]thiophen-2-yl)acryloyl)phenoxy)acetate: synthesis, characterization, DFT study, enzyme inhibition activities and docking study.
Fatih Çelik, Nevin Süleymanoğlu, Reşat Ustabaş, Fikret Türkan, Halil İbrahim Güler

J Biomol Struct Dyn· December 2022

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Some metal chelates with Schiff base ligand: synthesis, structure elucidation, thermal behavior, XRD evaluation, antioxidant activity, enzyme inhibition, and molecular docking studies.
Nevin Turan, Kenan Buldurun, Fikret Türkan, Abdulmelik Aras, Naki Çolak

Mol Divers· October 2022

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Metal contained Phthalocyanines with 3,4-Dimethoxyphenethoxy substituents: their anticancer, antibacterial activities and their inhibitory effects on some metabolic enzymes with molecular docking studies.
Parham Taslimi, Fikret Türkan, Derya Güngördü Solğun, Abdülmelik Aras, Yavuz Erden

J Biomol Struct Dyn· April 2022

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Synthesis, Spectroscopic Analysis, and in Vitro/in Silico Biological Studies of Novel Piperidine Derivatives Heterocyclic Schiff-Mannich Base Compounds.
Songül Boy, Abdülmelik Aras, Fikret Türkan, Onur Akyıldırım, Murat Beytur

Chem Biodivers· December 2021

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The effects of Daucus carota extract against PC3, PNT1a prostate cells, acetylcholinesterase, glutathione S-transferase, and α-glycosidase; an in vitro-in silico study.
Mehmet Nuri Atalar, Abdülmelik Aras, Fikret Türkan, Neslisah Barlak, Ümit Yildiko

J Food Biochem· December 2021

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Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes.
Kenan Buldurun, Nevin Turan, Ercan Bursal, Abdulmelik Aras, Asim Mantarcı

J Biomol Struct Dyn· October 2021

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Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods.
Ercan Bursal, Mustafa Abdullah Yılmaz, Ebubekir Izol, Fikret Türkan, Mehmet Nuri Atalar

Biophys Chem· October 2021

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Benzenesulfonamide derivatives as potent acetylcholinesterase, α-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies.
Parham Taslimi, Mesut Işık, Fikret Türkan, Mustafa Durgun, Cüneyt Türkeş

J Biomol Struct Dyn· September 2021

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Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies.
Ercan Bursal, Fikret Turkan, Kenan Buldurun, Nevin Turan, Abdulmelik Aras

Biometals· April 2021

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Synthesis, design, and assessment of novel morpholine-derived Mannich bases as multifunctional agents for the potential enzyme inhibitory properties including docking study.
Songül Boy, Fikret Türkan, Murat Beytur, Abdülmelik Aras, Onur Akyıldırım

Bioorg Chem· February 2021

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Synthesis of novel 1,2,3 triazole derivatives and assessment of their potential cholinesterases, glutathione S-transferase enzymes inhibitory properties: An in vitro and in silico study.
Fatih Çelik, Fikret Türkan, Abdülmelik Aras, Mehmet Nuri Atalar, Halide Sedef Karaman

Bioorg Chem· February 2021

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Comparison of the protective effects of curcumin and caffeic acid phenethyl ester against doxorubicin-induced testicular toxicity.
Zübeyir Huyut, Hamit Hakan Alp, Turan Yaman, Ömer Faruk Keleş, Zabit Yener

Andrologia· December 2020

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