Publications by authors named "Frazer Lowe"

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Comparative study of the effects of cigarette smoke versus next-generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes.
Sindy Giebe, Melanie Brux, Anja Hofmann, Frazer Lowe, Damien Breheny

Pflugers Arch· July 2023

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An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure.
Karsta Luettich, Monita Sharma, Hasmik Yepiskoposyan, Damien Breheny, Frazer J Lowe

Front Toxicol· December 2021

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Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function.
Sindy Giebe, Anja Hofmann, Melanie Brux, Frazer Lowe, Damien Breheny

Redox Biol· November 2021

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Impact of cigarette versus electronic cigarette aerosol conditioned media on aortic endothelial cells in a microfluidic cardiovascular model.
Om Makwana, Gina A Smith, Hannah E Flockton, Gary P Watters, Frazer Lowe

Sci Rep· February 2021

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Statistical analysis plan for "A randomised, controlled study to evaluate the effects of switching from cigarette smoking to using a tobacco heating product on health effect indicators in healthy subjects".
Oscar M Camacho, Andrew Hedge, Frazer Lowe, Nik Newland, Nathan Gale

Contemp Clin Trials Commun· March 2020

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Evaluating the effects of switching from cigarette smoking to using a heated tobacco product on health effect indicators in healthy subjects: study protocol for a randomized controlled trial.
Nik Newland, Frazer John Lowe, Oscar Martin Camacho, Mike McEwan, Nathan Gale

Intern Emerg Med· September 2019

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Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase.
Tamer M Abdelghany, Raed S Ismail, Fatma A Mansoor, Joseph R Zweier, Frazer Lowe

Nitric Oxide· June 2018

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Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette.
James Murphy, Marianna Gaca, Frazer Lowe, Emmanuel Minet, Damien Breheny

Regul Toxicol Pharmacol· November 2017

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A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (Part 2): In vitro biological assessment and comparison with different tobacco-heating products.
Damien Breheny, Jason Adamson, David Azzopardi, Andrew Baxter, Emma Bishop, Frazer Lowe

Food Chem Toxicol· August 2017

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A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration.
Mark Taylor, Tomasz Jaunky, Katherine Hewitt, Damien Breheny, Frazer Lowe

Toxicol Lett· August 2017

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E-cigarette aerosols induce lower oxidative stress in vitro when compared to tobacco smoke.
Mark Taylor, Tony Carr, Oluwatobiloba Oke, Tomasz Jaunky, Damien Breheny, Frazer Lowe

Toxicol Mech Methods· July 2016

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Changes in levels of biomarkers of exposure and biological effect in a controlled study of smokers switched from conventional cigarettes to reduced-toxicant-prototype cigarettes.
Christopher J Shepperd, Nik Newland, Alison Eldridge, Linsey Haswell, Frazer Lowe

Regul Toxicol Pharmacol· July 2015

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A cross-sectional analysis of candidate biomarkers of biological effect in smokers, never-smokers and ex-smokers.
Linsey E Haswell, Ermioni Papadopoulou, Nik Newland, Christopher J Shepperd, Frazer J Lowe

Biomarkers· August 2014

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A novel autoantibody test for the detection of pre-neoplastic lung lesions.
Frazer J Lowe, Weike Shen, Jinchi Zu, Junfu Li, Hao Wang

Mol Cancer· April 2014

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Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective.
Frazer J Lowe, Karsta Luettich, Evan O Gregg

Biomarkers· May 2013

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A cross-sectional investigation of biomarkers of risk after a decade of smoking.
Gioacchino Calapai, Achille P Caputi, Carmen Mannucci, Evan O Gregg, Antonella Pieratti, Frazer Lowe

Inhal Toxicol· November 2009

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Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers.
Frazer J Lowe, Evan O Gregg, Michael McEwan

Clin Chem Lab Med· August 2009

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Cardiovascular biomarkers in groups of established smokers after a decade of smoking.
Gioacchino Calapai, Achille P Caputi, Carmen Mannucci, Giuseppina A Russo, Evan Gregg, Frazer Lowe

Basic Clin Pharmacol Toxicol· April 2009

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Smoking selectively accelerates carotid atherosclerosis in hypertensive patients.
Raffaele Izzo, Gianfranco Di Renzo, Nicola De Luca, Valentina Trimarco, Francesco Buono, Frazer Lowe

High Blood Press Cardiovasc Prev· October 2008

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