Publications by authors named "Fred Armbrust"

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HYTANE-Identified Latrophilin-3 Cleavage by Meprin β Leads to Loss of the Interaction Domains.
Fred Armbrust, Kira Bickenbach, Tomas Koudelka, Corentin Joos, Maximilian Keller

J Proteome Res· April 2025

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Targeted approach to determine the impact of cancer-associated protease variants.
Kira Bickenbach, Nele David, Tomas Koudelka, Corentin Joos, Franka Scharfenberg, Fred Armbrust

Sci Adv· February 2025

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A novel mouse model for N-terminal truncated Aβ2-x generation through meprin β overexpression in astrocytes.
Fred Armbrust, Kira Bickenbach, Hermann Altmeppen, Angelica Foggetti, Anne Winkelmann

Cell Mol Life Sci· March 2024

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Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis.
Cynthia Bülck, Elisabeth E L Nyström, Tomas Koudelka, Michael Mannbar-Frahm, Gerrit Andresen, Fred Armbrust

Sci Adv· March 2023

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MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties.
Ludwig Werny, Antonia Grogro, Kira Bickenbach, Cynthia Bülck, Fred Armbrust

FEBS J· January 2023

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The Swedish dilemma - the almost exclusive use of APPswe-based mouse models impedes adequate evaluation of alternative β-secretases.
Fred Armbrust, Kira Bickenbach, Liana Marengo, Claus Pietrzik, Christoph Becker-Pauly

Biochim Biophys Acta Mol Cell Res· March 2022

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Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.
Liana Marengo, Fred Armbrust, Caroline Schoenherr, Steffen E Storck, Ulrich Schmitt

Cell Mol Life Sci· March 2022

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Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R.
Antonin Gellrich, Franka Scharfenberg, Florian Peters, Martin Sammel, Ole Helm, Fred Armbrust

Front Mol Biosci· October 2021

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Phosphorylation of meprin β controls its cell surface abundance and subsequently diminishes ectodomain shedding.
Fred Armbrust, Kira Bickenbach, Tomas Koudelka, Andreas Tholey, Claus Pietrzik

FASEB J· July 2021

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Meprin β cleaves TREM2 and controls its phagocytic activity on macrophages.
Dennis Kristopher Berner, Luisa Wessolowski, Fred Armbrust, Janna Schneppenheim, Kai Schlepckow

FASEB J· May 2020

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Degranulation of human cytotoxic lymphocytes is a major source of proteolytically active soluble CD26/DPP4.
Marcus Lettau, Michelle Dietz, Sarah Vollmers, Fred Armbrust, Christian Peters

Cell Mol Life Sci· February 2020

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Regulation of the alternative β-secretase meprin β by ADAM-mediated shedding.
Franka Scharfenberg, Fred Armbrust, Liana Marengo, Claus Pietrzik, Christoph Becker-Pauly

Cell Mol Life Sci· August 2019

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Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes.
Florian Peters, Franka Scharfenberg, Cynthia Colmorgen, Fred Armbrust, Rielana Wichert

FASEB J· June 2019

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Mechanistic peculiarities of activation-induced mobilization of cytotoxic effector proteins in human T cells.
Marcus Lettau, Fred Armbrust, Katharina Dohmen, Lisann Drews, Tobias Poch

Int Immunol· April 2018

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