Publications by authors named "Flavio Maina"

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Low-GPX4 drives a sustained drug-tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation.
Nazia Chaudhary, Dibita Mandal, Bhagya Shree Choudhary, Sushmita Patra, Darshan Jain, Flavio Maina

Redox Biol· November 2025

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Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response.
Carlos González-Corralejo, Juan García-Sáez, María Figueroa-Fuentes, Annalisa Addante, Cesáreo Roncero, Flavio Maina

FEBS J· November 2025

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Establishment of a mouse hepatocellular carcinoma tumoroid panel recapitulating inter- and intra- heterogeneity for disease modelling and combinatorial drug discovery.
Margherita Grattarola, Nicolas Pons, Floriane Cannet, Müge Kaya, Abdessamad El Kaoutari, Flavio Maina

Cell Commun Signal· October 2025

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The HDAC inhibitor romidepsin renders liver cancer vulnerable to RTK targeting and immunologically active.
Celia Sequera, Margherita Grattarola, Floriane Cannet, Aurélie Dobric, Paula Michea Veloso, Flavio Maina

Nat Commun· August 2025

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Tracing specificity of immune landscape remodeling associated with distinct anticancer treatments.
Floriane Cannet, Célia Sequera, Paula Michea Veloso, Abdessamad El Kaoutari, Melissa Methia, Flavio Maina

iScience· March 2025

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Uncovering a Novel Functional Interaction Between Adult Hepatic Progenitor Cells, Inflammation and EGFR Signaling During Bile Acids-Induced Injury.
Juan García-Sáez, María Figueroa-Fuentes, Carlos González-Corralejo, Cesáreo Roncero, Nerea Lazcanoiturburu, Flavio Maina

Int J Biol Sci· May 2024

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Epithelial disruption drives mesendoderm differentiation in human pluripotent stem cells by enabling TGF-β protein sensing.
Thomas Legier, Diane Rattier, Jack Llewellyn, Thomas Vannier, Benoit Sorre, Flavio Maina

Nat Commun· January 2023

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MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities.
Celia Sequera, Margherita Grattarola, Agnes Holczbauer, Rosanna Dono, Stefania Pizzimenti, Flavio Maina

Cell Death Dis· November 2022

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BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators.
Olivier Castellanet, Fahmida Ahmad, Yaron Vinik, Gordon B Mills, Bianca Habermann, Flavio Maina

Theranostics· February 2022

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Enhanced Wild-Type MET Receptor Levels in Mouse Hepatocytes Attenuates Insulin-Mediated Signaling.
Patricia Rada, Fabienne Lamballe, Elena Carceller-López, Ana B Hitos, Celia Sequera, Flavio Maina

Cells· February 2022

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Two is better than one: combinatorial receptor targeting enhances hepatocellular carcinoma (HCC) therapeutic response.
Celia Sequera, Flavio Maina

Hepatobiliary Surg Nutr· February 2022

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The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC.
Lohit Khera, Yaron Vinik, Flavio Maina, Sima Lev

Life Sci Alliance· June 2021

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Enhanced differentiation of human induced pluripotent stem cells toward the midbrain dopaminergic neuron lineage through GLYPICAN-4 downregulation.
Serena Corti, Remi Bonjean, Thomas Legier, Diane Rattier, Christophe Melon, Flavio Maina

Stem Cells Transl Med· May 2021

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ADAMTSL5 is an epigenetically activated gene underlying tumorigenesis and drug resistance in hepatocellular carcinoma.
Maria Arechederra, Sehrish K Bazai, Ahmed Abdouni, Celia Sequera, Timothy J Mead, Flavio Maina

J Hepatol· April 2021

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Turning up our understanding of liver cancer by a notch.
Amaia Lujambio, Flavio Maina

J Hepatol· March 2021

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Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance.
Fabienne Lamballe, Fahmida Ahmad, Yaron Vinik, Olivier Castellanet, Fabrice Daian, Flavio Maina

Adv Sci (Weinh)· February 2021

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C3G Is Upregulated in Hepatocarcinoma, Contributing to Tumor Growth and Progression and to HGF/MET Pathway Activation.
Celia Sequera, Paloma Bragado, Sara Manzano, Maria Arechederra, Sylvie Richelme, Flavio Maina

Cancers (Basel)· August 2020

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Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis.
Nandini Verma, Yaron Vinik, Ashish Saroha, Nishanth Ulhas Nair, Eytan Ruppin, Flavio Maina

Sci Adv· August 2020

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Large-Scale Virtual Screening Against the MET Kinase Domain Identifies a New Putative Inhibitor Type.
Emmanuel Bresso, Alessandro Furlan, Philippe Noel, Vincent Leroux, Flavio Maina

Molecules· February 2020

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Tracking Dynamics of Spontaneous Tumors in Mice Using Photon-Counting Computed Tomography.
Franca Cassol, Loriane Portal, Sylvie Richelme, Mathieu Dupont, Yannick Boursier, Flavio Maina

iScience· November 2019

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Liver Cancer Gene Discovery Using Gene Targeting, Sleeping Beauty, and CRISPR/Cas9.
Julia E Kieckhaefer, Flavio Maina, Rebecca G Wells, Kirk J Wangensteen

Semin Liver Dis· May 2019

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Evaluating the landscape of gene cooperativity with receptor tyrosine kinases in liver tumorigenesis using transposon-mediated mutagenesis.
Yannan Fan, Sehrish K Bazai, Fabrice Daian, Maria Arechederra, Sylvie Richelme, Flavio Maina

J Hepatol· March 2019

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Publisher Correction: Hypermethylation of gene body CpG islands predicts high dosage of functional oncogenes in liver cancer.
Maria Arechederra, Fabrice Daian, Annie Yim, Sehrish K Bazai, Sylvie Richelme, Flavio Maina

Nat Commun· September 2018

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Hypermethylation of gene body CpG islands predicts high dosage of functional oncogenes in liver cancer.
Maria Arechederra, Fabrice Daian, Annie Yim, Sehrish K Bazai, Sylvie Richelme, Flavio Maina

Nat Commun· August 2018

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Genomic Status of Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
Jacqueline D Peacock, Matthew G Pridgeon, Elizabeth A Tovar, Curt J Essenburg, Megan Bowman, Flavio Maina

Cancer Res· July 2018

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