Publications by authors named "Fred D Ledley"

Claim this Profile
C
Contribution of revenue from drugs subject to price negotiation under the Inflation Reduction Act to the revenue, profit, and returns of pharmaceutical manufacturers.
Joseph Twomey, Leonhard Kersten, Edward W Zhou, Fred D Ledley

Drug Discov Today· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sustaining pharmaceutical innovation after the Inflation Reduction Act: trends in R&D spending, equity investment, and business development.
Henry Dao, Fred D Ledley

Drug Discov Today· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Modeling impact of inflation reduction act price negotiations on new drug pipeline considering differential contributions of large and small biopharmaceutical companies.
Gregory Vaughan, Roger Du, Fred D Ledley

Clin Trials· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Association between expedited review designations and the US or global burden of disease for drugs approved by the US Food and Drug Administration, 2010-2019: a cross-sectional analysis.
Matthew J Jackson, Gregory Vaughan, Fred D Ledley

BMJ Open· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spending on Phased Clinical Development of Approved Drugs by the US National Institutes of Health Compared With Industry.
Edward W Zhou, Matthew J Jackson, Fred D Ledley

JAMA Health Forum· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NIH funding for patents that contribute to market exclusivity of drugs approved 2010-2019 and the public interest protections of Bayh-Dole.
Fred D Ledley, Ekaterina Galkina Cleary

PLoS One· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparing the economic terms of biotechnology licenses from academic institutions with those between commercial firms.
Prateet Shah, Gregory Vaughan, Fred D Ledley

PLoS One· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparison of Research Spending on New Drug Approvals by the National Institutes of Health vs the Pharmaceutical Industry, 2010-2019.
Ekaterina Galkina Cleary, Matthew J Jackson, Edward W Zhou, Fred D Ledley

JAMA Health Forum· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparing long-term value creation after biotech and non-biotech IPOs, 1997-2016.
Ekaterina Galkina Cleary, Laura M McNamee, Skyler de Boer, Jeremy Holden, Liam Fitzgerald, Fred D Ledley

PLoS One· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NIH funding for vaccine readiness before the COVID-19 pandemic.
Anthony E Kiszewski, Ekaterina Galkina Cleary, Matthew J Jackson, Fred D Ledley

Vaccine· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Late-stage Product Development and Approvals by Biotechnology Companies After Initial Public Offering, 1997-2016.
Laura M McNamee, Ekaterina Galkina Cleary, Sunyi Zhang, Usama Salim, Fred D Ledley

Clin Ther· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NIH funding for research underlying new cancer therapies.
Ekaterina Galkina Cleary, Fred D Ledley

Lancet Oncol· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
We Don't Have to Lose STEM Students to Business.
Naomi L B Wernick, Fred D Ledley

J Microbiol Biol Educ· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Profitability of Large Pharmaceutical Companies Compared With Other Large Public Companies.
Fred D Ledley, Sarah Shonka McCoy, Gregory Vaughan, Ekaterina Galkina Cleary

JAMA· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Representation of Industry in Introductory Biology Textbooks: A Missed Opportunity to Advance STEM Learning.
Sharotka M Simon, Helen Meldrum, Eric Ndung'u, Fred D Ledley

CBE Life Sci Educ· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Methods Used to Assess Pharmaceutical Research and Development Costs.
Fred D Ledley

JAMA Intern Med· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Contribution of NIH funding to new drug approvals 2010-2016.
Ekaterina Galkina Cleary, Jennifer M Beierlein, Navleen Surjit Khanuja, Laura M McNamee, Fred D Ledley

Proc Natl Acad Sci U S A· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
As Technologies for Nucleotide Therapeutics Mature, Products Emerge.
Jennifer M Beierlein, Laura M McNamee, Fred D Ledley

Mol Ther Nucleic Acids· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Timelines of translational science: From technology initiation to FDA approval.
Laura M McNamee, Michael Jay Walsh, Fred D Ledley

PLoS One· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Modeling timelines for translational science in cancer; the impact of technological maturation.
Laura M McNamee, Fred D Ledley

PLoS One· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Landscape of Innovation for Cardiovascular Pharmaceuticals: From Basic Science to New Molecular Entities.
Jennifer M Beierlein, Laura M McNamee, Michael J Walsh, Kenneth I Kaitin, Joseph A DiMasi, Fred D Ledley

Clin Ther· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Patterns of Innovation in Alzheimer's Disease Drug Development: A Strategic Assessment Based on Technological Maturity.
Jennifer M Beierlein, Laura M McNamee, Michael J Walsh, Fred D Ledley

Clin Ther· August 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Positioning genomics in biology education: content mapping of undergraduate biology textbooks.
Naomi L B Wernick, Eric Ndung'u, Dominique Haughton, Fred D Ledley

J Microbiol Biol Educ· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Patterns of technological innovation in biotech.
Laura M McNamee, Fred D Ledley

Nat Biotechnol· October 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
VII. Informed consent.
Fred David Ledley

Hum Gene Ther· January 1993

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis