Publications by authors named "Frank Luh"

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A method to validate viral copy-number assay involving a hybrid amplicon and duplex droplet digital PCR.
Raymond Wu, Frank Luh, Soo-Mi Kweon, Yun Yen

Mol Ther Methods Clin Dev· June 2025

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Exosomes: a review of biologic function, diagnostic and targeted therapy applications, and clinical trials.
Yi-Fan Chen, Frank Luh, Yuan-Soon Ho, Yun Yen

J Biomed Sci· July 2024

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Impact of N221S missense mutation in human ribonucleotide reductase small subunit b on mitochondrial DNA depletion syndrome.
Leila Su, Xin Wang, Jianghai Wang, Frank Luh, Yun Yen

Sci Rep· November 2023

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A Phase II Clinical Trial on the Combination Therapy of PHY906 Plus Capecitabine in Hepatocellular Carcinoma.
Chun A Changou, Her-Shyong Shiah, Li-Tzong Chen, Servina Liu, Frank Luh

Oncologist· March 2021

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Kinesin family member 11 is a potential therapeutic target and is suppressed by microRNA-30a in breast cancer.
Benfang Wang, Jianjiang Yu, Zhenjiang Sun, Frank Luh, Dandan Lin

Mol Carcinog· August 2020

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Cybersecurity in Science and Medicine: Threats and Challenges.
Frank Luh, Yun Yen

Trends Biotechnol· August 2020

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Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway.
Grace Wakabayashi, Yu-Ching Lee, Frank Luh, Chun-Nan Kuo, Wei-Chiao Chang

J Biomed Sci· December 2019

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Correction to: Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway.
Grace Wakabayashi, Yu-Ching Lee, Frank Luh, Chun-Nan Kuo, Wei-Chiao Chang

J Biomed Sci· December 2019

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A homozygous variant in RRM2B is associated with severe metabolic acidosis and early neonatal death.
Brent A Penque, Leila Su, Jianghai Wang, Weizhen Ji, Allen Bale, Frank Luh

Eur J Med Genet· November 2019

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LKB1 deficiency promotes proliferation and invasion of glioblastoma through activation of mTOR and focal adhesion kinase signaling pathways.
Keqiang Zhang, Jinghan Wang, Jinhui Wang, Frank Luh, Xiyong Liu

Am J Cancer Res· August 2019

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Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer.
Huajun Lu, Chaoqun Wang, Lijun Xue, Qi Zhang, Frank Luh

J Oncol· April 2019

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Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
Stephanie L Schmit, Christopher K Edlund, Fredrick R Schumacher, Jian Gong, Tabitha A Harrison, Frank Luh

J Natl Cancer Inst· February 2019

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Overexpression of the ASPM gene is associated with aggressiveness and poor outcome in bladder cancer.
Zhenglin Xu, Qi Zhang, Frank Luh, Baiye Jin, Xiyong Liu

Oncol Lett· February 2019

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Ribonucleotide reductase subunit M2B deficiency leads to mitochondrial permeability transition pore opening and is associated with aggressive clinicopathologic manifestations of breast cancer.
Lijun Xue, Xiyong Liu, Qinchuan Wang, Charlie Q Liu, Yunru Chen, Frank Luh

Am J Transl Res· November 2018

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FDA guidance for next generation sequencing-based testing: balancing regulation and innovation in precision medicine.
Frank Luh, Yun Yen

NPJ Genom Med· October 2018

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Benefits and Harms of the Centers for Medicare & Medicaid Services Ruling on Next-Generation Sequencing.
Frank Luh, Yun Yen

JAMA Oncol· September 2018

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Web-Based Platform vs Genetic Counselors in Educating Patients About Carrier Results From Exome Sequencing.
Yun Yen, Frank Luh

JAMA Intern Med· July 2018

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Overexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor Prognosis.
Guosong Shen, Pingya He, Yingying Mao, Peipei Li, Frank Luh

J Breast Cancer· June 2017

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Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers.
Jiefeng Ding, Mei-Ling Kuo, Leila Su, Lijun Xue, Frank Luh

Carcinogenesis· May 2017

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Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker.
Lahong Zhang, Zhaojun Chen, Dan Xue, Qi Zhang, Xiyong Liu, Frank Luh

Oncol Rep· November 2016

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Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis.
Chien-Ju Lin, Yi-Ling Lin, Frank Luh, Yun Yen, Ruei-Ming Chen

Oncotarget· July 2016

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Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.
Sheng-Huei Yang, Hung-Yun Lin, Chun A Changou, Chun-Han Chen, Yun-Ru Liu, Frank Luh

Oncotarget· January 2016

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Intrahepatic cholangiocarcinoma and hepatitis: case study and literature review.
Frank Luh, Andrew Kuei, Patricia Fann, Peiguo Chu, Yun Yen

Anticancer Res· August 2009

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The induction of growth arrest DNA damage-inducible gene 45 beta in human hepatoma cell lines by S-adenosylmethionine.
Weihua Qiu, Bingsen Zhou, Peiguo G Chu, Frank Luh, Yun Yen

Am J Pathol· July 2007

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The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.
Bingsen Zhou, Xiyong Liu, Xueli Mo, Lijun Xue, Dana Darwish, Frank Luh

Cancer Res· October 2003

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