Publications by authors named "Fiona A Sharp"

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Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens.
Michael R Schlabach, Sharon Lin, Zachary R Collester, Christopher Wrocklage, Sol Shenker, Fiona A Sharp

J Clin Invest· December 2023

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Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles.
Natalia Muñoz-Wolf, Ross W Ward, Claire H Hearnden, Fiona A Sharp, Joan Geoghegan

Cell Rep Med· January 2023

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The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses.
Ewa Oleszycka, Sean McCluskey, Fiona A Sharp, Natalia Muñoz-Wolf, Emily Hams

Eur J Immunol· April 2018

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Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen.
Sandeep S Saluja, Douglas J Hanlon, Fiona A Sharp, Enping Hong, David Khalil

Int J Nanomedicine· July 2015

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A carbon nanotube-polymer composite for T-cell therapy.
Tarek R Fadel, Fiona A Sharp, Nalini Vudattu, Ragy Ragheb, Justin Garyu

Nat Nanotechnol· August 2014

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The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses.
Andres Mori, Ewa Oleszycka, Fiona A Sharp, Michelle Coleman, Yuki Ozasa

Eur J Immunol· October 2012

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Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines.
Stacey L Demento, Alyssa L Siefert, Arunima Bandyopadhyay, Fiona A Sharp, Tarek M Fahmy

Trends Biotechnol· June 2011

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Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
James Harris, Michelle Hartman, Caitrionna Roche, Shijuan G Zeng, Amy O'Shea, Fiona A Sharp

J Biol Chem· March 2011

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Seth L Masters, Aisling Dunne, Shoba L Subramanian, Rebecca L Hull, Gillian M Tannahill, Fiona A Sharp

Nat Immunol· October 2010

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The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants.
James Harris, Fiona A Sharp, Ed C Lavelle

Eur J Immunol· March 2010

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Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.
Fiona A Sharp, Darren Ruane, Benjamin Claass, Emma Creagh, James Harris

Proc Natl Acad Sci U S A· January 2009

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