Publications by authors named "Francesco Dituri"

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Proteoglycan-4 potentiates the antitumor efficacy of regorafenib in an orthotopic model of hepatocellular carcinoma.
Livianna Carrieri, Anas Munir, Giusi Caragnano, Davide Guido, Grazia Serino, Francesco Dituri

J Exp Clin Cancer Res· December 2025

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New Experimental Mouse Models to Evaluate the Role of Transforming Growth Factor-Beta in Liver Tumorigenesis.
Ana Cantos-Cortes, Josep Amengual, Rut Espinosa-Sotelo, Esther Bertran, Javier Vaquero, Francesco Dituri

Liver Int· October 2025

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Inorganic Polyphosphate Triggers NLRP3 Inflammasome and Promotes the Epithelial-to-Mesenchymal Transition and Migration of Colorectal Cancer Cells Through TRPM8 Receptor.
Valentina Arrè, Maria Principia Scavo, Rossella Donghia, Francesco Dituri, Camilla Mandorino

Int J Mol Sci· August 2025

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Dual Inhibition of SRC Family Kinases and Sorafenib Enhances Anti-Tumor Activity in Hepatocellular Carcinoma Cells.
Loraine Kay Cabral, Cyrollah Disoma, Paola Tarchi, Korri Elvanita El-Khobar, Agustiningsih Agustiningsih, Francesco Dituri

Int J Mol Sci· July 2025

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Inhibiting the TGF-β1 Pathway Reduces the Aggressiveness of Intrahepatic CCA HuCCT1 CD90-Positive Cells.
Elena Pizzuto, Serena Mancarella, Isabella Gigante, Grazia Serino, Francesco Dituri

Int J Mol Sci· May 2025

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New Hepatocellular Carcinoma (HCC) Primary Cell Cultures as Models for Exploring Personalized Anti-TGF-β Therapies Based on Tumor Characteristics.
Rosanna Scialpi, Rut Espinosa-Sotelo, Esther Bertran, Francesco Dituri, Gianluigi Giannelli

Int J Mol Sci· March 2025

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Targeting cancer-associated fibroblasts/tumor cells cross-talk inhibits intrahepatic cholangiocarcinoma progression via cell-cycle arrest.
Serena Mancarella, Isabella Gigante, Elena Pizzuto, Grazia Serino, Alberta Terzi, Francesco Dituri

J Exp Clin Cancer Res· October 2024

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The Neoangiogenic Transcriptomic Signature Impacts Hepatocellular Carcinoma Prognosis and Can Be Triggered by Transarterial Chemoembolization Treatment.
Rosina Maria Critelli, Federico Casari, Alberto Borghi, Grazia Serino, Cristian Caporali, Francesco Dituri

Cancers (Basel)· October 2024

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Inorganic Polyphosphate Promotes Colorectal Cancer Growth via TRPM8 Receptor Signaling Pathway.
Valentina Arrè, Francesco Balestra, Rosanna Scialpi, Francesco Dituri, Rossella Donghia

Cancers (Basel)· September 2024

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Differential Impact of Tumor Endothelial Angiopoietin-2 and Podoplanin in Lymphatic Endothelial Cells on HCC Outcomes with Tyrosine Kinase Inhibitor Treatment According to Sex.
Simone Lasagni, Rosina Maria Critelli, Fabiola Milosa, Dario Saltini, Filippo Schepis, Francesco Dituri

Biomedicines· June 2024

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Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids.
Adriana Romanzi, Fabiola Milosa, Gemma Marcelli, Rosina Maria Critelli, Simone Lasagni, Francesco Dituri

Biomedicines· December 2023

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Perinatal asphyxia and hypothermic treatment from the endocrine perspective.
Nicola Improda, Donatella Capalbo, Antonella Poloniato, Gisella Garbetta, Francesco Dituri

Front Endocrinol (Lausanne)· November 2023

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Artificial Intelligence and Complex Network Approaches Reveal Potential Gene Biomarkers for Hepatocellular Carcinoma.
Antonio Lacalamita, Grazia Serino, Ester Pantaleo, Alfonso Monaco, Nicola Amoroso, Francesco Dituri

Int J Mol Sci· October 2023

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Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma.
Rut Espinosa-Sotelo, Noel P Fusté, Irene Peñuelas-Haro, Ania Alay, Gabriel Pons, Francesco Dituri

Redox Biol· September 2023

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Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models.
Matteo Centonze, Giusy Di Conza, Michael Lahn, Isabel Fabregat, Francesco Dituri

J Exp Clin Cancer Res· August 2023

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Correction: Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models.
Matteo Centonze, Giusy Di Conza, Michael Lahn, Isabel Fabregat, Francesco Dituri

J Exp Clin Cancer Res· August 2023

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PD-L1 Downregulation and DNA Methylation Inhibition for Molecular Therapy against Cancer Stem Cells in Hepatocellular Carcinoma.
Caecilia Sukowati, Loraine Kay D Cabral, Beatrice Anfuso, Francesco Dituri, Roberto Negro

Int J Mol Sci· August 2023

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Facial clues to the photosensitive trichothiodystrophy phenotype in childhood.
Giulia Pascolini, Federica Gaudioso, Marina Baldi, Dario Alario, Francesco Dituri

J Hum Genet· June 2023

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Laminin-332 γ2 Monomeric Chain Promotes Adhesion and Migration of Hepatocellular Carcinoma Cells.
Rosanna Scialpi, Valentina Arrè, Gianluigi Giannelli, Francesco Dituri

Cancers (Basel)· January 2023

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Network Analysis for the Discovery of Common Oncogenic Biomarkers in Liver Cancer Experimental Models.
Loraine Kay D Cabral, Pablo J Giraudi, Gianluigi Giannelli, Francesco Dituri, Roberto Negro

Biomedicines· January 2023

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Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma.
Rosina Maria Critelli, Fabiola Milosa, Adriana Romanzi, Simone Lasagni, Gemma Marcelli, Francesco Dituri

Oncol Lett· November 2022

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Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahepatic CCA viaTGF-β inhibition.
Serena Mancarella, Isabella Gigante, Grazia Serino, Elena Pizzuto, Francesco Dituri

J Exp Clin Cancer Res· November 2022

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Endothelial angiopoietin-2 overexpression in explanted livers identifies subjects at higher risk of recurrence of hepatocellular carcinoma after liver transplantation.
Simone Lasagni, Filippo Leonardi, Alessandra Pivetti, Lorenza Di Marco, Federico Ravaioli, Francesco Dituri

Front Oncol· September 2022

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Proteoglycans in Cancer: Friends or Enemies? A Special Focus on Hepatocellular Carcinoma.
Francesco Dituri, Gianluigi Gigante, Rosanna Scialpi, Serena Mancarella, Isabel Fabregat

Cancers (Basel)· April 2022

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The Tumor Microenvironment Drives Intrahepatic Cholangiocarcinoma Progression.
Serena Mancarella, Grazia Serino, Sergio Coletta, Raffaele Armentano, Francesco Dituri

Int J Mol Sci· April 2022

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