Publications by authors named "Frank Maley"

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F
Functional identity of the active sites of crustacean and viral thymidylate synthases.
Aldo A Arvizu-Flores, Emmanuel Aispuro-Hernandez, Karina D Garcia-Orozco, Alejandro Varela-Romero, Elisa Valenzuela-Soto, Frank Maley

Comp Biochem Physiol C Toxicol Pharmacol· September 2009

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Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: calorimetric and crystallographic analysis of the K48Q mutant.
Aldo A Arvizu-Flores, Rocio Sugich-Miranda, Rodrigo Arreola, Karina D Garcia-Orozco, Enrique F Velazquez-Contreras, Frank Maley

Int J Biochem Cell Biol· October 2008

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Role of Y94 in proton and hydride transfers catalyzed by thymidylate synthase.
Baoyu Hong, Frank Maley, Amnon Kohen

Biochemistry· December 2007

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Chloroviruses encode a bifunctional dCMP-dCTP deaminase that produces two key intermediates in dTTP formation.
Yuanzheng Zhang, Frank Maley, Gladys F Maley, Garry Duncan, David D Dunigan

J Virol· July 2007

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Significance of mutations on the structural perturbation of thymidylate synthase: implications for their involvement in subunit exchange.
Ruth L Saxl, Gladys F Maley, Charles R Hauer, Robert Maccoll, Liming Changchien, Frank Maley

Protein Sci· July 2007

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Structure of the Y94F mutant of Escherichia coli thymidylate synthase.
Sue A Roberts, David C Hyatt, Jerry E Honts, Liming Changchien, Gladys F Maley, Frank Maley

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2006

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Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity.
Rogerio R Sotelo-Mundo, Liming Changchien, Frank Maley, William R Montfort

J Biochem Mol Toxicol· June 2006

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Hydride transfer versus hydrogen radical transfer in thymidylate synthase.
Baoyu Hong, Majd Haddad, Frank Maley, Jan H Jensen, Amnon Kohen

J Am Chem Soc· May 2006

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Binding and repression of translation of the cognate mRNA by Trichinella spiralis thymidylate synthase differ from the corresponding interactions of the human enzyme.
Joanna Cieśla, Elzbieta Jagielska, Tomasz Skopiński, Magdalena D Abrowska, Frank Maley

Biochem J· September 2005

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Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.
Gina M Capiaux, Tulin Budak-Alpdogan, Onder Alpdogan, William Bornmann, Naoko Takebe, Frank Maley

Cancer Gene Ther· December 2004

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Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase.
Rami Almog, Frank Maley, Gladys F Maley, Robert Maccoll, Patrick Van Roey

Biochemistry· November 2004

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A trojan horse approach for silencing thymidylate synthase.
Deborah K West, Donald C Porter, Ruth L Saxl, Frank Maley

Biochemistry· July 2004

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Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase.
Xiukun Lin, Jun Liu, Frank Maley, Edward Chu

Nucleic Acids Res· August 2003

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Human cytomegalovirus requires cellular deoxycytidylate deaminase for replication in quiescent cells.
Giorgio Gribaudo, Ludovica Riera, Patrizia Caposio, Frank Maley, Santo Landolfo

J Gen Virol· June 2003

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Modification of Escherichia coli thymidylate synthase at tyrosine-94 by 5-imidazolylpropynyl-2'-deoxyuridine 5'-monophosphate.
Ruth L Saxl, James Reston, Zhe Nie, Thomas I Kalman, Frank Maley

Biochemistry· April 2003

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Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.
Gina M Capiaux, Tulin Budak-Alpdogan, Naoko Takebe, Philipp Mayer-Kuckuk, Debabrata Banerjee, Frank Maley

Hum Gene Ther· March 2003

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Mechanistic characterization of Toxoplasma gondii thymidylate synthase (TS-DHFR)-dihydrofolate reductase. Evidence for a TS intermediate and TS half-sites reactivity.
Eric F Johnson, Wolfgang Hinz, Chloe E Atreya, Frank Maley, Karen S Anderson

J Biol Chem· November 2002

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