Publications by authors named "Florian Handle"

Claim this Profile
R
Repurposing Amiodarone for Bladder Cancer Treatment.
Francisco J Roa, Maria Roubelakis, Konstantinos Paschidis, Nils C H van Creij, Florian Handle

Cancer Res Commun· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The MicroRNA miR-454 and the mediator complex component MED12 are regulators of the androgen receptor pathway in prostate cancer.
Juan Guzman, Martin Hart, Katrin Weigelt, Angela Neumann, Achim Aigner, Florian Handle

Sci Rep· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression.
Jasper Van Goubergen, Miroslav Peřina, Florian Handle, Elisa Morales, Anika Kremer

Mol Oncol· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of the Sterol Regulatory Element Binding Protein SREBF-1 Overcomes Docetaxel Resistance in Advanced Prostate Cancer.
Maximilian P Brandt, Olesya Vakhrusheva, Hubert Hackl, Tamas Daher, Katrin Tagscherer, Florian Handle

Am J Pathol· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MED12 and CDK8/19 Modulate Androgen Receptor Activity and Enzalutamide Response in Prostate Cancer.
Chiara Andolfi, Caterina Bartolini, Elisa Morales, Büşra Gündoğdu, Martin Puhr, Florian Handle

Endocrinology· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rational evolution for altering the ligand preference of estrogen receptor alpha.
Roy Eerlings, Purvi Gupta, Xiao Yin Lee, Tien Nguyen, Sarah El Kharraz, Florian Handle

Protein Sci· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Glucocorticoid treatment influences prostate cancer cell growth and the tumor microenvironment via altered glucocorticoid receptor signaling in prostate fibroblasts.
Andrea Eigentler, Florian Handle, Silvia Schanung, Antonia Degen, Hubert Hackl

Oncogene· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization.
Tina Rauchenwald, Florian Handle, Catherine E Connolly, Antonia Degen, Christof Seifarth

Inflamm Regen· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Oncogenic Protein Kinase/ATPase RIOK1 Is Up-Regulated via the c-myc/E2F Transcription Factor Axis in Prostate Cancer.
Florian Handle, Martin Puhr, Martina Gruber, Chiara Andolfi, Georg Schäfer

Am J Pathol· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer.
Elien Smeets, Shengyun Huang, Xiao Yin Lee, Erika Van Nieuwenhove, Christine Helsen, Florian Handle

J Cachexia Sarcopenia Muscle· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer.
Thomas Van den Broeck, Lisa Moris, Thomas Gevaert, Elai Davicioni, Bram Boeckx, Florian Handle

Mol Cancer Res· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small-molecule profiling for steroid receptor activity using a universal steroid receptor reporter assay.
Roy Eerlings, Nana Barbakadze, Tien Nguyen, Nanuli Nadaraia, Elien Smeets, Florian Handle

J Steroid Biochem Mol Biol· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.
Sarah El Kharraz, Vanessa Dubois, Martin E van Royen, Adriaan B Houtsmuller, Ekatarina Pavlova, Florian Handle

EMBO Rep· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MYC-Mediated Ribosomal Gene Expression Sensitizes Enzalutamide-resistant Prostate Cancer Cells to EP300/CREBBP Inhibitors.
Tobias Furlan, Alexander Kirchmair, Natalie Sampson, Martin Puhr, Martina Gruber, Florian Handle

Am J Pathol· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the glucocorticoid receptor signature gene Mono Amine Oxidase-A enhances the efficacy of chemo- and anti-androgen therapy in advanced prostate cancer.
Martin Puhr, Andrea Eigentler, Florian Handle, Hubert Hackl, Christian Ploner

Oncogene· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical Models in Prostate Cancer: Resistance to AR Targeting Therapies in Prostate Cancer.
Wout Devlies, Florian Handle, Gaëtan Devos, Steven Joniau, Frank Claessens

Cancers (Basel)· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.
Holger H H Erb, Julia Bodenbender, Florian Handle, Tamara Diehl, Lukas Donix

PLoS One· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
p300 is upregulated by docetaxel and is a target in chemoresistant prostate cancer.
Martina Gruber, Lavinia Ferrone, Martin Puhr, Frédéric R Santer, Tobias Furlan, Florian Handle

Endocr Relat Cancer· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The stem cell inhibitor salinomycin decreases colony formation potential and tumor-initiating population in docetaxel-sensitive and docetaxel-resistant prostate cancer cells.
Martina Gruber, Florian Handle, Zoran Culig

Prostate· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells.
Florian Handle, Stefan Prekovic, Christine Helsen, Thomas Van den Broeck, Elien Smeets

Sci Rep· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AR variants: lost in translation to clinical practice?
Florian Handle, Frank Claessens

Nat Rev Urol· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fractionated Radiation of Primary Prostate Basal Cells Results in Downplay of Interferon Stem Cell and Cell Cycle Checkpoint Signatures.
Fabian Guggenberger, Harmen J G van de Werken, Holger H H Erb, Giuseppe Cappellano, Kristina Trattnig, Florian Handle

Eur Urol· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The STAT3 Inhibitor Galiellalactone Reduces IL6-Mediated AR Activity in Benign and Malignant Prostate Models.
Florian Handle, Martin Puhr, Georg Schaefer, Nicla Lorito, Julia Hoefer

Mol Cancer Ther· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effects of Intravitreal Aflibercept on Galectin-1 and Vascular Endothelial Growth Factor-A Plasma Levels in Patients with Diabetic Retinopathy.
Inga Waltl, Claus Zehetner, Christof Seifarth, Florian Handle, Gerhard F Kieselbach

Curr Eye Res· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Glucocorticoid Receptor Is a Key Player for Prostate Cancer Cell Survival and a Target for Improved Antiandrogen Therapy.
Martin Puhr, Julia Hoefer, Andrea Eigentler, Christian Ploner, Florian Handle

Clin Cancer Res· February 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis