Publications by authors named "Francesco Bossa"

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Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors.
Frederick Daidone, Riccardo Montioli, Alessandro Paiardini, Barbara Cellini, Antonio Macchiarulo, Francesco Bossa

PLoS One· August 2012

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PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL.
Emanuele Bramucci, Alessandro Paiardini, Francesco Bossa, Stefano Pascarella

BMC Bioinformatics· March 2012

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In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed.
Frederick Daidone, Rita Florio, Serena Rinaldo, Roberto Contestabile, Martino L di Salvo, Francesco Bossa

Eur J Med Chem· May 2011

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Structural adaptation of serine hydroxymethyltransferase to low temperatures.
Alessandro Siglioccolo, Francesco Bossa, Stefano Pascarella

Int J Biol Macromol· January 2010

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Structural stability of the cofactor binding site in Escherichia coli serine hydroxymethyltransferase--the role of evolutionarily conserved hydrophobic contacts.
Rita Florio, Roberta Chiaraluce, Valerio Consalvi, Alessandro Paiardini, Bruno Catacchio, Francesco Bossa

FEBS J· December 2009

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Mutation of His465 alters the pH-dependent spectroscopic properties of Escherichia coli glutamate decarboxylase and broadens the range of its activity toward more alkaline pH.
Eugenia Pennacchietti, Tijs M Lammens, Guido Capitani, Maurice C R Franssen, Robert A John, Francesco Bossa

J Biol Chem· November 2009

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Structural adaptation of the subunit interface of oligomeric thermophilic and hyperthermophilic enzymes.
Elisa Maugini, Daniele Tronelli, Francesco Bossa, Stefano Pascarella

Comput Biol Chem· April 2009

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The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase.
Rita Florio, Roberta Chiaraluce, Valerio Consalvi, Alessandro Paiardini, Bruno Catacchio, Francesco Bossa

FEBS J· January 2009

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"Hot cores" in proteins: comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms.
Alessandro Paiardini, Riccardo Sali, Francesco Bossa, Stefano Pascarella

BMC Struct Biol· February 2008

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Structural adaptation to low temperatures--analysis of the subunit interface of oligomeric psychrophilic enzymes.
Daniele Tronelli, Elisa Maugini, Francesco Bossa, Stefano Pascarella

FEBS J· September 2007

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The mechanism of addition of pyridoxal 5'-phosphate to Escherichia coli apo-serine hydroxymethyltransferase.
Francesca Malerba, Andrea Bellelli, Alessandra Giorgi, Francesco Bossa, Roberto Contestabile

Biochem J· June 2007

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Pyridoxal 5'-phosphate enzymes as targets for therapeutic agents.
Alessio Amadasi, Mariarita Bertoldi, Roberto Contestabile, Stefano Bettati, Barbara Cellini, Francesco Bossa

Curr Med Chem· June 2007

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Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB.
Heinz Gut, Eugenia Pennacchietti, Robert A John, Francesco Bossa, Guido Capitani

EMBO J· June 2006

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CAMPO, SCR_FIND and CHC_FIND: a suite of web tools for computational structural biology.
Alessandro Paiardini, Francesco Bossa, Stefano Pascarella

Nucleic Acids Res· July 2005

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Evolutionarily conserved regions and hydrophobic contacts at the superfamily level: The case of the fold-type I, pyridoxal-5'-phosphate-dependent enzymes.
Alessandro Paiardini, Francesco Bossa, Stefano Pascarella

Protein Sci· November 2004

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Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin.
Paola Storici, Daniela De Biase, Francesco Bossa, Stefano Bruno, Andrea Mozzarelli

J Biol Chem· January 2004

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Improvement in prediction of solvent accessibility by probability profiles.
Giulio Gianese, Francesco Bossa, Stefano Pascarella

Protein Eng· December 2003

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The critical structural role of a highly conserved histidine residue in group II amino acid decarboxylases.
Guido Capitani, Angela Tramonti, Francesco Bossa, Markus G Grütter, Daniela De Biase

FEBS Lett· November 2003

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Catalytic and thermodynamic properties of tetrahydromethanopterin-dependent serine hydroxymethyltransferase from Methanococcus jannaschii.
Sebastiana Angelaccio, Roberta Chiaraluce, Valerio Consalvi, Bärbel Buchenau, Laura Giangiacomo, Francesco Bossa

J Biol Chem· October 2003

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Crystal structure and functional analysis of Escherichia coli glutamate decarboxylase.
Guido Capitani, Daniela De Biase, Caterina Aurizi, Heinz Gut, Francesco Bossa

EMBO J· August 2003

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D-amino acid analysis.
Andrea Scaloni, Maurizio Simmaco, Francesco Bossa

Methods Mol Biol· May 2003

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Structure and mechanism of Escherichia coli pyridoxine 5'-phosphate oxidase.
Martino L di Salvo, Martin K Safo, Faik N Musayev, Francesco Bossa, Verne Schirch

Biochim Biophys Acta· April 2003

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Threonine aldolase and alanine racemase: novel examples of convergent evolution in the superfamily of vitamin B6-dependent enzymes.
Alessandro Paiardini, Roberto Contestabile, Simona D'Aguanno, Stefano Pascarella, Francesco Bossa

Biochim Biophys Acta· April 2003

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Structural plasticity of thermophilic serine hydroxymethyltransferases.
Alessandro Paiardini, Giulio Gianese, Francesco Bossa, Stefano Pascarella

Proteins· January 2003

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Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli.
Angela Tramonti, Robert A John, Francesco Bossa, Daniela De Biase

Eur J Biochem· October 2002

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