Publications by authors named "Filomena Fezza"

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FAAH Modulators from Natural Sources: A Collection of New Potential Drugs.
Catalin Nicoara, Filomena Fezza, Mauro Maccarrone

Cells· April 2025

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RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models.
Uwe Grether, Richard H Foxton, Sabine Gruener, Claudia Korn, Atsushi Kimbara, Filomena Fezza

Front Pharmacol· July 2024

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Computational and Experimental Drug Repurposing of FDA-Approved Compounds Targeting the Cannabinoid Receptor CB1.
Emanuele Criscuolo, Maria Laura De Sciscio, Angela De Cristofaro, Catalin Nicoara, Mauro Maccarrone, Filomena Fezza

Pharmaceuticals (Basel)· December 2023

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Radiometric Assay of NAPE-PLD Activity.
Filomena Fezza, Nicolina Mastrangelo, Mauro Maccarrone

Methods Mol Biol· April 2023

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Chemical Proteomics Reveals Off-Targets of the Anandamide Reuptake Inhibitor WOBE437.
Berend Gagestein, Anna F Stevens, Domenico Fazio, Bogdan I Florea, Tom van der Wel, Filomena Fezza

ACS Chem Biol· May 2022

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Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents.
Alessandro Grillo, Filomena Fezza, Giulia Chemi, Roberto Colangeli, Simone Brogi

ACS Chem Neurosci· May 2021

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In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors.
Emanuele Criscuolo, Maria Laura De Sciscio, Filomena Fezza, Mauro Maccarrone

Molecules· December 2020

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Bisphenol A Deranges the Endocannabinoid System of Primary Sertoli Cells with an Impact on Inhibin B Production.
Gianna Rossi, Beatrice Dufrusine, Anna Rita Lizzi, Carla Luzi, Alessandra Piccoli, Filomena Fezza

Int J Mol Sci· November 2020

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Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold?
Domenico Fazio, Emanuele Criscuolo, Alessandra Piccoli, Barbara Barboni, Filomena Fezza

Expert Opin Drug Discov· July 2020

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Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response.
Luana Greco, Valentina Russo, Cinzia Rapino, Clara Di Germanio, Filomena Fezza

Cells· April 2020

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Author Correction: The endocannabinoid hydrolase FAAH is an allosteric enzyme.
Enrico Dainese, Sergio Oddi, Monica Simonetti, Annalaura Sabatucci, Clotilde B Angelucci, Filomena Fezza

Sci Rep· March 2020

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The endocannabinoid hydrolase FAAH is an allosteric enzyme.
Enrico Dainese, Sergio Oddi, Monica Simonetti, Annalaura Sabatucci, Clotilde B Angelucci, Filomena Fezza

Sci Rep· February 2020

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Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems.
Alessandro Grillo, Giulia Chemi, Simone Brogi, Margherita Brindisi, Nicola Relitti, Filomena Fezza

Eur J Med Chem· December 2019

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Assay of NAPE-PLD Activity.
Filomena Fezza, Nicolina Mastrangelo, Mauro Maccarrone

Methods Mol Biol· December 2017

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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.
Annelot C M van Esbroeck, Antonius P A Janssen, Armand B Cognetta, Daisuke Ogasawara, Guy Shpak, Filomena Fezza

Science· June 2017

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Palmitoylation of cysteine 415 of CB receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1.
Sergio Oddi, Tomasz Maciej Stepniewski, Antonio Totaro, Jana Selent, Lucia Scipioni, Filomena Fezza

Biochim Biophys Acta Mol Cell Biol Lipids· May 2017

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Cannabinoid CB receptor ligand profiling reveals biased signalling and off-target activity.
Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W Grim, Filomena Fezza

Nat Commun· January 2017

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Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS.
Mesut Bilgin, Petra Born, Filomena Fezza, Michael Heimes, Nicolina Mastrangelo

Sci Rep· June 2016

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Plant-Derived and Endogenous Cannabinoids in Epilepsy.
Alberto Verrotti, Miriam Castagnino, Mauro Maccarrone, Filomena Fezza

Clin Drug Investig· May 2016

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The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.
Partha Mukhopadhyay, Marc Baggelaar, Katalin Erdelyi, Zongxian Cao, Resat Cinar, Filomena Fezza

Br J Pharmacol· February 2016

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Endocannabinoids, related compounds and their metabolic routes.
Filomena Fezza, Monica Bari, Rita Florio, Emanuela Talamonti, Monica Feole

Molecules· October 2014

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Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting.
Filomena Fezza, Maria C Marrone, Riccardo Avvisati, Monia Di Tommaso, Mirko Lanuti

Mol Cell Neurosci· September 2014

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Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor.
Valerio Chiurchiù, Mirko Lanuti, Giuseppina Catanzaro, Filomena Fezza, Cinzia Rapino

Atherosclerosis· March 2014

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Activation of type-2 cannabinoid receptor inhibits neuroprotective and antiinflammatory actions of glucocorticoid receptor α: when one is better than two.
Elisa Bisicchia, Valerio Chiurchiù, Maria Teresa Viscomi, Laura Latini, Filomena Fezza

Cell Mol Life Sci· June 2013

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Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties.
Stefania Butini, Sandra Gemma, Margherita Brindisi, Samuele Maramai, Patrizia Minetti, Filomena Fezza

Bioorg Med Chem Lett· January 2013

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