Publications by authors named "Franco Chimenti"

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Synthesis and biological evaluation of novel 2,4-disubstituted-1,3-thiazoles as anti-Candida spp. agents.
Franco Chimenti, Bruna Bizzarri, Adriana Bolasco, Daniela Secci, Paola Chimenti

Eur J Med Chem· January 2011

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Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.
Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Arianna Granese

J Med Chem· September 2010

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Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.
Franco Chimenti, Adriana Bolasco, Daniela Secci, Paola Chimenti, Arianna Granese

Bioorg Med Chem· August 2010

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Synthesis, selective anti-Helicobacter pylori activity, and cytotoxicity of novel N-substituted-2-oxo-2H-1-benzopyran-3-carboxamides.
Franco Chimenti, Bruna Bizzarri, Adriana Bolasco, Daniela Secci, Paola Chimenti

Bioorg Med Chem Lett· August 2010

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Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.
Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Arianna Granese

Bioorg Med Chem· July 2010

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Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.
Franco Chimenti, Simone Carradori, Daniela Secci, Adriana Bolasco, Bruna Bizzarri, Paola Chimenti

Eur J Med Chem· February 2010

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A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.
Franco Chimenti, Rossella Fioravanti, Adriana Bolasco, Paola Chimenti, Daniela Secci

Bioorg Med Chem· February 2010

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Synthesis and evaluation of 4-acyl-2-thiazolylhydrazone derivatives for anti-Toxoplasma efficacy in vitro.
Franco Chimenti, Bruna Bizzarri, Adriana Bolasco, Daniela Secci, Paola Chimenti

J Med Chem· August 2009

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Chalcones: a valid scaffold for monoamine oxidases inhibitors.
Franco Chimenti, Rossella Fioravanti, Adriana Bolasco, Paola Chimenti, Daniela Secci

J Med Chem· May 2009

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Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins.
Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Bruna Bizzarri

J Med Chem· April 2009

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A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone.
Franco Chimenti, Bruna Bizzarri, Elias Maccioni, Daniela Secci, Adriana Bolasco, Paola Chimenti

J Med Chem· January 2009

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Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.
Franco Chimenti, Rossella Fioravanti, Adriana Bolasco, Fedele Manna, Paola Chimenti

Eur J Med Chem· October 2008

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Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.
Franco Chimenti, Elias Maccioni, Daniela Secci, Adriana Bolasco, Paola Chimenti

J Med Chem· August 2008

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Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp.
Franco Chimenti, Bruna Bizzarri, Elias Maccioni, Daniela Secci, Adriana Bolasco, Paola Chimenti

Bioorg Med Chem Lett· August 2007

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A novel class of selective anti-Helicobacter pylori agents 2-oxo-2H-chromene-3-carboxamide derivatives.
Franco Chimenti, Bruna Bizzarri, Adriana Bolasco, Daniela Secci, Paola Chimenti

Bioorg Med Chem Lett· June 2007

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Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives.
Franco Chimenti, Elias Maccioni, Daniela Secci, Adriana Bolasco, Paola Chimenti

J Med Chem· February 2007

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Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5-diaryl pyrazole inhibitors.
Franco Chimenti, Rossella Fioravanti, Adriana Bolasco, Fedele Manna, Paola Chimenti

J Med Chem· February 2007

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Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors.
Franco Chimenti, Adriana Bolasco, Fedele Manna, Daniela Secci, Paola Chimenti

Curr Med Chem· August 2006

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Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of N,N'-bis[2-oxo-2H-benzopyran]-3-carboxamides.
Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Arianna Granese

Bioorg Med Chem Lett· August 2006

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Quercetin as the active principle of Hypericum hircinum exerts a selective inhibitory activity against MAO-A: extraction, biological analysis, and computational study.
Franco Chimenti, Filippo Cottiglia, Leonardo Bonsignore, Laura Casu, Mariano Casu, Paola Chimenti

J Nat Prod· June 2006

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Synthesis and molecular modelling of novel substituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase-A inhibitors.
Franco Chimenti, Adriana Bolasco, Fedele Manna, Daniela Secci, Paola Chimenti

Chem Biol Drug Des· March 2006

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Synthesis and in vitro selective anti-Helicobacter pylori activity of N-substituted-2-oxo-2H-1-benzopyran-3-carboxamides.
Franco Chimenti, Bruna Bizzarri, Adriana Bolasco, Daniela Secci, Paola Chimenti

Eur J Med Chem· February 2006

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Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.
Franco Chimenti, Elias Maccioni, Daniela Secci, Adriana Bolasco, Paola Chimenti

J Med Chem· November 2005

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Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein.
Fedele Manna, Franco Chimenti, Rossella Fioravanti, Adriana Bolasco, Daniela Secci, Paola Chimenti

Bioorg Med Chem Lett· October 2005

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Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study.
Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Arianna Granese

Bioorg Med Chem Lett· July 2004

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