Publications by authors named "Florian Capito"

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Improving Downstream Process Related Manufacturability Based on Protein Engineering-A Feasibility Study.
Florian Capito, Ting Hin Wong, Christine Faust, Kilian Brand, Werner Dittrich

Eng Life Sci· September 2024

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Understanding virus retention mechanisms on protein a chromatography based on using different wash buffers - Evaluating the possibility for a generic wash buffer toolbox to improve virus clearance capacity.
Sandra Krause, Florian Capito, Verena Oeinck, Hendrik Flato, Holger Hoffmann

Biotechnol Notes· March 2024

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Mimicking continuous capture chromatography for virus clearance using a single chromatography column model.
Florian Capito, Hendrik Flato, Verena Oeinck, Stefan Dierl, Annette Berg

Biotechnol J· May 2022

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Moving to CoPACaPAnA: Implementation of a continuous protein A capture process for antibody applications within an end-to-end single-use GMP manufacturing downstream process.
Ozan Ötes, Cathrin Bernhardt, Kevin Brandt, Hendrik Flato, Otmar Klingler, Florian Capito

Biotechnol Rep (Amst)· June 2020

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Scale-up of continuous multicolumn chromatography for the protein a capture step: From bench to clinical manufacturing.
Ozan Ötes, Hendrik Flato, Daniel Vazquez Ramirez, Britta Badertscher, Marc Bisschops, Florian Capito

J Biotechnol· September 2018

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Feasibility of using continuous chromatography in downstream processing: Comparison of costs and product quality for a hybrid process vs. a conventional batch process.
Ozan Ötes, Hendrik Flato, Johannes Winderl, Jürgen Hubbuch, Florian Capito

J Biotechnol· October 2017

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Mid-infrared spectroscopy-based analysis of mammalian cell culture parameters.
Florian Capito, Aline Zimmer, Romas Skudas

Biotechnol Prog· January 2016

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Development of a univariate membrane-based mid-infrared method for protein quantitation and total lipid content analysis of biological samples.
Ivona Strug, Christopher Utzat, Amedeo Cappione, Sara Gutierrez, Ryan Amara, Florian Capito

J Anal Methods Chem· November 2014

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Customization of copolymers to optimize selectivity and yield in polymer-driven antibody purification processes.
Florian Capito, Romas Skudas, Bernd Stanislawski, Harald Kolmar

Biotechnol Prog· August 2014

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Feasibility of polyelectrolyte-driven Fab fragment separation.
Florian Capito, Harald Kolmar, Bianca Edelmann, Romas Skudas

Biotechnol J· May 2014

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Matrix effects during monitoring of antibody and host cell proteins using attenuated total reflection spectroscopy.
Florian Capito, Romas Skudas, Bernd Stanislawski, Harald Kolmar

Biotechnol Prog· January 2014

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Feasibility study of semi-selective protein precipitation with salt-tolerant copolymers for industrial purification of therapeutic antibodies.
Florian Capito, Johann Bauer, Almut Rapp, Christian Schröter, Harald Kolmar

Biotechnol Bioeng· November 2013

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Mid-infrared spectroscopy-based antibody aggregate quantification in cell culture fluids.
Florian Capito, Romas Skudas, Harald Kolmar, Christian Hunzinger

Biotechnol J· August 2013

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Host cell protein quantification by Fourier transform mid infrared spectroscopy (FT-MIR).
Florian Capito, Romas Skudas, Harald Kolmar, Bernd Stanislawski

Biotechnol Bioeng· January 2013

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