Publications by authors named "Flora Vitale"

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RETRACTED: Gravina et al. The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models. 2019, , 359.
Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale

Cancers (Basel)· December 2025

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RETRACTED: Gravina et al. The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine Models. 2019, , 1604.
Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale

Cancers (Basel)· December 2025

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The Botanical Drug PBI-05204, a Supercritical CO Extract of Nerium Oleander, Is Synergistic With Radiotherapy in Models of Human Glioblastoma.
Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale

Front Pharmacol· March 2022

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Pedunculopontine tegmental Nucleus-evoked prepulse inhibition of the blink reflex in Parkinson's disease.
Angelo Insola, Paolo Mazzone, Giacomo Della Marca, Annamaria Capozzo, Flora Vitale

Clin Neurophysiol· October 2021

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The Botanical Drug PBI-05204, a Supercritical CO Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties.
Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale

Front Pharmacol· September 2020

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Crocetin Extracted from Saffron Shows Antitumor Effects in Models of Human Glioblastoma.
Alessandro Colapietro, Andrea Mancini, Flora Vitale, Stefano Martellucci, Adriano Angelucci

Int J Mol Sci· January 2020

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RETRACTED: The Brain Penetrating and Dual TORC1/TORC2 Inhibitor, RES529, Elicits Anti-Glioma Activity and Enhances the Therapeutic Effects of Anti-Angiogenetic Compounds in Preclinical Murine Models.
Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale

Cancers (Basel)· October 2019

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RETRACTION: The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models.
Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Simona Delle Monache, Roberta Sferra, Flora Vitale

Cancers (Basel)· March 2019

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The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.
Claudio Festuccia, Andrea Mancini, Alessandro Colapietro, Giovanni Luca Gravina, Flora Vitale

J Hematol Oncol· February 2018

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The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models.
Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Flora Vitale, Antonella Vetuschi

Tumour Biol· June 2017

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Fluorescent light induces neurodegeneration in the rodent nigrostriatal system but near infrared LED light does not.
Stefania Romeo, Flora Vitale, Cristina Viaggi, Stefano di Marco, Gabriella Aloisi

Brain Res· May 2017

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Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models.
Giovanni Luca Gravina, Andrea Mancini, Claudia Mattei, Flora Vitale, Francesco Marampon

Oncotarget· May 2017

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The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma.
Giovanni Luca Gravina, Andrea Mancini, Francesco Marampon, Alessandro Colapietro, Simona Delle Monache, Flora Vitale

J Hematol Oncol· January 2017

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Our first decade of experience in deep brain stimulation of the brainstem: elucidating the mechanism of action of stimulation of the ventrolateral pontine tegmentum.
Paolo Mazzone, Osvaldo Vilela Filho, Fabio Viselli, Angelo Insola, Stefano Sposato, Flora Vitale

J Neural Transm (Vienna)· July 2016

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Suppression of SRC Signaling Is Effective in Reducing Synergy between Glioblastoma and Stromal Cells.
Alessia Calgani, Giulia Vignaroli, Claudio Zamperini, Federica Coniglio, Claudio Festuccia, Flora Vitale

Mol Cancer Ther· July 2016

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Cholinergic input from the pedunculopontine nucleus to the cerebellum: implications for deep brain stimulation in Parkinson's disease.
Eugenio Scarnati, Flora Vitale, Annamaria Capozzo, Paolo Mazzone

Neural Regen Res· May 2016

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Metabolic, synaptic and behavioral impact of 5-week chronic deep brain stimulation in hemiparkinsonian rats.
Carine Chassain, Christophe Melon, Pascal Salin, Flora Vitale, Sébastien Couraud

J Neurochem· March 2016

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Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models.
Giovanni Luca Gravina, Andrea Mancini, Luca Scarsella, Alessandro Colapietro, Ana Jitariuc, Flora Vitale

Tumour Biol· January 2016

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Erratum to: KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin in prostate cancer models.
Giovanni Luca Gravina, Andrea Mancini, Patrizia Sanita, Flora Vitale, Francesco Marampon

BMC Cancer· January 2016

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KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.
Giovanni Luca Gravina, Andrea Mancini, Patrizia Sanita, Flora Vitale, Francesco Marampon

BMC Cancer· December 2015

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Continuous stimulation of the pedunculopontine tegmental nucleus at 40 Hz affects preparative and executive control in a delayed sensorimotor task and reduces rotational movements induced by apomorphine in the 6-OHDA parkinsonian rat.
Annamaria Capozzo, Flora Vitale, Claudia Mattei, Paolo Mazzone, Eugenio Scarnati

Behav Brain Res· September 2014

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The temporal context of certainty-uncertainty modulates the subthalamic nucleus-mediated anticipatory responding.
Annamaria Capozzo, Claudia Mattei, Flora Vitale, Eugenio Scarnati

Behav Brain Res· June 2013

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