Publications by authors named "Frederic Triebel"

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Crystal structure of the human LAG-3-HLA-DR1-peptide complex.
Jan Petersen, Carmen Llerena, Bagher Golzarroshan, Camilla Faoro, Frederic Triebel

Sci Immunol· December 2024

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Eftilagimod Alpha (a Soluble LAG-3 Protein) Combined With Pembrolizumab in Second-Line Metastatic NSCLC Refractory to Anti-Programmed Cell Death Protein 1/Programmed Death-Ligand 1-Based Therapy: Final Results from a Phase 2 Study.
Matthew G Krebs, Martin Forster, Margarita Majem, Julio Peguero, Wade Iams, Frédéric Triebel

JTO Clin Res Rep· November 2024

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Eftilagimod Alpha (Soluble LAG3 Protein) Combined with Pembrolizumab as Second-Line Therapy for Patients with Metastatic Head and Neck Squamous Cell Carcinoma.
Martin Forster, Irene Brana, Antonio L Pousa, Bernard Doger, Patricia Roxburgh, Frederic Triebel

Clin Cancer Res· September 2024

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Paclitaxel plus Eftilagimod Alpha, a Soluble LAG-3 Protein, in Metastatic, HR+ Breast Cancer: Results from AIPAC, a Randomized, Placebo Controlled Phase IIb Trial.
Hans Wildiers, Anne Armstrong, Eveline Cuypere, Florence Dalenc, Luc Dirix, Frederic Triebel

Clin Cancer Res· February 2024

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Immunophenotyping of Peripheral Blood Mononuclear Cells in Septic Shock Patients With High-Dimensional Flow Cytometry Analysis Reveals Two Subgroups With Differential Responses to Immunostimulant Drugs.
Ya Wang, Brian Gloss, Benjamin Tang, Suat Dervish, Brigitte Santner-Nanan, Frederic Triebel

Front Immunol· September 2021

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Molecular characterization of HLA class II binding to the LAG-3 T cell co-inhibitory receptor.
Bruce J MacLachlan, Georgina H Mason, Alexander Greenshields-Watson, Frederic Triebel, Awen Gallimore

Eur J Immunol· February 2021

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Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma.
Victoria Atkinson, Adnan Khattak, Andrew Haydon, Melissa Eastgate, Amitesh Roy, Frederic Triebel

J Immunother Cancer· November 2020

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A LAG-3-Specific Agonist Antibody for the Treatment of T Cell-Induced Autoimmune Diseases.
Mathieu Angin, Chrystelle Brignone, Frédéric Triebel

J Immunol· February 2020

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AIPAC: a Phase IIb study of eftilagimod alpha (IMP321 or LAG-3Ig) added to weekly paclitaxel in patients with metastatic breast cancer.
Luc Dirix, Frédéric Triebel

Future Oncol· June 2019

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New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31Annual Meeting of the Society for Immunotherapy of Cancer, 2016.
Prasad S Adusumilli, Edward Cha, Mark Cornfeld, Thomas Davis, Adi Diab, Frederic Triebel

J Immunother Cancer· April 2018

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Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients--Report of a Phase I/IIa Clinical Trial.
Amandine Legat, Hélène Maby-El Hajjami, Petra Baumgaertner, Laurène Cagnon, Samia Abed Maillard, Frédéric Triebel

Clin Cancer Res· March 2016

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Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer.
Nicolas A Giraldo, Etienne Becht, Franck Pagès, Georgios Skliris, Virginie Verkarre, Frederic Triebel

Clin Cancer Res· July 2015

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Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active antitumor immunity.
Chiara Castelli, Frédéric Triebel, Licia Rivoltini, Chiara Camisaschi

Oncoimmunology· November 2014

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Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3.
Chiara Camisaschi, Annamaria De Filippo, Valeria Beretta, Barbara Vergani, Antonello Villa, Frédéric Triebel

J Invest Dermatol· July 2014

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MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial.
Emanuela Romano, Olivier Michielin, Verena Voelter, Julien Laurent, Hélène Bichat, Frédéric Triebel

J Transl Med· April 2014

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MHC class II engagement by its ligand LAG-3 (CD223) contributes to melanoma resistance to apoptosis.
Patrice Hemon, Francette Jean-Louis, Kiran Ramgolam, Chrystelle Brignone, Manuelle Viguier, Frédéric Triebel

J Immunol· May 2011

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First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity.
Chrystelle Brignone, Maya Gutierrez, Fawzia Mefti, Etienne Brain, Rosana Jarcau, Frédéric Triebel

J Transl Med· July 2010

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LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites.
Chiara Camisaschi, Chiara Casati, Francesca Rini, Michela Perego, Annamaria De Filippo, Frédéric Triebel

J Immunol· June 2010

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A phase I pharmacokinetic and biological correlative study of IMP321, a novel MHC class II agonist, in patients with advanced renal cell carcinoma.
Chrystelle Brignone, Bernard Escudier, Caroline Grygar, Manon Marcu, Frédéric Triebel

Clin Cancer Res· October 2009

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CD4+CD25+ regulatory T cells modulate human dendritic cell chemokines via multiple mechanisms: comment on the article by Kolar et al.
Ana-Maria Navarrete, Yann Meslier, Maud Teyssandier, Sébastien André, Sandrine Delignat, Frédéric Triebel

Arthritis Rheum· September 2009

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Lymphocyte activation gene-3 fusion protein increases the potency of a granulocyte macrophage colony-stimulating factor-secreting tumor cell immunotherapy.
Betty Li, Melinda VanRoey, Frederic Triebel, Karin Jooss

Clin Cancer Res· June 2008

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Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation.
Chiara Casati, Chiara Camisaschi, Luisa Novellino, Arabella Mazzocchi, Frédéric Triebel

J Immunol· March 2008

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Depletion of LAG-3 positive cells in cardiac allograft reveals their role in rejection and tolerance.
Thomas Haudebourg, Anne-Sophie Dugast, Flora Coulon, Claire Usal, Frederic Triebel

Transplantation· December 2007

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A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells.
Chrystelle Brignone, Caroline Grygar, Manon Marcu, Knut Schäkel, Frédéric Triebel

J Immunol· September 2007

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Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy.
Jagadeesh Bayry, Sophie Sibéril, Frédéric Triebel, David F Tough, Srini V Kaveri

Drug Discov Today· July 2007

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