Publications by authors named "Frances Shepherd"

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Mammalian antiviral proteins ZAP and KHNYN can independently restrict CpG-enriched avian viruses.
Jordan T Becker, Clayton K Mickelson, Lauren M Pross, Autumn E Sanders, Esther R Vogt, Frances K Shepherd

PLoS Biol· October 2025

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A retrospective analysis exploring the association of pretreatment neutrophil-to-lymphocyte ratio and immune checkpoint inhibitor outcomes in patients with advanced NSCLC and liver metastases.
Maisam Makarem, Tuan Hoang, Mitchell J Elliott, Andrew Rabinovitch, Katrina Hueniken, Frances A Shepherd

Ther Adv Med Oncol· October 2025

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Mammalian ZAP and KHNYN can independently restrict CpG-enriched avian viruses.
Jordan T Becker, Clayton K Mickelson, Lauren M Pross, Autumn E Sanders, Esther R Vogt, Frances K Shepherd

bioRxiv· September 2025

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Real-World Creatinine-Based Estimates of Acute and Chronic Kidney Dysfunction in Patients with Advanced ALK-Rearranged Non-Small-Cell Lung Cancer Receiving Tyrosine Kinase Inhibitors.
Louis Pinard, Avinash Rao Ullur, Louis Everest, Luna Jia Zhan, Rajeevan Selvaratnam, Frances A Shepherd

Clin Lung Cancer· September 2025

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Prognostic and predictive effects of TP53 co-mutation in patients with non-small cell lung cancer with rare treatable driver mutations.
Jamie Feng, Katrina Hueniken, Zhen Jason Fan, Luna Jia Zhan, Elizabeth Faour, Frances A Shepherd

Lung Cancer· June 2025

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Naturally transmitted mouse viruses highlight the heterogeneity of virus transmission dynamics in the dirty mouse model.
Dira S Putri, Frances K Shepherd, Autumn E Sanders, Shanley N Roach, Sridevi Jay

J Virol· June 2025

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Health Utility and Symptom Scores in Patients With Advanced Malignant Pleural Mesothelioma Treated in a Real-World Setting.
Abhenil Mittal, Louis Everest, Devalben Patel, Luna J Zhan, M Catherine Brown, Frances A Shepherd

JTO Clin Res Rep· June 2025

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Myasthenia Gravis in Patients Treated With Immune Checkpoint Inhibitors.
Abdulrahman Alghabban, Lucy Corke, Hans Katzberg, Vera Bril, Carolina Barnett-Tapia, Frances A Shepherd

JTO Clin Res Rep· May 2025

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A plain language summary of results from the FLAURA2 study: Effects of initial (first-line) osimertinib plus chemotherapy on the brain in patients with EGFR-mutated advanced non-small cell lung cancer.
Pasi A Jänne, David Planchard, Kunihiko Kobayashi, Ying Cheng, Chee Khoon Lee, Frances A Shepherd

Future Oncol· April 2025

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Real-world outcomes of prophylactic cranial irradiation utilization and efficacy for patients with extensive-stage small cell lung cancer treated with consolidative thoracic radiotherapy.
Abdul H Lone, Rohan Salunkhe, Vijithan Sugumar, Luna J Zhan, Xiang Y Ye, Frances A Shepherd

Clin Transl Radiat Oncol· March 2025

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Retrospective cohort study assessing clinical outcomes of patients with extensive-stage small cell lung cancer treated with and without consolidative thoracic radiotherapy at the Princess Margaret Cancer Centre.
Vijithan Sugumar, Rohan Salunkhe, Hadee Lone, Xiang Ye, Luna Zhan, Frances Shepherd

BMJ Open· March 2025

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Adaptive Universal Principles for Real-world Observational Studies (AUPROS): an approach to designing real-world observational studies for clinical, epidemiologic, and precision oncology research.
Samir H Barghout, Nicholas Meti, Simren Chotai, Christina J H Kim, Devalben Patel, Frances A Shepherd

