Publications by authors named "Florent Chuffart"

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A robust workflow to benchmark deconvolution of multi-omic data.
Elise Amblard, Vadim Bertrand, Hugo Barbot, Luis Martin Peña, Slim Karkar, Florent Chuffart

Genome Biol· December 2025

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Environmental exposure to endocrine disruptors induces insulin resistance and hepatic inflammation in adult male rats, with partial transmission across subsequent generations.
Marie Darracq-Ghitalla-Ciock, Nikita Rajkumari, Sylvie Veyrenc, Florent Chuffart, Stéphane Attia

Environ Pollut· November 2025

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Cardiac Sympathetic Denervation Mitigated Ischemic Cardiomyopathy Progression in a Rat Model of Sleep Apnea.
Maximin Détrait, Jonathan Gaucher, Emma Billoir, Sophie Bouyon, Emeline Lemarié, Florent Chuffart

J Am Heart Assoc· June 2025

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Discovery of epigenetically silenced tumour suppressor genes in aggressive breast cancer through a computational approach.
Anne-Laure Vitte, Florent Chuffart, Emmanuelle Jacquet, Eleni Nika, Mireille Mousseau

NAR Cancer· June 2025

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Mitochondrial dysfunction fuels drug resistance in adult T-cell acute lymphoblastic leukemia.
Shanshan Guo, Ekaterina Bourova-Flin, Sophie Rousseaux, Florent Chuffart, Lijun Peng

J Transl Med· May 2025

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Immediate and durable effects of maternal tobacco consumption on placental DNA methylation: a replication and discovery study.
Chloé Masdoumier, Lucile Broséus, Florent Chuffart, Olivier François, Ariane Guilbert

Environ Epigenet· May 2025

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HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients' clinical stage.
Lucile Dumolard, Theophile Gerster, Florent Chuffart, Thomas Decaens, Marie-Noelle Hilleret

Hepatol Commun· February 2025

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Clustering of variants into functional classes correlates with cancer risk and identifies different phenotypes of Li-Fraumeni syndrome.
Emilie Montellier, Nathanaël Lemonnier, Judith Penkert, Claire Freycon, Sandrine Blanchet, Florent Chuffart

iScience· December 2024

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Serum IGF1 Is a Prognostic Marker for Resistance to Targeted Therapies and a Predictive Marker for Anti-IGF1 Receptor Therapy in Melanoma.
Camila Castillo-Ferrer, Théo Marguet, Laetitia Vanwonterghem, Sule Erbek, Florent Chuffart

J Invest Dermatol· February 2024

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Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans.
Jonathan Gaucher, Emilie Montellier, Guillaume Vial, Florent Chuffart, Maëlle Guellerin

iScience· February 2024

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Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.
Domenico Iuso, Isabel Garcia-Saez, Yohann Couté, Yoshiki Yamaryo-Botté, Elisabetta Boeri Erba, Florent Chuffart

Sci Adv· September 2023

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Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers.
Emmanuelle Jacquet, Florent Chuffart, Anne-Laure Vitte, Eleni Nika, Mireille Mousseau

BMC Genomics· August 2023

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Luspatercept (RAP-536) modulates oxidative stress without affecting mutation burden in myelodysplastic syndromes.
Meunier Mathieu, Chloé Friedrich, Nicolas Ducrot, Johanna Zannoni, Tondeur Sylvie, Florent Chuffart

Ann Hematol· December 2022

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Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression.
Kalina Timcheva, Solenne Dufour, Leila Touat-Todeschini, Callum Burnard, Marie-Christine Carpentier, Florent Chuffart

Cell Rep· December 2022

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SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.
Valentina Lukinović, Simone Hausmann, Gael S Roth, Clement Oyeniran, Tanveer Ahmad, Florent Chuffart

Cancer Discov· September 2022

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Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia.
Mengping Xi, Shanshan Guo, Caicike Bayin, Lijun Peng, Florent Chuffart

Front Med· June 2022

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Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia.
Li-Jun Peng, Yue-Bo Zhou, Mei Geng, Ekaterina Bourova-Flin, Florent Chuffart

BMC Genomics· June 2022

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Chronic Intermittent Hypoxia Increases Cell Proliferation in Hepatocellular Carcinoma.
Lydie Carreres, Marion Mercey-Ressejac, Keerthi Kurma, Julien Ghelfi, Carole Fournier, Florent Chuffart

Cells· June 2022

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Direct visualization of pre-protamine 2 detects protamine assembly failures and predicts ICSI success.
Maryam Rezaei-Gazik, Alexandra Vargas, Amir Amiri-Yekta, Anne-Laure Vitte, Arvand Akbari, Florent Chuffart

Mol Hum Reprod· February 2022

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AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome.
Clovis Chabert, Anne-Laure Vitte, Domenico Iuso, Florent Chuffart, Candice Trocme

Int J Mol Sci· February 2022

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ATAD2 controls chromatin-bound HIRA turnover.
Tao Wang, Daniel Perazza, Fayçal Boussouar, Matteo Cattaneo, Alexandre Bougdour, Florent Chuffart

Life Sci Alliance· December 2021

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CCM2-deficient endothelial cells undergo a ROCK-dependent reprogramming into senescence-associated secretory phenotype.
Daphné Raphaëlle Vannier, Apeksha Shapeti, Florent Chuffart, Emmanuelle Planus, Sandra Manet

Angiogenesis· November 2021

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The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma.
Ekaterina Bourova-Flin, Samira Derakhshan, Afsaneh Goudarzi, Tao Wang, Anne-Laure Vitte, Florent Chuffart

Br J Cancer· October 2021

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DEN-Induced Rat Model Reproduces Key Features of Human Hepatocellular Carcinoma.
Keerthi Kurma, Olivier Manches, Florent Chuffart, Nathalie Sturm, Khaldoun Gharzeddine

Cancers (Basel)· October 2021

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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.
Mengqing Gao, Jin Wang, Sophie Rousseaux, Minjia Tan, Lulu Pan, Florent Chuffart

Cell Rep· July 2021

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