Publications by authors named "Fitzgerald Lao"

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Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx.
Yukiya Sako, Fumi Sato-Kaneko, Nikunj M Shukla, Shiyin Yao, Masiel M Belsuzarri, Fitzgerald S Lao

ACS Chem Biol· April 2023

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A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination.
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S Lao, Yukiya Sako, Jasmine Jin

Vaccines (Basel)· October 2022

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A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity.
Nikunj M Shukla, Fumi Sato-Kaneko, Shiyin Yao, Minya Pu, Michael Chan, Fitzgerald S Lao

Front Pharmacol· April 2022

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Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity.
Tetsuya Saito, Nikunj M Shukla, Fumi Sato-Kaneko, Yukiya Sako, Tadashi Hosoya, Fitzgerald S Lao

ACS Chem Biol· January 2022

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Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Tetsuya Saito, Yukiya Sako, Fumi Sato-Kaneko, Tadashi Hosoya, Shiyin Yao, Fitzgerald S Lao

Front Immunol· December 2021

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Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation.
Nikunj M Shukla, Michael Chan, Fitzgerald S Lao, Paul J Chu, Masiel Belsuzarri

Bioorg Med Chem· August 2021

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Mitochondria-dependent synthetic small-molecule vaccine adjuvants for influenza virus infection.
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S Lao, Jason Nan, Jonathan Shpigelman

Proc Natl Acad Sci U S A· June 2021

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A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity.
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S Lao, Jonathan Shpigelman, Karen Messer

Front Immunol· April 2021

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Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release.
Jonathan Shpigelman, Fitzgerald S Lao, Shiyin Yao, Chenyang Li, Tetsuya Saito

Front Pharmacol· April 2021

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Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Tadashi Hosoya, Nikunj M Shukla, Yuya Fujita, Shiyin Yao, Fitzgerald S Lao

Front Pharmacol· December 2020

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Structure-Activity Relationship Studies To Identify Affinity Probes in Bis-aryl Sulfonamides That Prolong Immune Stimuli.
Michael Chan, Fitzgerald S Lao, Paul J Chu, Jonathan Shpigelman, Shiyin Yao

J Med Chem· November 2019

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Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy.
Fumi Sato-Kaneko, Xiaodong Wang, Shiyin Yao, Tadashi Hosoya, Fitzgerald S Lao

Biomed Res Int· February 2019

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Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants.
Nikunj M Shukla, Kei-Ichiro Arimoto, Shiyin Yao, Jun-Bao Fan, Yue Zhang, Fitzgerald S Lao

SLAS Discov· October 2018

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Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist.
Tadashi Hosoya, Fumi Sato-Kaneko, Alast Ahmadi, Shiyin Yao, Fitzgerald Lao

Proc Natl Acad Sci U S A· July 2018

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Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1.
Michael Y Choi, George F Widhopf, Christina C N Wu, Bing Cui, Fitzgerald Lao

Clin Lymphoma Myeloma Leuk· June 2015

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Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand.
Christina C N Wu, Brian Crain, Shiyin Yao, Mojgan Sabet, Fitzgerald S Lao

J Innate Immun· May 2015

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Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44.
Suping Zhang, Christina C N Wu, Jessie-F Fecteau, Bing Cui, Liguang Chen, Fitzgerald Lao

Proc Natl Acad Sci U S A· April 2013

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Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system.
Tomoko Hayashi, Shiyin Yao, Brian Crain, Michael Chan, Rommel I Tawatao, Fitzgerald Lao

PLoS One· February 2013

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Mast cell-mediated inhibition of abdominal neutrophil inflammation by a PEGylated TLR7 ligand.
Tomoko Hayashi, Shiyin Yao, Brian Crain, Michael Chan, Howard B Cottam, Fitzgerald Lao

Mediators Inflamm· September 2012

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Synthesis and characterization of PEGylated toll like receptor 7 ligands.
Michael Chan, Tomoko Hayashi, Richard D Mathewson, Shiyin Yao, Christine Gray, Fitzgerald S Lao

Bioconjug Chem· March 2011

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