Br J Cancer· February 2025

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Consolidation ALK Tyrosine Kinase Inhibitors Versus Durvalumab or Observation After Chemoradiation in Unresectable Stage III ALK-Positive NSCLC.
Amin H Nassar, Ritujith Jayakrishnan, Jamie Feng, Frances Shepherd, Elio Adib

J Thorac Oncol· January 2025

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Assessing the feasibility and external validity of natural language processing-extracted data for advanced lung cancer patients.
Yuchen Li, Jennifer Law, Lisa W Le, Janice J N Li, Christopher Pettengell, Frances A Shepherd

Lung Cancer· January 2025

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Analysis of outcomes in resected early-stage NSCLC with rare targetable driver mutations.
Nadia Ghazali, Jamie Feng, Katrina Hueniken, Khaleeq Khan, Karmugi Balaratnam, Frances A Shepherd

Ther Adv Med Oncol· December 2024

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Immediate Versus Deferred Systemic Therapy in Patients With Mesothelioma.
Sabine Schmid, Luna Zhan, Miguel Garcia, Kristen Dietrich, Khaleeq Khan, Frances A Shepherd

Clin Lung Cancer· November 2024

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Correction: Spartalizumab in combination with platinum-doublet chemotherapy with or without canakinumab in patients with PD-L1-unselected, metastatic NSCLC.
Armando Santoro, Garrido Pilar, Daniel S W Tan, Jon Zugazagoitia, Frances A Shepherd

BMC Cancer· November 2024

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Experimental viral spillover across 25 million year gap in Rodentia reveals limited viral transmission and purifying selection of a picornavirus.
Frances K Shepherd, Shanley N Roach, Autumn E Sanders, Yanan Liu, Dira S Putri

mBio· October 2024

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Spartalizumab in combination with platinum-doublet chemotherapy with or without canakinumab in patients with PD-L1-unselected, metastatic NSCLC.
Armando Santoro, Garrido Pilar, Daniel S W Tan, Jon Zugazagoitia, Frances A Shepherd

BMC Cancer· October 2024

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Outcomes with non-small cell lung cancer and brain-only metastasis.
Sabine Schmid, Miguel Garcia, Luna Zhan, Sierra Cheng, Khaleeq Khan, Frances A Shepherd

Heliyon· September 2024

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Treatment patterns and outcomes in KRAS-positive advanced NSCLC patients previously treated with immune checkpoint inhibitors: A Canada-wide real-world, multi-center, retrospective cohort study.
Samir H Barghout, Luna Jia Zhan, Starvroula Raptis, Faisal Al-Agha, Niki Esfahanian, Frances A Shepherd

Lung Cancer· August 2024

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Repeat Next-Generation Sequencing (15-Gene Panel) in Unifocal, Synchronous, and Metachronous Non-Small-Cell Lung Cancer-A Single-Center Experience.
Shelley Kuang, Kaitlin Chen, Sachin Sayal, Gajeni Prabahan, Mary R Rabey, Frances A Shepherd

Curr Oncol· August 2024

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Tropism for ciliated cells is the dominant driver of influenza viral burst size in the human airway.
Shanley N Roach, Frances K Shepherd, Clayton K Mickelson, Jessica K Fiege, Beth K Thielen

Proc Natl Acad Sci U S A· July 2024

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Real-World Outcomes of Patients with Advanced Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer in Canada Using Data Extracted by Large Language Model-Based Artificial Intelligence.
Ruth Moulson, Jennifer Law, Adrian Sacher, Geoffrey Liu, Frances A Shepherd

Curr Oncol· April 2024

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Summary of Research: Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC.
Masahiro Tsuboi, Roy S Herbst, Thomas John, Terufumi Kato, Margarita Majem, Frances A Shepherd

Target Oncol· March 2024

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