Publications by authors named "Francesca D Ciccarelli"

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Tumor microenvironments with an active type I IFN response are sensitive to inhibitors of heme degradation.
Dominika Sosnowska, Tik Shing Cheung, Jit Sarkar, James W Opzoomer, Karen T Feehan, Francesca D Ciccarelli

JCI Insight· August 2025

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A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer.
Amelia Acha-Sagredo, Pietro Andrei, Kalum Clayton, Emma Taggart, Carlotta Antoniotti, Francesca D Ciccarelli

Cancer Cell· February 2025

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Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer.
Piyali Ganguli, Celia C Basanta, Amelia Acha-Sagredo, Hrvoje Misetic, Maria Armero, Francesca D Ciccarelli

Nat Cancer· January 2025

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Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue.
Lucia Montorsi, Michael J Pitcher, Yuan Zhao, Chiara Dionisi, Alicia Demonti, Francesca D Ciccarelli

Nat Commun· May 2024

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Apoptosis in mesenchymal stromal cells activates an immunosuppressive secretome predicting clinical response in Crohn's disease.
Tik Shing Cheung, Chiara Giacomini, Matteo Cereda, Alvaro Avivar-Valderas, Daria Capece, Francesca D Ciccarelli

Mol Ther· December 2023

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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes.
Anastasiya Kazachenka, Jane Hc Loong, Jan Attig, George R Young, Piyali Ganguli, Francesca D Ciccarelli

NAR Cancer· September 2023

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Mechanistic insights into the interactions between cancer drivers and the tumour immune microenvironment.
Hrvoje Misetic, Mohamed Reda Keddar, Jean-Pierre Jeannon, Francesca D Ciccarelli

Genome Med· June 2023

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Reflected stemness as a potential driver of the tumour microenvironment.
Felipe S Rodrigues, Francesca D Ciccarelli, Ilaria Malanchi

Trends Cell Biol· December 2022

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Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers: A pilot study.
Ella F Gunady, Kathryn E Ware, Sarah Hoskinson Plumlee, Nicolas Devos, David Corcoran, Francesca D Ciccarelli

Evol Med Public Health· April 2022

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A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution.
Michele Bortolomeazzi, Lucia Montorsi, Damjan Temelkovski, Mohamed Reda Keddar, Amelia Acha-Sagredo, Francesca D Ciccarelli

Nat Commun· February 2022

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Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource.
Lisa Dressler, Michele Bortolomeazzi, Mohamed Reda Keddar, Hrvoje Misetic, Giulia Sartini, Francesca D Ciccarelli

Genome Biol· January 2022

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Clone competition as a mechanism to reduce tumor formation.
Amelia Acha-Sagredo, Ilaria Malanchi, Francesca D Ciccarelli

Dev Cell· December 2021

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Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts.
Michele Bortolomeazzi, Mohamed Reda Keddar, Lucia Montorsi, Amelia Acha-Sagredo, Lorena Benedetti, Francesca D Ciccarelli

Gastroenterology· October 2021

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O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR.
Virginia Tajadura-Ortega, Gennaro Gambardella, Alexandra Skinner, Adnan Halim, Julie Van Coillie, Francesca D Ciccarelli

Glycobiology· April 2021

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Normal Somatic Mutations in Cancer Transformation.
Neshika Wijewardhane, Lisa Dressler, Francesca D Ciccarelli

Cancer Cell· February 2021

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Pan-cancer detection of driver genes at the single-patient resolution.
Joel Nulsen, Hrvoje Misetic, Christopher Yau, Francesca D Ciccarelli

Genome Med· February 2021

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Approaching Cancer Evolution from Different Angles.
Francesca D Ciccarelli, James DeGregori

iScience· November 2020

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Identification of non-cancer cells from cancer transcriptomic data.
Michele Bortolomeazzi, Mohamed Reda Keddar, Francesca D Ciccarelli, Lorena Benedetti

Biochim Biophys Acta Gene Regul Mech· June 2020

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IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis.
Marika Catapano, Marta Vergnano, Marco Romano, Satveer K Mahil, Siew-Eng Choon, Francesca D Ciccarelli

J Invest Dermatol· April 2020

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Molecular Biology and Evolution of Cancer: From Discovery to Action.
Jason A Somarelli, Heather Gardner, Vincent L Cannataro, Ella F Gunady, Amy M Boddy, Francesca D Ciccarelli

Mol Biol Evol· February 2020

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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.
Thanos P Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Francesca D Ciccarelli

Nat Commun· July 2019

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The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens.
Dimitra Repana, Joel Nulsen, Lisa Dressler, Michele Bortolomeazzi, Santhilata Kuppili Venkata, Francesca D Ciccarelli

Genome Biol· January 2019

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Mutations differ in normal and cancer cells of the oesophagus.
Francesca D Ciccarelli

Nature· January 2019

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Mapping the Human Kinome in Response to DNA Damage.
Michel Owusu, Peter Bannauer, Joana Ferreira da Silva, Thanos P Mourikis, Alistair Jones, Francesca D Ciccarelli

Cell Rep· January 2019

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An analysis of IL-36 signature genes and individuals with knockout mutations validates IL-36 as a psoriasis therapeutic target.
Satveer K Mahil, Marika Catapano, Paola Di Meglio, Nick Dand, Helena Ahlfors, Francesca D Ciccarelli

Sci Transl Med· October 2017

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