Publications by authors named "Francesco Saccoliti"

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Exploring structure-activity relationships of pyrrolyl diketo acid derivatives as non-nucleoside inhibitors of terminal deoxynucleotidyl transferase enzyme.
Valentina Noemi Madia, Nadia Garibaldi, Davide Ialongo, Elisa Patacchini, Valeria Tudino, Francesco Saccoliti

J Enzyme Inhib Med Chem· December 2025

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Molecular targeting of the deubiquitinase USP14 to circumvent cisplatin resistance in ovarian carcinoma and identification of novel inhibitors.
Cristina Corno, Debora Russo, Francesco Pignotti, Francesca De Giorgi, Ilaria Penna, Francesco Saccoliti

Cancer Drug Resist· October 2025

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-alkyl and -benzyl indoles are anti-SARS-CoV-2 agents and nsp13 inhibitors.
Aurora Albano, Roberta Emmolo, Riccardo De Santis, Elisa Patacchini, Valentina Noemi Madia, Francesco Saccoliti

J Enzyme Inhib Med Chem· August 2025

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Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Potent CFTR Corrector.
Elisa Romeo, Francesco Saccoliti, Riccardo Ocello, Angela Andonaia, Caterina Allegretta

J Med Chem· February 2025

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Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy.
Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi, Francesco Saccoliti

Pharmaceuticals (Basel)· December 2024

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Quinolinonyl Derivatives as Dual Inhibitors of the HIV-1 Integrase Catalytic Site and Integrase-RNA interactions.
Elisa Patacchini, Valentina Noemi Madia, Aurora Albano, Giuseppe Ruggieri, Antonella Messore, Francesco Saccoliti

ACS Med Chem Lett· September 2024

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New Thiazolidine-4-One Derivatives as SARS-CoV-2 Main Protease Inhibitors.
Antonella Messore, Paolo Malune, Elisa Patacchini, Valentina Noemi Madia, Davide Ialongo, Francesco Saccoliti

Pharmaceuticals (Basel)· May 2024

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Miconazole-like Scaffold is a Promising Lead for -Specific CYP51 Inhibitors.
Vandna Sharma, Valentina Noemi Madia, Valeria Tudino, Jennifer V Nguyen, Anjan Debnath, Francesco Saccoliti

J Med Chem· December 2023

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Inhibition of Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site.
Valentina Noemi Madia, Davide Ialongo, Elisa Patacchini, Cécile Exertier, Lorenzo Antonelli, Francesco Saccoliti

Molecules· January 2023

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Pyrrolyl and Indolyl α-γ-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII.
Davide Ialongo, Antonella Messore, Valentina Noemi Madia, Valeria Tudino, Alessio Nocentini, Francesco Saccoliti

Pharmaceuticals (Basel)· January 2023

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Effect of heparanase inhibitor on tissue factor overexpression in platelets and endothelial cells induced by anti-β2-GPI antibodies.
Antonella Capozzi, Gloria Riitano, Serena Recalchi, Valeria Manganelli, Roberta Costi, Francesco Saccoliti

J Thromb Haemost· September 2021

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Small-molecule Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H Function: Challenges and Recent Developments.
Valentina Noemi Madia, Antonella Messore, Alessandro De Leo, Valeria Tudino, Ivano Pindinello, Francesco Saccoliti

Curr Med Chem· September 2021

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Tegaserod for the Treatment of Irritable Bowel Syndrome.
Valentina Noemi Madia, Antonella Messore, Francesco Saccoliti, Valeria Tudino, Alessandro De Leo

Antiinflamm Antiallergy Agents Med Chem· July 2021

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Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase.
Antonella Messore, Angela Corona, Valentina Noemi Madia, Francesco Saccoliti, Valeria Tudino

J Med Chem· June 2021

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Investigation of (Nees) Engl. Oil and Its Main Components for Antiviral Activity.
Valentina Noemi Madia, Marta De Angelis, Daniela De Vita, Antonella Messore, Alessandro De Leo, Francesco Saccoliti

Pharmaceuticals (Basel)· March 2021

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Analytical Characterization of an Inulin-Type Fructooligosaccharide from Root-Tubers of L.
Valentina Noemi Madia, Daniela De Vita, Antonella Messore, Chiara Toniolo, Valeria Tudino, Francesco Saccoliti

Pharmaceuticals (Basel)· March 2021

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Design, Synthesis and Biological Evaluation of New Pyrimidine Derivatives as Anticancer Agents.
Valentina Noemi Madia, Alice Nicolai, Antonella Messore, Alessandro De Leo, Davide Ialongo, Francesco Saccoliti

Molecules· February 2021

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Recent Advancement in the Search of Innovative Antiprotozoal Agents Targeting Trypanothione Metabolism.
Francesco Saccoliti, Roberto Di Santo, Roberta Costi

ChemMedChem· December 2020

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Comparison of different methods for the extraction of cannabinoids from cannabis.
Daniela De Vita, Valentina Noemi Madia, Valeria Tudino, Francesco Saccoliti, Alessandro De Leo

Nat Prod Res· October 2020

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Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase.
Antonella Messore, Angela Corona, Valentina Noemi Madia, Francesco Saccoliti, Valeria Tudino

ACS Med Chem Lett· May 2020

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Discovery of a pyrimidine compound endowed with antitumor activity.
Ludovica Taglieri, Francesco Saccoliti, Alice Nicolai, Giovanna Peruzzi, Valentina Noemi Madia

Invest New Drugs· February 2020

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Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism.
Gianni Colotti, Francesco Saccoliti, Marina Gramiccia, Trentina Di Muccio, Jay Prakash

Amino Acids· February 2020

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Inhibition of Polycomb Repressive Complex 2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings.
Veronica Ruta, Chiara Longo, Alessandra Boccaccini, Valentina Noemi Madia, Francesco Saccoliti

BMC Plant Biol· October 2019

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Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.
Francesco Saccoliti, Valentina Noemi Madia, Valeria Tudino, Alessandro De Leo, Luca Pescatori

J Med Chem· February 2019

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In Vitro Antiviral Activity of New Oxazoline Derivatives as Potent Poliovirus Inhibitors.
Valentina Noemi Madia, Antonella Messore, Luca Pescatori, Francesco Saccoliti, Valeria Tudino

J Med Chem· January 2019

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