Publications by authors named "Francois Roman"

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Effectiveness of the RTS,S/AS01 malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi.
Latif Ndeketa, Valérie Haine, Muriel Debois, Kwaku Poku Asante, Prince Darko Agyapong, François Roman

Lancet Glob Health· January 2026

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Safety of RTS,S/AS01 malaria vaccine up to 1 year after the third dose in Ghana, Kenya, and Malawi (EPI-MAL-003): a phase 4 cohort event monitoring study.
Valérie Haine, Martina Oneko, Muriel Debois, Latif Ndeketa, Prince Darko Agyapong, François Roman

Lancet Glob Health· June 2025

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Incidence rates of malaria, meningitis, and mortality in children younger than 5 years: a prospective cohort study in Ghana and Kenya before the roll-out of the RTS,S/AS01 malaria vaccine from 2016 to 2022.
Kwaku Poku Asante, Marie-Cécile Bozonnat, Miloje Savic, Seth Owusu-Agyei, Seyram Kaali, François Roman

Lancet Glob Health· May 2025

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A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective, and anti-inflammatory properties following status epilepticus in mice.
Lotfi Ferhat, Rabia Soussi, Maxime Masse, Grigorios Kyriatzis, Stéphane Girard, François Roman

Elife· March 2025

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Genotypic analysis of RTS,S/AS01 malaria vaccine efficacy against parasite infection as a function of dosage regimen and baseline malaria infection status in children aged 5-17 months in Ghana and Kenya: a longitudinal phase 2b randomised controlled trial.
Michal Juraska, Angela M Early, Li Li, Stephen F Schaffner, Marc Lievens, François Roman

Lancet Infect Dis· September 2024

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Could Less Be More? Accounting for Fractional-Dose Regimens and Different Number of Vaccine Doses When Measuring the Impact of the RTS,S/AS01E Malaria Vaccine.
Nelli Westercamp, Lawrence Osei-Tutu, Lode Schuerman, Simon K Kariuki, Anne Bollaerts, François Roman

J Infect Dis· August 2024

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Adjuvant system AS01: from mode of action to effective vaccines.
François Roman, Wivine Burny, Maria Angeles Ceregido, Béatrice Laupèze, Stéphane T Temmerman

Expert Rev Vaccines· August 2024

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Photobiomodulation Therapy: A Novel Therapeutic Approach to Alzheimer's Disease Made Possible by the Evidence of a Brain-Gut Interconnection.
Guillaume Blivet, François J Roman, Benjamin Lelouvier, Céline Ribière, Jacques Touchon

J Integr Neurosci· April 2024

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Translation from Preclinical Research to Clinical Trials: Brain-Gut Photobiomodulation Therapy for Alzheimer's Disease.
Guillaume Blivet, François J Roman, Julien Delrieu, Jacques Touchon

J Integr Neurosci· March 2024

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Incidence of Cytomegalovirus Primary and Secondary Infection in Adolescent Girls: Results From a Prospective Study.
Robert Paris, Dan Apter, Suresh Boppana, Maria D'Aloia, Nathalie De Schrevel, Francois Roman

J Infect Dis· November 2023

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Baseline malaria infection status and RTS,S/AS01E malaria vaccine efficacy.
Michal Juraska, Angela M Early, Li Li, Stephen F Schaffner, Marc Lievens, François Roman

medRxiv· November 2023

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Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial.
Joon Young Song, Won Suk Choi, Jung Yeon Heo, Eun Jin Kim, Jin Soo Lee, François Roman

EClinicalMedicine· October 2023

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Restorative effects of probiotics on memory impairment in sleep-deprived mice.
Síle M Griffin, Markus J Lehtinen, Johann Meunier, Laura Ceolin, Francois J Roman

Nutr Neurosci· March 2023

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The Helico Maze Detects Early Impairment of Reference Memory at Three Months of Age in the 5XFAD Mouse Model of Alzheimer's Disease.
Martine Migliorati, Christine Manrique, Melinda Rahrah, Guy Escoffier, Abdessadek El Ahmadi, François S Roman

J Alzheimers Dis· November 2022

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Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities.
Nathalie Charland, Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Annie Séguin, François Roman

NPJ Vaccines· November 2022

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Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19.
Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Nathalie Charland, Aurélien Lorin, François Roman

Nat Commun· November 2022

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Efficacy of RTS,S/AS01 malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5-17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial.
Aaron M Samuels, Daniel Ansong, Simon K Kariuki, Samuel Adjei, Anne Bollaerts, François Roman

Lancet Infect Dis· September 2022

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Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial.
Joon Young Song, Won Suk Choi, Jung Yeon Heo, Jin Soo Lee, Dong Sik Jung, François Roman

EClinicalMedicine· September 2022

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Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine.
Karen J Hager, Gonzalo Pérez Marc, Philipe Gobeil, Ricardo S Diaz, Gretchen Heizer, François Roman

N Engl J Med· June 2022

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Assessing the safety, impact and effectiveness of RTS,S/AS01 malaria vaccine following its introduction in three sub-Saharan African countries: methodological approaches and study set-up.
Nicolas Praet, Kwaku Poku Asante, Marie-Cecile Bozonnat, Elaine Jacqueline Akité, Patrick Odum Ansah, Francois Roman

Malar J· April 2022

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The Helico Maze allows testing of early learning and subcategories of long-term memory in mice.
Guy Escoffier, Martine Migliorati, Melinda Rahrah, Charles S M Roman, Michel Khrestchatisky, François S Roman

Behav Brain Res· May 2021

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Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries.
RTS,S Epidemiology EPI-MAL-005 Study Group The RTS,S Epidemiology EPI-MAL-005 Study Group Is Composed Of Per Alphabetical Order, Elisha Adeniji, Kwaku Poku Asante, Owusu Boahen, Guillaume Compaoré, François Roman

Am J Trop Med Hyg· November 2020

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Commentary in reply to a publication on Plasmodium falciparum pre-erythrocytic stage vaccine development.
François P Roman, Margherita Coccia, Lode Schuerman

Malar J· July 2020

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Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in adults in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial.
Milagritos D Tapia, Samba O Sow, Birahim P Ndiaye, Khardiata D Mbaye, Aliou Thiongane, François Roman

Lancet Infect Dis· June 2020

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Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in children in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial.
Milagritos D Tapia, Samba O Sow, Khardiata D Mbaye, Aliou Thiongane, Birahim P Ndiaye, François Roman

Lancet Infect Dis· June 2020

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