Publications by authors named "Frank Slack"

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MicroRNA-21 is a potential therapeutic agent targeting and mitigating high-fat-diet-induced liver disease and cancer.
Urmila Jagtap, Anan Quan, Yuho Ono, Jonathan D Lee, Alice Rodrigues, Frank J Slack

Mol Ther Nucleic Acids· December 2025

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Age-dependent transcriptomic effects of morphine in the frontal cortex of female mice.
Jarvis Savage, Anupama Rai, Jonathan D Lee, Jane Banahan, Kristina Dujic, Frank J Slack

Neuropharmacology· December 2025

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tRNA modifications are required for stress granule formation and melanoma metastasis.
Riley O Hughes, Hannah J Davis, Leona A Nease, Paul Zumbo, Mauro Danielli, Frank J Slack

bioRxiv· August 2025

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EGFR-induced lncRNA promotes drug resistance in non-small cell lung cancer via phospho-TRIM28-mediated DNA damage repair.
Tanvi Saxena, Anan Quan, Erica Chan, Nina Kozlova, Latika Matai, Frank J Slack

Proc Natl Acad Sci U S A· March 2025

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Host microRNA-31-5p represses oncogenic herpesvirus lytic reactivation by restricting the RNA-binding protein KHDRBS3-mediated viral gene expression.
Soo Mi Lee, Christopher L Avalos, Christos Miliotis, Hanna M Doh, Erica Chan, Frank J Slack

bioRxiv· January 2025

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Extracellular vesicle-encapsulated miR-30c-5p reduces aging-related liver fibrosis.
Alice C Rodrigues, Yujing J Heng, Frank J Slack

Aging Cell· December 2024

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Development of bioconjugate-based delivery systems for nucleic acids.
Aniket Wahane, Vishal Kasina, Mounika Pathuri, Ciara Marro-Wilson, Anisha Gupta, Frank J Slack

RNA· December 2024

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miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice.
Urmila Jagtap, Anan Quan, Yuho Ono, Jonathan Lee, Kylie A Shen, Frank J Slack

bioRxiv· October 2024

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sChemNET: a deep learning framework for predicting small molecules targeting microRNA function.
Diego Galeano, Imrat, Jeffrey Haltom, Chaylen Andolino, Aliza Yousey, Frank J Slack

Nat Commun· October 2024

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Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models.
Eric Struth, Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn Cramer, Frank J Slack

Sci Rep· September 2024

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Sensitive Multiplexed MicroRNA Spatial Profiling and Data Classification Framework Applied to Murine Breast Tumors.
Omar N Mohd, Yujing J Heng, Lin Wang, Abhishek Thavamani, Erica S Massicott, Frank J Slack

Anal Chem· August 2024

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Enhancing RNA inhibitory activity using clamp-G-modified nucleobases.
Sai Pallavi Pradeep, Vikas Kumar, Shipra Malik, Frank J Slack, Anisha Gupta

Cell Rep Phys Sci· August 2024

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Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models.
Eric Struth, Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn Cramer, Frank J Slack

bioRxiv· July 2024

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Determinants of gastric cancer immune escape identified from non-coding immune-landscape quantitative trait loci.
Christos Miliotis, Yuling Ma, Xanthi-Lida Katopodi, Dimitra Karagkouni, Eleni Kanata, Frank J Slack

Nat Commun· May 2024

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Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy.
Haisheng Yu, Jing Liu, Xia Bu, Zhiqiang Ma, Yingmeng Yao, Frank J Slack

Cell Chem Biol· April 2024

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Epstein-Barr virus-encoded EBNA2 downregulates ICOSL by inducing miR-24 in B-cell lymphoma.
Martina Leopizzi, Lucia Mundo, Elena Messina, Federica Campolo, Stefano Lazzi, Frank Slack

Blood· February 2024

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Cognition-associated long noncoding RNAs are dysregulated upon severe COVID-19.
Jonathan D Lee, Isaac H Solomon, Frank J Slack, Maria Mavrikaki

Front Immunol· February 2024

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Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.
Jonathan D Lee, Bridget L Menasche, Maria Mavrikaki, Madison M Uyemura, Su Min Hong, Frank J Slack

Cell Rep· December 2023

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Lipid kinase PIP5K1A regulates let-7 microRNA biogenesis through interacting with nuclear export protein XPO5.
Chun Li, Bohyung Yoon, Giovanni Stefani, Frank J Slack

Nucleic Acids Res· October 2023

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Head-to-head comparison of and efficacy of pHLIP-conjugated anti-seed gamma peptide nucleic acids.
Karishma Dhuri, Tibo Duran, Bodhisattwa Chaudhuri, Frank J Slack, Ajit Vikram

Cell Rep Phys Sci· October 2023

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Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.
Jonathan D Lee, Bridget L Menasche, Maria Mavrikaki, Madison M Uyemura, Su Min Hong, Frank J Slack

bioRxiv· September 2023

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PanomiR: a systems biology framework for analysis of multi-pathway targeting by miRNAs.
Pourya Naderi Yeganeh, Yue Y Teo, Dimitra Karagkouni, Yered Pita-Juárez, Sarah L Morgan, Frank J Slack

Brief Bioinform· September 2023

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Next-generation poly-L-histidine formulations for miRNA mimic delivery.
Vishal Kasina, Aniket Wahane, Chung-Hao Liu, Lin Yang, Mu-Ping Nieh, Frank J Slack

Mol Ther Methods Clin Dev· June 2023

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MicroRNAs in Age-Related Proteostasis and Stress Responses.
Latika Matai, Frank J Slack

Noncoding RNA· April 2023

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Severe COVID-19 is associated with molecular signatures of aging in the human brain.
Maria Mavrikaki, Jonathan D Lee, Isaac H Solomon, Frank J Slack

Nat Aging· December 2022

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