Publications by authors named "Fred Jacobson"

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CMC Regulatory Considerations for Antibody-Drug Conjugates.
Karoline Bechtold-Peters, Andrea Ruggiero, Nienke Vriezen, Nathan Ihle, Armin Klein, Fred Jacobson

J Pharm Sci· December 2023

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Streamlined Characterization of an Antibody-Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry.
Alexandre Goyon, Michael Kim, Lu Dai, Christopher Cornell, Fred Jacobson

Anal Chem· December 2019

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Statistical characterization of therapeutic protein modifications.
Tsung-Heng Tsai, Zhiqi Hao, Qiuting Hong, Benjamin Moore, Cinzia Stella, Fred Jacobson

Sci Rep· August 2017

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Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion-reversed phase two dimensional-liquid chromatography.
Yi Li, Cinzia Stella, Laura Zheng, Charity Bechtel, Jason Gruenhagen, Fred Jacobson

J Chromatogr B Analyt Technol Biomed Life Sci· October 2016

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Structural Characterization of Cross-Linked Species in Trastuzumab Emtansine (Kadcyla).
Yan Chen, Michael T Kim, Laura Zheng, Galahad Deperalta, Fred Jacobson

Bioconjug Chem· September 2016

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Statistical modeling of the drug load distribution on trastuzumab emtansine (Kadcyla), a lysine-linked antibody drug conjugate.
Michael T Kim, Yan Chen, Joseph Marhoul, Fred Jacobson

Bioconjug Chem· July 2014

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Charge-based analysis of antibodies with engineered cysteines: from multiple peaks to a single main peak.
Xiaoying Nancy Chen, Mary Nguyen, Fred Jacobson, Jun Ouyang

MAbs· June 2010

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Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer.
Ian E Krop, Muralidhar Beeram, Shanu Modi, Suzanne F Jones, Scott N Holden, Fred Jacobson

J Clin Oncol· June 2010

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Anti-CD22-MCC-DM1 and MC-MMAF conjugates: impact of assay format on pharmacokinetic parameters determination.
Jean-Philippe Stephan, Pamela Chan, Chien Lee, Christopher Nelson, James Michael Elliott, Fred Jacobson

Bioconjug Chem· August 2008

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Protein aggregation and bioprocessing.
Mary E M Cromwell, Eric Hilario, Fred Jacobson

AAPS J· September 2006

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