Publications by authors named "Francesca Marcoccia"

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Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
Alice Legru, Federica Verdirosa, Yen Vo-Hoang, Giusy Tassone, Filippo Vascon, Francesca Marcoccia

J Med Chem· December 2022

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Discovery of , a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and .
David T Davies, Simon Leiris, Magdalena Zalacain, Nicolas Sprynski, Jérôme Castandet, Francesca Marcoccia

J Med Chem· December 2020

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ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing .
David T Davies, Simon Leiris, Nicolas Sprynski, Jérôme Castandet, Clarisse Lozano, Francesca Marcoccia

ACS Infect Dis· September 2020

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4-(-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition.
Laurent Gavara, Federica Verdirosa, Alice Legru, Paola Sandra Mercuri, Lionel Nauton, Francesca Marcoccia

Biomolecules· July 2020

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A Kinetic Study of the Replacement by Site Saturation Mutagenesis of Residue 119 in NDM-1 Metallo-β-Lactamase.
Francesca Marcoccia, Paola Sandra Mercuri, Moreno Galleni, Giuseppe Celenza, Gianfranco Amicosante

Antimicrob Agents Chemother· August 2018

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Exploring the role of L209 residue in the active site of NDM-1 a metallo-β-lactamase.
Francesca Marcoccia, Hanna-Kirsti S Leiros, Massimiliano Aschi, Gianfranco Amicosante, Mariagrazia Perilli

PLoS One· February 2018

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Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1.
Francesca Spyrakis, Giuseppe Celenza, Francesca Marcoccia, Matteo Santucci, Simon Cross

ACS Med Chem Lett· January 2018

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Interaction of carbapenems and β-lactamase inhibitors towards CTX-M-15 and CTX-M-15 mutant.
Alessia Sabatini, Fabrizia Brisdelli, Giuseppe Celenza, Francesca Marcoccia, Martina Colapietro

J Glob Antimicrob Resist· September 2017

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Ceftaroline in vitro activity against methicillin-resistant Staphylococcus aureus and coagulase-negative Staphylococci: a short report from Italy.
Bernardetta Segatore, Domenico Setacci, Francesca Marcoccia, Gianfranco Amicosante

J Chemother· April 2017

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BlaB-15, a new BlaB metallo-β-lactamase variant found in an Elizabethkingia miricola clinical isolate.
Martina Colapietro, Andrea Endimiani, Alessia Sabatini, Francesca Marcoccia, Giuseppe Celenza

Diagn Microbiol Infect Dis· June 2016

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Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems.
Carlo Bottoni, Mariagrazia Perilli, Francesca Marcoccia, Alessandra Piccirilli, Cristina Pellegrini

Antimicrob Agents Chemother· May 2016

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Kinetic Study of Laboratory Mutants of NDM-1 Metallo-β-Lactamase and the Importance of an Isoleucine at Position 35.
Francesca Marcoccia, Carlo Bottoni, Alessia Sabatini, Martina Colapietro, Paola Sandra Mercuri

Antimicrob Agents Chemother· April 2016

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Identification of New Natural CphA Metallo-β-Lactamases CphA4 and CphA5 in Aeromonas veronii and Aeromonas hydrophila Isolates from Municipal Sewage in Central Italy.
Carlo Bottoni, Francesca Marcoccia, Chiara Compagnoni, Martina Colapietro, Alessia Sabatini

Antimicrob Agents Chemother· August 2015

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OXA-23 carbapenemase in multidrug-resistant Acinetobacter baumannii ST2 type: first identification in L'Aquila Hospital (Italy).
Mariagrazia Perilli, Alessia Sabatini, Eugenio Pontieri, Giuseppe Celenza, Bernardetta Segatore, Francesca Marcoccia

Microb Drug Resist· February 2015

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