Publications by authors named "Frederic D Sigoillot"

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Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles.
Jason R Thomas, Claude Shelton, Jason Murphy, Scott Brittain, Mark-Anthony Bray, Frederic D Sigoillot

ACS Chem Biol· April 2024

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DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery.
Jingyao Li, Daniel J Ho, Martin Henault, Chian Yang, Marilisa Neri, Frederic D Sigoillot

ACS Chem Biol· June 2022

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Engineering digitizer circuits for chemical and genetic screens in human cells.
Nicole M Wong, Elizabeth Frias, Frederic D Sigoillot, Justin H Letendre, Marc Hild

Nat Commun· October 2021

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Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma.
Grace P Leung, Tianshu Feng, Frederic D Sigoillot, Felipe C Geyer, Matthew D Shirley

Mol Cancer Res· January 2019

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The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20.
Hui-Jun Lim, Nevena V Dimova, Meng-Kwang Marcus Tan, Frederic D Sigoillot, Randall W King

Mol Cell Biol· November 2013

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A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies.
Frederic D Sigoillot, Jeremy F Huckins, Fuhai Li, Xiaobo Zhou, Stephen T C Wong

PLoS One· February 2012

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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens.
Frederic D Sigoillot, Susan Lyman, Jeremy F Huckins, Britt Adamson, Eunah Chung

Nat Methods· February 2012

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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.
Britt Adamson, Agata Smogorzewska, Frederic D Sigoillot, Randall W King, Stephen J Elledge

Nat Cell Biol· February 2012

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Vigilance and validation: Keys to success in RNAi screening.
Frederic D Sigoillot, Randall W King

ACS Chem Biol· January 2011

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Protein kinase A phosphorylation of the multifunctional protein CAD antagonizes activation by the MAP kinase cascade.
Damian H Kotsis, Elizabeth M Masko, Frederic D Sigoillot, Roberto Di Gregorio, Hedeel I Guy-Evans

Mol Cell Biochem· July 2007

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Protein kinase C modulates the up-regulation of the pyrimidine biosynthetic complex, CAD, by MAP kinase.
Frederic D Sigoillot, Damian H Kotsis, Elizabeth M Masko, Monica Bame, David R Evans

Front Biosci· May 2007

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Nuclear localization and mitogen-activated protein kinase phosphorylation of the multifunctional protein CAD.
Frederic D Sigoillot, Damian H Kotsis, Valerie Serre, Severine M Sigoillot, David R Evans

J Biol Chem· July 2005

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Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells.
Frederic D Sigoillot, Severine M Sigoillot, Hedeel I Guy

Int J Cancer· April 2004

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Cell cycle-dependent regulation of pyrimidine biosynthesis.
Frederic D Sigoillot, J Andrew Berkowski, Severine M Sigoillot, Damian H Kotsis, Hedeel I Guy

J Biol Chem· January 2003

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Autophosphorylation of the mammalian multifunctional protein that initiates de novo pyrimidine biosynthesis.
Frederic D Sigoillot, David R Evans, Hedeel I Guy

J Biol Chem· July 2002

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Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades.
Frederic D Sigoillot, David R Evans, Hedeel I Guy

J Biol Chem· May 2002

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