Publications by authors named "Fraser Conrad"

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Single Tri-Epitopic Antibodies (TeAbs) to Botulinum Neurotoxin Serotypes B, E, and F Recapitulate the Full Potency of a Combination of Three Monoclonal Antibodies in Toxin Neutralization.
Jianlong Lou, Wei Hua Wen, Fraser Conrad, Christina C Tam, Consuelo Garcia-Rodriguez

Toxins (Basel)· June 2025

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Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F.
Yongfeng Fan, Zhengda Sun, Fraser Conrad, Weihua Wen, Lequn Zhao

PLoS One· August 2023

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A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice.
Yongfeng Fan, Jianlong Lou, Christina C Tam, Weihua Wen, Fraser Conrad

Toxins (Basel)· April 2023

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A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D.
Consuelo Garcia-Rodriguez, Shude Yan, Isin N Geren, Kristeene A Knopp, Jianbo Dong, Fraser Conrad

Toxins (Basel)· September 2021

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The Novel Clostridial Neurotoxin Produced by Strain IBCA10-7060 Is Immunologically Equivalent to BoNT/HA.
Yongfeng Fan, Jason R Barash, Fraser Conrad, Jianlong Lou, Christina Tam

Toxins (Basel)· December 2019

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Safety and Pharmacokinetics of a Four Monoclonal Antibody Combination Against Botulinum C and D Neurotoxins.
Doris M Snow, Kathryn Riling, Angie Kimbler, Yero Espinoza, David Wong, Fraser Conrad

Antimicrob Agents Chemother· September 2019

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Integrin αvβ8-expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells.
Naoki Takasaka, Robert I Seed, Anthony Cormier, Andrew J Bondesson, Jianlong Lou, Fraser Conrad

JCI Insight· October 2018

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Antibody engineering to improve manufacturability.
Sujeewa D Wijesuriya, Elizabeth Pongo, Milan Tomic, Fangjiu Zhang, Consuelo Garcia-Rodriquez, Fraser Conrad

Protein Expr Purif· September 2018

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A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes.
Consuelo Garcia-Rodriguez, Ali Razai, Isin N Geren, Jianlong Lou, Fraser Conrad

Toxins (Basel)· March 2018

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A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A.
Jianlong Lou, Weihua Wen, Fraser Conrad, Qi Meng, Jianbo Dong

Toxins (Basel)· February 2018

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A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype F subtypes.
Yongfeng Fan, Consuelo Garcia-Rodriguez, Jianlong Lou, Weihua Wen, Fraser Conrad

PLoS One· September 2017

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Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity.
Yongfeng Fan, Isin N Geren, Jianbo Dong, Jianlong Lou, Weihua Wen, Fraser Conrad

PLoS One· May 2016

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Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H.
Yongfeng Fan, Jason R Barash, Jianlong Lou, Fraser Conrad, James D Marks

J Infect Dis· May 2016

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Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.
Yongfeng Fan, Jianbo Dong, Jianlong Lou, Weihua Wen, Fraser Conrad

Toxins (Basel)· August 2015

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Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies.
Yu Zhou, Anne-Laure Goenaga, Brian D Harms, Hao Zou, Jianlong Lou, Fraser Conrad

Mol Cancer Ther· July 2012

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Affinity maturation to improve human monoclonal antibody neutralization potency and breadth against hepatitis C virus.
Yong Wang, Zhen-Yong Keck, Anasuya Saha, Jinming Xia, Fraser Conrad

J Biol Chem· December 2011

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A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region.
Jianbo Dong, Aaron A Thompson, Yongfeng Fan, Jianlong Lou, Fraser Conrad

J Mol Biol· April 2010

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Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion.
Fraser Conrad, Xiaodong Zhu, Xin Zhang, Robert J Chalkley, Alma L Burlingame

J Mol Med (Berl)· May 2009

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Recombinant full-length human IgG1s targeting hormone-refractory prostate cancer.
Bin Liu, Fraser Conrad, Audrey Roth, Daryl C Drummond, Jeff P Simko

J Mol Med (Berl)· October 2007

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Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells.
Audrey Roth, Daryl C Drummond, Fraser Conrad, Mark E Hayes, Dmitri B Kirpotin

Mol Cancer Ther· October 2007

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Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells.
Bin Liu, Fraser Conrad, Matthew R Cooperberg, Dmitri B Kirpotin, James D Marks

Cancer Res· January 2004

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