Publications by authors named "Frances Edwards"

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Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer's disease mouse model.
Jack I Wood, Maciej Dulewicz, Alicja Szadziewska, Sophia Weiner, Junyue Ge, Frances A Edwards

Nat Commun· September 2025

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Isotope Encoded Spatial Biology Identifies Amyloid Plaque-Age-Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity.
Jack I Wood, Maciej Dulewicz, Junyue Ge, Katie Stringer, Alicja Szadziewska, Frances A Edwards

Res Sq· January 2025

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Age- and amyloid-β-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimer's disease without mutations in .
Sneha Desai, Elena Camporesi, Gunnar Brinkmalm, Argyro Alatza, Jack I Wood, Frances A Edwards

bioRxiv· November 2024

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Isotope Encoded chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity.
Jack I Wood, Maciej Dulewicz, Junyue Ge, Katie Stringer, Alicja Szadziewska, Frances A Edwards

bioRxiv· October 2024

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Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy.
Frances Edwards, Giulia Fantozzi, Anthony Y Simon, Jean-Philippe Morretton, Aurelie Herbette

PLoS Biol· September 2024

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Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics.
Punyawee Dulyayangkul, Thomas Beavis, Winnie W Y Lee, Robbie Ardagh, Frances Edwards

PLoS Pathog· June 2024

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Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly.
Nicolas Macaisne, Laura Bellutti, Kimberley Laband, Frances Edwards, Laras Pitayu-Nugroho

Elife· February 2023

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Impact of covid-19 vaccination on long covid.
Frances Edwards, Fergus W Hamilton

BMJ Med· February 2023

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Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology.
Jack I Wood, Eugenia Wong, Ridwaan Joghee, Aya Balbaa, Karina S Vitanova, Frances A Edwards

Cell Rep· November 2022

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Functional midbody assembly in the absence of a central spindle.
Sophia M Hirsch, Frances Edwards, Mimi Shirasu-Hiza, Julien Dumont, Julie C Canman

J Cell Biol· March 2022

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Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study.
Aisling M Chaney, Francisco R Lopez-Picon, Sophie Serrière, Rui Wang, Daniela Bochicchio, Frances A Edwards

Theranostics· August 2021

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Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia.
Diana P Benitez, Shenyi Jiang, Jack Wood, Rui Wang, Chloe M Hall, Frances A Edwards

Mol Neurodegener· July 2021

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Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.
Wojciech Michno, Katie M Stringer, Thomas Enzlein, Melissa K Passarelli, Stephane Escrig, Frances A Edwards

Sci Adv· June 2021

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Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
Wenfei Liu, Orjona Taso, Rui Wang, Sevinc Bayram, Andrew C Graham, Frances A Edwards

Hum Mol Genet· November 2020

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Chromosomes function as a barrier to mitotic spindle bipolarity in polyploid cells.
Alix Goupil, Maddalena Nano, Gaëlle Letort, Simon Gemble, Frances Edwards

J Cell Biol· April 2020

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Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment.
Rosellina Guarascio, Dervis Salih, Marina Yasvoina, Frances A Edwards, Michael E Cheetham

Hum Mol Genet· January 2020

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Clinical characteristics and treatment outcomes in a cohort of patients with pyogenic and amoebic liver abscess.
Lorna Neill, Frances Edwards, Simon M Collin, David Harrington, Dominic Wakerley

BMC Infect Dis· June 2019

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A Unifying Hypothesis for Alzheimer's Disease: From Plaques to Neurodegeneration.
Frances A Edwards

Trends Neurosci· May 2019

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Improving Mouse Models for Dementia. Are All the Effects in Tau Mouse Models Due to Overexpression?
Zelah Joel, Pablo Izquierdo, Dervis A Salih, Jill C Richardson, Damian M Cummings, Frances A Edwards

Cold Spring Harb Symp Quant Biol· February 2019

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Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APP/PSEN1 transgenic mice.
Evelyn Medawar, Tiffanie A Benway, Wenfei Liu, Taylor A Hanan, Peter Haslehurst, Frances A Edwards

EBioMedicine· January 2019

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Live imaging of C. elegans oocytes and early embryos.
Kimberley Laband, Benjamin Lacroix, Frances Edwards, Julie C Canman, Julien Dumont

Methods Cell Biol· December 2018

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BUB-1 promotes amphitelic chromosome biorientation via multiple activities at the kinetochore.
Frances Edwards, Gilliane Maton, Nelly Gareil, Julie C Canman, Julien Dumont

Elife· December 2018

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Chromosome segregation occurs by microtubule pushing in oocytes.
Kimberley Laband, Rémi Le Borgne, Frances Edwards, Marine Stefanutti, Julie C Canman

Nat Commun· November 2017

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Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood-Brain Barrier Failure.
Damian M Cummings, Tiffanie A Benway, Hinze Ho, Angelo Tedoldi, Monica M Fernandes Freitas, Frances A Edwards

Cereb Cortex· June 2017

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Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes.
Emmanuelle Gigant, Marine Stefanutti, Kimberley Laband, Agata Gluszek-Kustusz, Frances Edwards

Development· May 2017

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