Publications by authors named "Francesca Clemente"

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Selenoureido-N-alkyl-3,4,5-trihydroxypiperidines: probing their dual-target role in Gaucher disease.
Debora Pratesi, Francesca Clemente, Camilla Matassini, Silvia Falliano, Amelia Morrone

Bioorg Med Chem· January 2026

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Simultaneous Grafting of 3,4,5-Trihydroxypiperidine Iminosugars Onto Multivalent Scaffolds via Double Reductive Amination Provides New GCase Inhibitors.
Maria Giulia Davighi, Francesca Clemente, Alessio Morano, Francesca Mangiavacchi, Francesca Cardona

Chemistry· December 2025

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Cisplatin and temozolomide combinatorial treatment triggers hypermutability and immune surveillance in experimental cancer models.
Pietro Paolo Vitiello, Benoit Rousseau, Rosaria Chilà, Paolo Battuello, Vito Amodio, Francesca Clemente

Cancer Cell· July 2025

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Acetal functionalized iminosugars for targeting β-glucocerebrosidase modulation.
Maria Giulia Davighi, Francesca Clemente, Camilla Matassini, Martina Cacciarini, Damiano Tanini

Eur J Med Chem· June 2025

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Molecular Basis of pv Levansucrase Inhibition by a Multivalent Iminosugar.
Costanza Cicchi, Luigia Pazzagli, Paolo Paoli, Sara Campigli, Guido Marchi, Francesca Clemente

J Agric Food Chem· June 2025

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Exploring Multivalent Architectures for Binding and Stabilization of -Acetylgalactosamine 6-Sulfatase.
Maria Giulia Davighi, Francesca Clemente, Giampiero D'Adamio, Macarena Martínez-Bailén, Alessio Morano

Molecules· May 2025

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Evidence of α-Synuclein/Glucocerebrosidase Dual Targeting by Iminosugar Derivatives.
Giuseppe Tagliaferro, Maria Giulia Davighi, Francesca Clemente, Filippo Turchi, Marco Schiavina

ACS Chem Neurosci· April 2025

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Unravelling Plasma Extracellular Vesicle Diversity With Optimised Spectral Flow Cytometry.
Daniela Boselli, Francesca Clemente, Simona Di Terlizzi, Christina Pagiatakis, Laura Papa

J Extracell Biol· April 2025

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Multivalent GCase Enhancers: Synthesis and Evaluation of Glyco-Gold Nanoparticles Decorated with Trihydroxypiperidine Iminosugars.
Francesca Buco, Francesca Clemente, Amelia Morrone, Costanza Vanni, Sergio E Moya

Bioconjug Chem· January 2025

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Iminosugar-Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers.
Maria Giulia Davighi, Francesca Clemente, Emilie Sperling Andreasen, Mogens Brøndsted Nielsen, Camilla Matassini

Chem Biodivers· August 2024

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Characterization of human CD4EOMESGzmK T-cell subsets unveils an uncoupling of suppressive functions from IL-10-producing capacities.
Nadia Pulvirenti, Ylenia Silvetri, Francesca Clemente, Roberto Bosotti, Elena Carelli

Eur J Immunol· April 2024

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Tracking the immune response profiles elicited by the BNT162b2 vaccine in COVID-19 unexperienced and experienced individuals.
Eugenia Galeota, Valeria Bevilacqua, Andrea Gobbini, Paola Gruarin, Mauro Bombaci, Francesca Clemente

Clin Immunol· April 2024

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pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene.
Maria Giulia Davighi, Camilla Matassini, Francesca Clemente, Paolo Paoli, Amelia Morrone

Chembiochem· January 2024

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Identification of GM1-Ganglioside Secondary Accumulation in Fibroblasts from Neuropathic Gaucher Patients and Effect of a Trivalent Trihydroxypiperidine Iminosugar Compound on Its Storage Reduction.
Costanza Ceni, Francesca Clemente, Francesca Mangiavacchi, Camilla Matassini, Rodolfo Tonin

Molecules· January 2024

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An Intestinal Th17 Subset is Associated with Inflammation in Crohn's Disease and Activated by Adherent-invasive Escherichia coli.
Moira Paroni, Gabriella Leccese, Valeria Ranzani, Giorgia Moschetti, Matteo Chiara, Francesca Clemente

J Crohns Colitis· December 2023

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Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme -acetylgalactosamine-6-sulfatase (GALNS).
Francesca Buco, Camilla Matassini, Costanza Vanni, Francesca Clemente, Paolo Paoli

Org Biomol Chem· December 2023

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Pro-tumor Tfh2 cells induce detrimental IgG4 production and PGE-dependent IgE inhibition in pancreatic cancer.
Lucia De Monte, Francesca Clemente, Eliana Ruggiero, Raffaella Pini, Maria Grazia Ceraolo

EBioMedicine· November 2023

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SARS-COV-2 specific t-cells in patients with thyroid disorders related to COVID-19 are enriched in the thyroid and acquire a tissue-resident memory phenotype.
Ylenia Silvestri, Francesca Clemente, Giorgia Moschetti, Sara Maioli, Elena Carelli

Clin Immunol· September 2023

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Stereoselective Synthesis of Heavily Hydroxylated Azepane Iminosugars via Osmium-Catalyzed Tethered Aminohydroxylation.
Macarena Martínez-Bailén, Camilla Matassini, Francesca Clemente, Cristina Faggi, Andrea Goti

Org Lett· August 2023

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Immunomodulatory Effects of Endoscopic Ultrasound-Guided Thermal Ablation in Patients with Pancreatic Ductal Adenocarcinoma.
Sabrina Gloria Giulia Testoni, Claudia Minici, Elisa Benetti, Francesca Clemente, Daniela Boselli

Cancers (Basel)· July 2023

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Eomesodermin-expressing type 1 regulatory (EOMES Tr1)-like T cells: Basic biology and role in immune-mediated diseases.
Jens Geginat, Chiara Vasco, Paola Gruarin, Raoul Bonnal, Grazisa Rossetti, Francesca Clemente

Eur J Immunol· May 2023

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Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones.
Francesca Clemente, Maria Giulia Davighi, Camilla Matassini, Francesca Cardona, Andrea Goti

Chemistry· April 2023

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Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases.
Cristina Faccani, Gianluca Rotta, Francesca Clemente, Maya Fedeli, Danilo Abbati

Life Sci Alliance· October 2022

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GCase Enhancers: A Potential Therapeutic Option for Gaucher Disease and Other Neurological Disorders.
Macarena Martínez-Bailén, Francesca Clemente, Camilla Matassini, Francesca Cardona

Pharmaceuticals (Basel)· July 2022

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Synthesis of a New β-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis.
Francesca Clemente, Macarena Martínez-Bailén, Camilla Matassini, Amelia Morrone, Silvia Falliano

Molecules· June 2022

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