Publications by authors named "Frank Erdmann"

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Probing class I histone deacetylases (HDAC) with proteolysis targeting chimera (PROTAC) for the development of highly potent and selective degraders.
Hany S Ibrahim, Menglu Guo, Sebatian Hilscher, Frank Erdmann, Matthias Schmidt

Bioorg Chem· December 2024

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T14diLys/DOPE Liposomes: An Innovative Option for siRNA-Based Gene Knockdown?
Sophie Meinhard, Frank Erdmann, Henrike Lucas, Maria Krabbes, Stephanie Krüger

Pharmaceutics· December 2024

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Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase.
Abdallah M Alfayomy, Ramy Ashry, Anita G Kansy, Anne-Christin Sarnow, Frank Erdmann

Eur J Med Chem· March 2024

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Synthesis and in vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides.
Markus Lang, Uday S Ganapathy, Lea Mann, Rüdiger W Seidel, Richard Goddard, Frank Erdmann

ChemMedChem· March 2024

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A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer.
Sandra Kendzia, Susanne Franke, Tarek Kröhler, Nicole Golob-Schwarzl, Caroline Schweiger, Frank Erdmann

Mol Cancer· May 2023

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Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties.
Ping Sun, Jing Wang, Khadija S Khan, Weiqin Yang, Billy Wai-Lung Ng, Frank Erdmann

J Med Chem· December 2022

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Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.
Salma Darwish, Ehab Ghazy, Tino Heimburg, Daniel Herp, Patrik Zeyen, Frank Erdmann

Int J Mol Sci· July 2022

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Investigating 3R In Vivo Approaches for Bio-Distribution and Efficacy Evaluation of Nucleic Acid Nanocarriers: Studies on Peptide-Mimicking Ionizable Lipid.
Julia Giselbrecht, Shashank Reddy Pinnapireddy, Fatih Alioglu, Haider Sami, Daniel Sedding, Frank Erdmann

Small· May 2022

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Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Patrik Zeyen, Yanira Zeyn, Daniel Herp, Fereshteh Mahmoudi, Talha Z Yesiloglu, Frank Erdmann

Eur J Med Chem· April 2022

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Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis.
Ehab Ghazy, Tino Heimburg, Julien Lancelot, Patrik Zeyen, Karin Schmidtkunz, Frank Erdmann

Eur J Med Chem· December 2021

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Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
Hany S Ibrahim, Mohamed Abdelsalam, Yanira Zeyn, Matthes Zessin, Al-Hassan M Mustafa, Frank Erdmann

Int J Mol Sci· December 2021

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Different PEG-PLGA Matrices Influence In Vivo Optical/Photoacoustic Imaging Performance and Biodistribution of NIR-Emitting π-Conjugated Polymer Contrast Agents.
Paul Robert Neumann, Frank Erdmann, Joost Holthof, Gabriela Hädrich, Mark Green

Adv Healthc Mater· February 2021

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Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
Ehab Ghazy, Patrik Zeyen, Daniel Herp, Martin Hügle, Karin Schmidtkunz, Frank Erdmann

Eur J Med Chem· August 2020

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Study on the potential mechanism of anti-inflammatory activity of covalently immobilized hyaluronan and heparin.
Hala AlKhoury, Adrian Hautmann, Frank Erdmann, Guoying Zhou, Sanja Stojanović

J Biomed Mater Res A· May 2020

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Studies on the Mechanisms of Anti-Inflammatory Activity of Heparin- and Hyaluronan-Containing Multilayer Coatings-Targeting NF-κB Signalling Pathway.
Hala Alkhoury, Adrian Hautmann, Bodo Fuhrmann, Frank Syrowatka, Frank Erdmann

Int J Mol Sci· May 2020

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Contact-Triggered Lipofection from Multilayer Films Designed as Surfaces for in Situ Transfection Strategies in Tissue Engineering.
Catharina Husteden, Falko Doberenz, Nathalie Goergen, Shashank Reddy Pinnapireddy, Christopher Janich, Frank Erdmann

ACS Appl Mater Interfaces· February 2020

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Nucleic acid carrier composed of a branched fatty acid lysine conjugate-Interaction studies with blood components.
Julia Giselbrecht, Sophia Wiedemann, Shashank Reddy Pinnapireddy, Nathalie Goergen, Harald Loppnow, Frank Erdmann

Colloids Surf B Biointerfaces· December 2019

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A triple chain polycationic peptide-mimicking amphiphile - efficient DNA-transfer without co-lipids.
Shashank Reddy Pinnapireddy, Julia Giselbrecht, Boris Strehlow, Christopher Janich, Catharina Husteden, Frank Erdmann

Biomater Sci· December 2019

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Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphofia foliosa Hochst.
Ruth Feilcke, Georgette Arnouk, Boingotlo Raphane, Khumoekae Richard, Ian Tietjen, Frank Erdmann

J Pharm Biomed Anal· September 2019

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Antistaphylococcal evaluation of indole-naphthalene hybrid analogs.
Kerolos Ashraf, Kaveh Yasrebi, Emmanuel Tola Adeniyi, Tobias Hertlein, Knut Ohlsen, Frank Erdmann

Drug Des Devel Ther· June 2019

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Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1.
Abdulkarim Najjar, Charlott Platzer, Anton Luft, Chris Alexander Aßmann, Nehal H Elghazawy, Frank Erdmann

Eur J Med Chem· January 2019

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Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.
Theresa Bayer, Alokta Chakrabarti, Julien Lancelot, Tajith B Shaik, Kristin Hausmann, Frank Erdmann

ChemMedChem· August 2018

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Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II.
Charlott Platzer, Abdulkarim Najjar, Alexander Rohe, Frank Erdmann, Wolfgang Sippl

Bioorg Med Chem· August 2018

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Screening for Selective Protein Inhibitors by Using the IANUS Peptide Array.
Frank Erdmann, Erik Prell, Günther Jahreis, Gunter Fischer, Miroslav Malešević

Chembiochem· April 2018

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Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity.
Tino Heimburg, Fiona R Kolbinger, Patrik Zeyen, Ehab Ghazy, Daniel Herp, Frank Erdmann

J Med Chem· December 2017

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