Publications by authors named "Flora Mela"

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Effects of dopamine uptake inhibitor MRZ-9547 in animal models of Parkinson's disease.
Andrzej Dekundy, Flora Mela, Martine Hofmann, Wojciech Danysz

J Neural Transm (Vienna)· June 2015

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GluN2A and GluN2B NMDA receptor subunits differentially modulate striatal output pathways and contribute to levodopa-induced abnormal involuntary movements in dyskinetic rats.
Omar S Mabrouk, Flora Mela, Mariangela Calcagno, Mirco Budri, Riccardo Viaro

ACS Chem Neurosci· May 2013

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In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels.
Flora Mela, Matteo Marti, Simone Bido, M Angela Cenci, Michele Morari

Neurobiol Dis· January 2012

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Pharmacological characterization of MRZ-8676, a novel negative allosteric modulator of subtype 5 metabotropic glutamate receptors (mGluR5): focus on L: -DOPA-induced dyskinesia.
Andrzej Dekundy, Andreas Gravius, Mirko Hechenberger, Małgorzata Pietraszek, Jens Nagel, Flora Mela

J Neural Transm (Vienna)· December 2011

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The selective D(3) receptor antagonist, S33084, improves parkinsonian-like motor dysfunction but does not affect L-DOPA-induced dyskinesia in 6-hydroxydopamine hemi-lesioned rats.
Flora Mela, Mark J Millan, Mauricette Brocco, Michele Morari

Neuropharmacology· February 2010

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Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling.
Daniella Rylander, Alessandra Recchia, Flora Mela, Andrzej Dekundy, Wojciech Danysz

J Pharmacol Exp Ther· July 2009

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Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease.
Flora Mela, Matteo Marti, Andrzej Dekundy, Wojciech Danysz, Michele Morari

J Neurochem· April 2007

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Group-II metabotropic glutamate receptors negatively modulate NMDA transmission at striatal cholinergic terminals: role of P/Q-type high voltage activated Ca++ channels and endogenous dopamine.
Flora Mela, Matteo Marti, Chiara Fiorentini, Cristina Missale, Michele Morari

Mol Cell Neurosci· February 2006

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Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.
Matteo Marti, Flora Mela, Martina Fantin, Silvia Zucchini, Jeffrey M Brown

J Neurosci· October 2005

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[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.
Giacomo Carrà, Anna Rizzi, Remo Guerrini, Timothy A Barnes, John McDonald, Flora Mela

J Pharmacol Exp Ther· March 2005

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Blockade of nociceptin/orphanin FQ transmission in rat substantia nigra reverses haloperidol-induced akinesia and normalizes nigral glutamate release.
Matteo Marti, Flora Mela, Remo Guerrini, Girolamo Calò, Clementina Bianchi

J Neurochem· December 2004

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Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior.
Matteo Marti, Flora Mela, Carlo Veronesi, Remo Guerrini, Severo Salvadori

J Neurosci· July 2004

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Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex.
Flora Mela, Matteo Marti, Linda Ulazzi, Elvis Vaccari, Silvia Zucchini

Eur J Neurosci· March 2004

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Plasticity of glutamatergic control of striatal acetylcholine release in experimental parkinsonism: opposite changes at group-II metabotropic and NMDA receptors.
Matteo Marti, Francesca Paganini, Sara Stocchi, Flora Mela, Lorenzo Beani

J Neurochem· February 2003

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Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex.
Matteo Marti, Sara Stocchi, Francesca Paganini, Flora Mela, Carmela De Risi

Br J Pharmacol· January 2003

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Striatal dopamine-NMDA receptor interactions in the modulation of glutamate release in the substantia nigra pars reticulata in vivo: opposite role for D1 and D2 receptors.
Matteo Marti, Flora Mela, Clementina Bianchi, Lorenzo Beani, Michele Morari

J Neurochem· November 2002

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